(24 nodes) Platelet homeostasis network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0BPI1	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (663 aa)
	A0A4Y0BL20	Phosphodiesterase. (1140 aa)
	A0A4Y0BM02	Phosphodiesterase. (702 aa)
	A0A4Y0BMI3	Nitric oxide synthase; Produces nitric oxide (NO). (1312 aa)
	A0A4Y0BMR8	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (877 aa)
	A0A4Y0BQ33	Phosphodiesterase. (1107 aa)
	A0A4Y0BNU6	Uncharacterized protein. (334 aa)
	A0A182R4T7	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (396 aa)
	A0A182RDQ3	Vitellogenin domain-containing protein. (1462 aa)
	A0A182RID2	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (554 aa)
	A0A182RLY4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1135 aa)
	A0A182RMD0	Phosphodiesterase. (837 aa)
	A0A182RP19	Uncharacterized protein. (3329 aa)
	A0A182RR66	Tyrosine-protein kinase. (537 aa)
	A0A182RZJ3	Uncharacterized protein. (174 aa)
	A0A182RZX1	Uncharacterized protein. (59 aa)
	A0A1Y9HE78	Uncharacterized protein. (1430 aa)
	A0A4Y0AM54	G_PROTEIN_RECEP_F1_2 domain-containing protein. (295 aa)
	A0A4Y0BHV1	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (902 aa)
	A0A4Y0BIF2	Mitogen-activated protein kinase. (358 aa)
	A0A4Y0BIN7	Uncharacterized protein. (353 aa)
	A0A4Y0BJ03	Phosphodiesterase. (1170 aa)
	A0A4Y0BJC2	Uncharacterized protein. (218 aa)
	A0A4Y0BKQ7	Uncharacterized protein. (3102 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182RID2	A0A182RP19	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	Uncharacterized protein.	0.541
A0A182RID2	A0A182RR66	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	Tyrosine-protein kinase.	0.677
A0A182RID2	A0A4Y0BIF2	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	Mitogen-activated protein kinase.	0.665
A0A182RLY4	A0A4Y0BHV1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.451
A0A182RLY4	A0A4Y0BIF2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Mitogen-activated protein kinase.	0.680
A0A182RLY4	A0A4Y0BMI3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Nitric oxide synthase; Produces nitric oxide (NO).	0.882
A0A182RLY4	A0A4Y0BMR8	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.946
A0A182RMD0	A0A4Y0BM02	Phosphodiesterase.	Phosphodiesterase.	0.933
A0A182RP19	A0A182RID2	Uncharacterized protein.	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.541
A0A182RP19	A0A182RR66	Uncharacterized protein.	Tyrosine-protein kinase.	0.569
A0A182RP19	A0A1Y9HE78	Uncharacterized protein.	Uncharacterized protein.	0.433
A0A182RP19	A0A4Y0BIF2	Uncharacterized protein.	Mitogen-activated protein kinase.	0.583
A0A182RP19	A0A4Y0BPI1	Uncharacterized protein.	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.541
A0A182RR66	A0A182RID2	Tyrosine-protein kinase.	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.677
A0A182RR66	A0A182RP19	Tyrosine-protein kinase.	Uncharacterized protein.	0.569
A0A182RR66	A0A4Y0BIF2	Tyrosine-protein kinase.	Mitogen-activated protein kinase.	0.797
A0A182RR66	A0A4Y0BPI1	Tyrosine-protein kinase.	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.677
A0A1Y9HE78	A0A182RP19	Uncharacterized protein.	Uncharacterized protein.	0.433
A0A4Y0BHV1	A0A182RLY4	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.451
A0A4Y0BHV1	A0A4Y0BKQ7	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Uncharacterized protein.	0.470