STRINGSTRING
A0A4Y0BRP8 A0A4Y0BRP8 A0A4Y0BTX5 A0A4Y0BTX5 W6FTC9_ANOFN W6FTC9_ANOFN A0A182RX78 A0A182RX78 A0A182RMA2 A0A182RMA2 A0A182RMZ4 A0A182RMZ4 A0A182RPL3 A0A182RPL3 A0A182RRD7 A0A182RRD7 A0A182RSA0 A0A182RSA0 A0A182RSN2 A0A182RSN2 A0A182RXB5 A0A182RXB5 A0A182RSY5 A0A182RSY5 A0A182RT78 A0A182RT78 A0A182RTR4 A0A182RTR4 A0A182RLK2 A0A182RLK2 A0A182RLE9 A0A182RLE9 A0A182RL37 A0A182RL37 A0A182RI25 A0A182RI25 A0A182RHY8 A0A182RHY8 A0A182RHY4 A0A182RHY4 A0A182RHU0 A0A182RHU0 A0A182RH52 A0A182RH52 A0A182RGB2 A0A182RGB2 A0A182RG11 A0A182RG11 A0A182RFZ4 A0A182RFZ4 A0A182RFP9 A0A182RFP9 A0A182RF37 A0A182RF37 A0A182RF05 A0A182RF05 A0A182REX6 A0A182REX6 A0A182RU99 A0A182RU99 A0A182RUI3 A0A182RUI3 A0A182RV72 A0A182RV72 A0A182RVF7 A0A182RVF7 A0A182RVJ2 A0A182RVJ2 A0A182RWG0 A0A182RWG0 A0A182RE54 A0A182RE54 A0A182RE53 A0A182RE53 A0A182RXK1 A0A182RXK1 A0A182RXT0 A0A182RXT0 A0A182RDX0 A0A182RDX0 A0A182RXT7 A0A182RXT7 A0A182RY47 A0A182RY47 A0A182S015 A0A182S015 A0A1D6TC74 A0A1D6TC74 A0A4Y0AV06 A0A4Y0AV06 A0A4Y0BCX6 A0A4Y0BCX6 A0A4Y0BDQ7 A0A4Y0BDQ7 A0A4Y0BEB8 A0A4Y0BEB8 A0A4Y0BEE5 A0A4Y0BEE5 A0A4Y0BEI8 A0A4Y0BEI8 A0A4Y0BF84 A0A4Y0BF84 A0A4Y0BF97 A0A4Y0BF97 A0A4Y0BGE7 A0A4Y0BGE7 A0A4Y0BGR5 A0A4Y0BGR5 A0A4Y0BH52 A0A4Y0BH52 A0A4Y0BHD8 A0A4Y0BHD8 A0A4Y0BHX0 A0A4Y0BHX0 A0A4Y0BHZ6 A0A4Y0BHZ6 A0A4Y0BI68 A0A4Y0BI68 A0A182RCW2 A0A182RCW2 A0A182RCN4 A0A182RCN4 A0A182RCF7 A0A182RCF7 A0A182R9J3 A0A182R9J3 A0A182R7S6 A0A182R7S6 A0A182R703 A0A182R703 A0A182R6W1 A0A182R6W1 A0A182R5P0 A0A182R5P0 A0A182R4V5 A0A182R4V5 A0A182R410 A0A182R410 A0A182R371 A0A182R371 MCM7 MCM7 A0A182R1W2 A0A182R1W2 A0A182R1J3 A0A182R1J3 A0A4Y0BI70 A0A4Y0BI70 A0A4Y0BJE3 A0A4Y0BJE3 A0A4Y0BKQ4 A0A4Y0BKQ4 A0A4Y0BL97 A0A4Y0BL97 A0A4Y0BLD9 A0A4Y0BLD9 A0A4Y0BM56 A0A4Y0BM56 A0A4Y0BNI3 A0A4Y0BNI3 A0A4Y0BNN3 A0A4Y0BNN3 A0A4Y0BP53 A0A4Y0BP53 A0A4Y0BPQ4 A0A4Y0BPQ4 A0A4Y0BQD3 A0A4Y0BQD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4Y0BRP8Uncharacterized protein. (254 aa)
A0A4Y0BTX5MCM domain-containing protein; Belongs to the MCM family. (832 aa)
W6FTC9_ANOFN14-3-3 zeta; Belongs to the 14-3-3 family. (248 aa)
A0A182RX78DNA helicase; Belongs to the MCM family. (899 aa)
A0A182RMA2RPA_C domain-containing protein. (246 aa)
A0A182RMZ4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (459 aa)
A0A182RPL3Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
A0A182RRD7ORC_WH_C domain-containing protein. (699 aa)
A0A182RSA0Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2649 aa)
A0A182RSN2Protein kinase domain-containing protein. (582 aa)
A0A182RXB5AAA domain-containing protein. (360 aa)
A0A182RSY5Uncharacterized protein. (1571 aa)
A0A182RT78Protein kinase domain-containing protein. (569 aa)
A0A182RTR4AAA domain-containing protein. (327 aa)
A0A182RLK2Uncharacterized protein. (358 aa)
A0A182RLE9Uncharacterized protein. (1921 aa)
A0A182RL37Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A182RI25DNA helicase; Belongs to the MCM family. (733 aa)
A0A182RHY8ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (976 aa)
A0A182RHY4Rhodanese domain-containing protein. (649 aa)
A0A182RHU0Uncharacterized protein. (718 aa)
A0A182RH52Uncharacterized protein. (310 aa)
A0A182RGB2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
A0A182RG11DNA helicase; Belongs to the MCM family. (822 aa)
A0A182RFZ414_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)
A0A182RFP914-3-3 zeta; Belongs to the 14-3-3 family. (248 aa)
A0A182RF37RING-type domain-containing protein. (712 aa)
A0A182RF05Uncharacterized protein. (1628 aa)
A0A182REX6Uncharacterized protein. (477 aa)
A0A182RU99Wee1-like protein kinase. (645 aa)
A0A182RUI3Uncharacterized protein. (867 aa)
A0A182RV72Uncharacterized protein. (2087 aa)
A0A182RVF7Checkpoint protein; Belongs to the HUS1 family. (293 aa)
A0A182RVJ2Protein kinase domain-containing protein. (393 aa)
A0A182RWG0Rep_fac_C domain-containing protein. (358 aa)
A0A182RE54Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (880 aa)
A0A182RE53DNA helicase; Belongs to the MCM family. (876 aa)
A0A182RXK1Protein kinase domain-containing protein. (667 aa)
A0A182RXT0FHA domain-containing protein. (271 aa)
A0A182RDX0Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (309 aa)
A0A182RXT7Uncharacterized protein. (569 aa)
A0A182RY47DBF4-type domain-containing protein. (3248 aa)
A0A182S015Reverse transcriptase domain-containing protein. (340 aa)
A0A1D6TC74Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A4Y0AV06BRCT domain-containing protein. (1575 aa)
A0A4Y0BCX6Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (482 aa)
A0A4Y0BDQ7Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2661 aa)
A0A4Y0BEB8Uncharacterized protein. (1571 aa)
A0A4Y0BEE5AAA domain-containing protein. (348 aa)
A0A4Y0BEI8DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (680 aa)
A0A4Y0BF84Uncharacterized protein. (609 aa)
A0A4Y0BF97Uncharacterized protein. (366 aa)
A0A4Y0BGE7Uncharacterized protein. (460 aa)
A0A4Y0BGR5Uncharacterized protein. (913 aa)
A0A4Y0BH52Uncharacterized protein. (718 aa)
A0A4Y0BHD8Uncharacterized protein. (191 aa)
A0A4Y0BHX0Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (482 aa)
A0A4Y0BHZ6Piezo-type mechanosensitive ion channel component. (2989 aa)
A0A4Y0BI68Uncharacterized protein. (96 aa)
A0A182RCW2P53 domain-containing protein. (440 aa)
A0A182RCN4Uncharacterized protein. (929 aa)
A0A182RCF7AAA_16 domain-containing protein. (464 aa)
A0A182R9J33'-5' exonuclease domain-containing protein. (313 aa)
A0A182R7S6Uncharacterized protein. (120 aa)
A0A182R703DUF1767 domain-containing protein. (642 aa)
A0A182R6W1DNA helicase; Belongs to the MCM family. (812 aa)
A0A182R5P0P53 domain-containing protein. (399 aa)
A0A182R4V53'-5' exonuclease domain-containing protein. (810 aa)
A0A182R410Mcm10 domain-containing protein. (794 aa)
A0A182R371Uncharacterized protein; Belongs to the cyclin family. (744 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (717 aa)
A0A182R1W2Uncharacterized protein. (1239 aa)
A0A182R1J3MCM domain-containing protein; Belongs to the MCM family. (1095 aa)
A0A4Y0BI70KxDL domain-containing protein. (254 aa)
A0A4Y0BJE3Uncharacterized protein. (528 aa)
A0A4Y0BKQ4KxDL domain-containing protein. (254 aa)
A0A4Y0BL97ANK_REP_REGION domain-containing protein. (1313 aa)
A0A4Y0BLD9Uncharacterized protein. (264 aa)
A0A4Y0BM56Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (462 aa)
A0A4Y0BNI3DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa)
A0A4Y0BNN3Uncharacterized protein. (1215 aa)
A0A4Y0BP53Uncharacterized protein. (478 aa)
A0A4Y0BPQ4MCM_lid domain-containing protein. (251 aa)
A0A4Y0BQD3Uncharacterized protein. (1159 aa)
Your Current Organism:
Anopheles funestus
NCBI taxonomy Id: 62324
Other names: A. funestus
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