STRINGSTRING
A0A4Y0BUJ9 A0A4Y0BUJ9 A0A182R1W2 A0A182R1W2 A0A182R4B0 A0A182R4B0 A0A182R4Q0 A0A182R4Q0 A0A182R4V5 A0A182R4V5 A0A182R4W4 A0A182R4W4 A0A182R5W4 A0A182R5W4 A0A182R6N9 A0A182R6N9 A0A182R703 A0A182R703 A0A182R757 A0A182R757 A0A182R8E4 A0A182R8E4 A0A182R9J3 A0A182R9J3 A0A182RCK2 A0A182RCK2 A0A182RD17 A0A182RD17 A0A182RDL1 A0A182RDL1 A0A182RDN7 A0A182RDN7 A0A182RDX0 A0A182RDX0 A0A182REJ3 A0A182REJ3 A0A182RF05 A0A182RF05 A0A182RF37 A0A182RF37 Fen1 Fen1 A0A182RGW9 A0A182RGW9 A0A182RH57 A0A182RH57 A0A182RHY8 A0A182RHY8 A0A182RIW4 A0A182RIW4 A0A182RIX6 A0A182RIX6 A0A182RJQ0 A0A182RJQ0 A0A182RJY6 A0A182RJY6 A0A182RL37 A0A182RL37 A0A182RLK2 A0A182RLK2 A0A182RME0 A0A182RME0 A0A182RND2 A0A182RND2 A0A182RNF2 A0A182RNF2 A0A182RPL3 A0A182RPL3 A0A182RQM2 A0A182RQM2 A0A182RRS7 A0A182RRS7 A0A182RSD6 A0A182RSD6 A0A182RSY5 A0A182RSY5 A0A182RUI3 A0A182RUI3 A0A182RV72 A0A182RV72 A0A182RVJ2 A0A182RVJ2 A0A182RXT0 A0A182RXT0 A0A182S015 A0A182S015 A0A182S019 A0A182S019 A0A1D6TC74 A0A1D6TC74 A0A1Y9HDX7 A0A1Y9HDX7 A0A1Y9HEZ3 A0A1Y9HEZ3 A0A4Y0AV06 A0A4Y0AV06 A0A4Y0BDM2 A0A4Y0BDM2 A0A4Y0BEB8 A0A4Y0BEB8 A0A4Y0BEI8 A0A4Y0BEI8 A0A4Y0BF84 A0A4Y0BF84 A0A4Y0BF97 A0A4Y0BF97 A0A4Y0BFV6 A0A4Y0BFV6 A0A4Y0BGE7 A0A4Y0BGE7 A0A4Y0BGH3 A0A4Y0BGH3 A0A4Y0BGR5 A0A4Y0BGR5 A0A4Y0BGS0 A0A4Y0BGS0 A0A4Y0BI68 A0A4Y0BI68 A0A4Y0BI70 A0A4Y0BI70 A0A4Y0BJE3 A0A4Y0BJE3 A0A4Y0BJZ8 A0A4Y0BJZ8 A0A4Y0BKQ4 A0A4Y0BKQ4 A0A4Y0BKT2 A0A4Y0BKT2 A0A4Y0BL97 A0A4Y0BL97 A0A4Y0BNI3 A0A4Y0BNI3 A0A4Y0BP53 A0A4Y0BP53 A0A4Y0BQD3 A0A4Y0BQD3 A0A4Y0BQP5 A0A4Y0BQP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4Y0BUJ9Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2289 aa)
A0A182R1W2Uncharacterized protein. (1239 aa)
A0A182R4B0ERCC4 domain-containing protein. (480 aa)
A0A182R4Q0Uncharacterized protein. (1227 aa)
A0A182R4V53'-5' exonuclease domain-containing protein. (810 aa)
A0A182R4W4Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (457 aa)
A0A182R5W4RECA_2 domain-containing protein. (140 aa)
A0A182R6N9Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (649 aa)
A0A182R703DUF1767 domain-containing protein. (642 aa)
A0A182R757ERCC4 domain-containing protein. (311 aa)
A0A182R8E4RECA_2 domain-containing protein. (262 aa)
A0A182R9J33'-5' exonuclease domain-containing protein. (313 aa)
A0A182RCK2Uncharacterized protein. (2053 aa)
A0A182RD17Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (509 aa)
A0A182RDL1RECA_2 domain-containing protein. (329 aa)
A0A182RDN7Uncharacterized protein. (465 aa)
A0A182RDX0Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (309 aa)
A0A182REJ3Uncharacterized protein. (1323 aa)
A0A182RF05Uncharacterized protein. (1628 aa)
A0A182RF37RING-type domain-containing protein. (712 aa)
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
A0A182RGW9Uncharacterized protein. (620 aa)
A0A182RH57Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (356 aa)
A0A182RHY8ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (976 aa)
A0A182RIW4FHA domain-containing protein. (772 aa)
A0A182RIX6Poly [ADP-ribose] polymerase. (1001 aa)
A0A182RJQ0Uncharacterized protein. (206 aa)
A0A182RJY6TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (287 aa)
A0A182RL37Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A182RLK2Uncharacterized protein. (358 aa)
A0A182RME0TIMELESS domain-containing protein. (1296 aa)
A0A182RND2DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (339 aa)
A0A182RNF2Uncharacterized protein. (1979 aa)
A0A182RPL3Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
A0A182RQM2Uncharacterized protein. (735 aa)
A0A182RRS7Zinc-hook domain-containing protein. (1308 aa)
A0A182RSD6Deacetylase sirtuin-type domain-containing protein. (2085 aa)
A0A182RSY5Uncharacterized protein. (1571 aa)
A0A182RUI3Uncharacterized protein. (867 aa)
A0A182RV72Uncharacterized protein. (2087 aa)
A0A182RVJ2Protein kinase domain-containing protein. (393 aa)
A0A182RXT0FHA domain-containing protein. (271 aa)
A0A182S015Reverse transcriptase domain-containing protein. (340 aa)
A0A182S019Rad51 domain-containing protein. (310 aa)
A0A1D6TC74Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A1Y9HDX7Asparaginyl-tRNA synthetase. (553 aa)
A0A1Y9HEZ3Mono-ADP-ribosyltransferase sirtuin. (359 aa)
A0A4Y0AV06BRCT domain-containing protein. (1575 aa)
A0A4Y0BDM2Deacetylase sirtuin-type domain-containing protein. (2084 aa)
A0A4Y0BEB8Uncharacterized protein. (1571 aa)
A0A4Y0BEI8DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (680 aa)
A0A4Y0BF84Uncharacterized protein. (609 aa)
A0A4Y0BF97Uncharacterized protein. (366 aa)
A0A4Y0BFV6GIY-YIG domain-containing protein. (184 aa)
A0A4Y0BGE7Uncharacterized protein. (460 aa)
A0A4Y0BGH3Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (191 aa)
A0A4Y0BGR5Uncharacterized protein. (913 aa)
A0A4Y0BGS0Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (428 aa)
A0A4Y0BI68Uncharacterized protein. (96 aa)
A0A4Y0BI70KxDL domain-containing protein. (254 aa)
A0A4Y0BJE3Uncharacterized protein. (528 aa)
A0A4Y0BJZ8FAT domain-containing protein. (530 aa)
A0A4Y0BKQ4KxDL domain-containing protein. (254 aa)
A0A4Y0BKT2EGF-like domain-containing protein. (248 aa)
A0A4Y0BL97ANK_REP_REGION domain-containing protein. (1313 aa)
A0A4Y0BNI3DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa)
A0A4Y0BP53Uncharacterized protein. (478 aa)
A0A4Y0BQD3Uncharacterized protein. (1159 aa)
A0A4Y0BQP5Uncharacterized protein. (707 aa)
Your Current Organism:
Anopheles funestus
NCBI taxonomy Id: 62324
Other names: A. funestus
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