17 items (Anopheles funestus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R4Q0	Uncharacterized protein. (1227 aa)
	A0A182R4B0	ERCC4 domain-containing protein. (480 aa)
	A0A4Y0BQD3	Uncharacterized protein. (1159 aa)
	A0A4Y0BNI3	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa)
	A0A4Y0BL97	ANK_REP_REGION domain-containing protein. (1313 aa)
	A0A4Y0BFV6	GIY-YIG domain-containing protein. (184 aa)
	A0A4Y0BEI8	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (680 aa)
	A0A1Y9HDX7	Asparaginyl-tRNA synthetase. (553 aa)
	A0A182S019	Rad51 domain-containing protein. (310 aa)
	A0A182RH57	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (356 aa)
	A0A182RF05	Uncharacterized protein. (1628 aa)
	A0A182RDL1	RECA_2 domain-containing protein. (329 aa)
	A0A182RCK2	Uncharacterized protein. (2053 aa)
	A0A182R8E4	RECA_2 domain-containing protein. (262 aa)
	A0A182R757	ERCC4 domain-containing protein. (311 aa)
	A0A182R703	DUF1767 domain-containing protein. (642 aa)
	A0A182R5W4	RECA_2 domain-containing protein. (140 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R4B0	A0A182R4Q0	ERCC4 domain-containing protein.	Uncharacterized protein.	0.963
A0A182R4B0	A0A182R5W4	ERCC4 domain-containing protein.	RECA_2 domain-containing protein.	0.894
A0A182R4B0	A0A182R703	ERCC4 domain-containing protein.	DUF1767 domain-containing protein.	0.961
A0A182R4B0	A0A182R757	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.996
A0A182R4B0	A0A182R8E4	ERCC4 domain-containing protein.	RECA_2 domain-containing protein.	0.903
A0A182R4B0	A0A182RCK2	ERCC4 domain-containing protein.	Uncharacterized protein.	0.780
A0A182R4B0	A0A182RDL1	ERCC4 domain-containing protein.	RECA_2 domain-containing protein.	0.959
A0A182R4B0	A0A182RF05	ERCC4 domain-containing protein.	Uncharacterized protein.	0.965
A0A182R4B0	A0A182RH57	ERCC4 domain-containing protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.857
A0A182R4B0	A0A182S019	ERCC4 domain-containing protein.	Rad51 domain-containing protein.	0.749
A0A182R4B0	A0A1Y9HDX7	ERCC4 domain-containing protein.	Asparaginyl-tRNA synthetase.	0.957
A0A182R4B0	A0A4Y0BEI8	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.942
A0A182R4B0	A0A4Y0BFV6	ERCC4 domain-containing protein.	GIY-YIG domain-containing protein.	0.857
A0A182R4B0	A0A4Y0BL97	ERCC4 domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.578
A0A182R4B0	A0A4Y0BNI3	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.942
A0A182R4B0	A0A4Y0BQD3	ERCC4 domain-containing protein.	Uncharacterized protein.	0.578
A0A182R4Q0	A0A182R4B0	Uncharacterized protein.	ERCC4 domain-containing protein.	0.963
A0A182R4Q0	A0A182R5W4	Uncharacterized protein.	RECA_2 domain-containing protein.	0.681
A0A182R4Q0	A0A182R703	Uncharacterized protein.	DUF1767 domain-containing protein.	0.628
A0A182R4Q0	A0A182R757	Uncharacterized protein.	ERCC4 domain-containing protein.	0.913