(94 nodes) CDC42 GTPase cycle network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4Y0B257	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (213 aa)
	A0A4Y0BRZ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1846 aa)
	A0A4Y0BWD5	Uncharacterized protein. (1095 aa)
	A0A4Y0BHF6	Uncharacterized protein. (1494 aa)
	A0A4Y0BFY0	Uncharacterized protein. (1279 aa)
	A0A4Y0BH21	Uncharacterized protein. (4052 aa)
	A0A4Y0BG28	Uncharacterized protein. (2335 aa)
	A0A4Y0BG13	Protein kinase domain-containing protein. (194 aa)
	A0A2Y9D1P9	Uncharacterized protein. (1287 aa)
	A0A2Y9D1W5	Uncharacterized protein. (2547 aa)
	A0A4Y0ALV6	Uncharacterized protein. (1238 aa)
	A0A4Y0ASC9	Uncharacterized protein. (1636 aa)
	A0A4Y0AUQ3	Uncharacterized protein. (1351 aa)
	A0A4Y0AWS6	Uncharacterized protein. (852 aa)
	A0A4Y0AZS8	Phospholipase. (1268 aa)
	A0A4Y0B0Y4	Phospholipase. (1280 aa)
	A0A4Y0B101	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (213 aa)
	A0A4Y0BKM4	Uncharacterized protein. (2291 aa)
	A0A4Y0BKN2	Rho-GAP domain-containing protein. (484 aa)
	A0A4Y0BLA2	Uncharacterized protein. (1313 aa)
	A0A4Y0BLJ0	Uncharacterized protein. (1978 aa)
	A0A4Y0BLV6	Uncharacterized protein. (387 aa)
	A0A4Y0BMR3	Uncharacterized protein. (1690 aa)
	A0A4Y0BNK3	Uncharacterized protein. (1545 aa)
	A0A4Y0BNL3	Uncharacterized protein; Belongs to the DOCK family. (2033 aa)
	A0A4Y0BPE8	Uncharacterized protein. (673 aa)
	A0A4Y0BPJ8	Uncharacterized protein. (1143 aa)
	A0A4Y0BPV3	Uncharacterized protein. (469 aa)
	A0A4Y0BQQ2	Uncharacterized protein. (1921 aa)
	A0A4Y0BQQ8	Uncharacterized protein. (1735 aa)
	A0A4Y0BRR5	Uncharacterized protein. (1789 aa)
	A0A4Y0BK94	Uncharacterized protein. (1446 aa)
	A0A4Y0BK22	Uncharacterized protein. (2820 aa)
	A0A4Y0BJV6	Uncharacterized protein. (1892 aa)
	A0A4Y0BJL5	Uncharacterized protein. (2330 aa)
	A0A4Y0BKH0	Uncharacterized protein. (779 aa)
	A0A182RB32	Uncharacterized protein. (1676 aa)
	A0A182RB09	V-SNARE coiled-coil homology domain-containing protein. (112 aa)
	A0A182RAI9	Uncharacterized protein. (200 aa)
	A0A182R8E7	Uncharacterized protein. (154 aa)
	A0A4Y0BEL1	WASH_WAHD domain-containing protein. (471 aa)
	A0A4Y0BCY3	Uncharacterized protein. (515 aa)
	A0A4Y0B7J2	Uncharacterized protein. (1411 aa)
	A0A4Y0B6A1	Uncharacterized protein. (1142 aa)
	A0A4Y0B3R4	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (213 aa)
	A0A182R7T1	FH2 domain-containing protein. (1626 aa)
	A0A182R6T0	Uncharacterized protein; Belongs to the DOCK family. (2078 aa)
	A0A182R623	Uncharacterized protein. (207 aa)
	A0A182R5E5	Vang-like protein. (589 aa)
	A0A182R4B1	Rho-GAP domain-containing protein. (690 aa)
	A0A182R465	Uncharacterized protein. (1015 aa)
	A0A182R316	Uncharacterized protein. (129 aa)
	A0A182R287	Uncharacterized protein. (1380 aa)
	A0A182R1L7	Rho-GAP domain-containing protein. (1057 aa)
	A0A4Y0BHJ1	Uncharacterized protein. (1161 aa)
	A0A4Y0BI89	Uncharacterized protein. (1194 aa)
	A0A4Y0BIB4	Uncharacterized protein. (1176 aa)
	A0A4Y0BIG7	Uncharacterized protein; Belongs to the DOCK family. (2233 aa)
	A0A4Y0BIK4	Uncharacterized protein. (631 aa)
	A0A4Y0BIK6	Uncharacterized protein. (1547 aa)
	A0A4Y0BIU0	Uncharacterized protein. (1321 aa)
	A0A4Y0BJ69	Uncharacterized protein; Belongs to the DOCK family. (2214 aa)
	A0A4Y0BJ95	Uncharacterized protein. (1209 aa)
	A0A4Y0BJH2	Uncharacterized protein. (1188 aa)
	A0A182RE16	Uncharacterized protein. (1465 aa)
	A0A182REG2	Uncharacterized protein. (615 aa)
	A0A182REK6	Uncharacterized protein. (2338 aa)
	A0A182REL4	WASH_WAHD domain-containing protein. (471 aa)
	A0A182RGP4	Uncharacterized protein. (1121 aa)
	A0A182RHI9	Uncharacterized protein. (748 aa)
	A0A182RIU8	Uncharacterized protein. (314 aa)
	A0A182RJ84	Uncharacterized protein. (950 aa)
	A0A182RJC2	Uncharacterized protein. (2151 aa)
	A0A182RJF3	Uncharacterized protein. (700 aa)
	A0A182RJR3	Uncharacterized protein. (178 aa)
	A0A182RLU9	Phospholipase. (1257 aa)
	A0A182RNH4	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (213 aa)
	A0A182RPH1	DH domain-containing protein. (968 aa)
	A0A182RQC1	Uncharacterized protein. (690 aa)
	A0A182RRW3	Arf-GAP domain-containing protein. (595 aa)
	A0A182RSK0	Uncharacterized protein. (642 aa)
	A0A182RTZ5	Uncharacterized protein. (497 aa)
	A0A182RUM2	Protein kinase domain-containing protein. (532 aa)
	A0A182RVR0	FERM domain-containing protein. (4687 aa)
	A0A4Y0BJI1	Uncharacterized protein. (1258 aa)
	A0A182RVU4	Uncharacterized protein. (1719 aa)
	A0A182RWF0	Uncharacterized protein. (1166 aa)
	A0A182RWS3	Anopheline antiplatelet protein. (257 aa)
	A0A182RXF5	Uncharacterized protein. (1417 aa)
	A0A182RYE9	BTB domain-containing protein. (842 aa)
	A0A182RYW6	Non-specific serine/threonine protein kinase. (869 aa)
	A0A1I8JUX7	RalA-binding protein. (413 aa)
	A0A1Y9HDZ3	Uncharacterized protein. (150 aa)
	A0A2C9GWT0	CRIB domain-containing protein. (85 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R1L7	A0A182R4B1	Rho-GAP domain-containing protein.	Rho-GAP domain-containing protein.	0.518
A0A182R1L7	A0A182REG2	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.529
A0A182R1L7	A0A182RJ84	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.467
A0A182R1L7	A0A182RSK0	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.574
A0A182R1L7	A0A182RTZ5	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.665
A0A182R1L7	A0A182RVU4	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.454
A0A182R1L7	A0A4Y0BG28	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.481
A0A182R1L7	A0A4Y0BKN2	Rho-GAP domain-containing protein.	Rho-GAP domain-containing protein.	0.740
A0A182R1L7	A0A4Y0BPV3	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.516
A0A182R1L7	A0A4Y0BQQ8	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.498
A0A182R287	A0A182RB32	Uncharacterized protein.	Uncharacterized protein.	0.593
A0A182R287	A0A182REK6	Uncharacterized protein.	Uncharacterized protein.	0.624
A0A182R287	A0A182RGP4	Uncharacterized protein.	Uncharacterized protein.	0.761
A0A182R287	A0A182RIU8	Uncharacterized protein.	Uncharacterized protein.	0.545
A0A182R287	A0A182RSK0	Uncharacterized protein.	Uncharacterized protein.	0.984
A0A182R287	A0A2Y9D1P9	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A182R287	A0A2Y9D1W5	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A182R287	A0A4Y0ASC9	Uncharacterized protein.	Uncharacterized protein.	0.593
A0A182R287	A0A4Y0AUQ3	Uncharacterized protein.	Uncharacterized protein.	0.624
A0A182R287	A0A4Y0BH21	Uncharacterized protein.	Uncharacterized protein.	0.506