(18 nodes) Actin network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182RLW6	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (564 aa)
	A0A182RM36	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (395 aa)
	A0A182RNV8	Uncharacterized protein; Belongs to the actin family. (376 aa)
	A0A182RTL3	Uncharacterized protein. (376 aa)
	A0A182RTN0	Uncharacterized protein; Belongs to the actin family. (418 aa)
	A0A182S4J5	Uncharacterized protein. (376 aa)
	A0A182S528	Uncharacterized protein. (376 aa)
	A0A182S529	Uncharacterized protein. (376 aa)
	A0A4Y0BDD0	Uncharacterized protein; Belongs to the actin family. (404 aa)
	A0A4Y0BR39	Uncharacterized protein; Belongs to the actin family. (655 aa)
	A0A4Y0BRC5	Uncharacterized protein; Belongs to the actin family. (383 aa)
	A0A182R4I2	Uncharacterized protein; Belongs to the actin family. (404 aa)
	A0A182R8J6	Uncharacterized protein. (376 aa)
	A0A182R8J7	Uncharacterized protein. (376 aa)
	A0A182R8J8	Uncharacterized protein. (376 aa)
	A0A182RK07	Uncharacterized protein; Belongs to the actin family. (422 aa)
	A0A182RKH8	Uncharacterized protein; Belongs to the actin family. (229 aa)
	A0A182RKQ1	Uncharacterized protein. (376 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R4I2	A0A182R8J6	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182R8J7	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182R8J8	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182RK07	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.448
A0A182R4I2	A0A182RKH8	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.401
A0A182R4I2	A0A182RKQ1	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182RLW6	Uncharacterized protein; Belongs to the actin family.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.469
A0A182R4I2	A0A182RM36	Uncharacterized protein; Belongs to the actin family.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.546
A0A182R4I2	A0A182RNV8	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.422
A0A182R4I2	A0A182RTL3	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182RTN0	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.581
A0A182R4I2	A0A182S4J5	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182S528	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R4I2	A0A182S529	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.401
A0A182R8J6	A0A182R4I2	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.401
A0A182R8J6	A0A182RK07	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.892
A0A182R8J6	A0A182RLW6	Uncharacterized protein.	Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.	0.878
A0A182R8J6	A0A182RM36	Uncharacterized protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.882
A0A182R8J6	A0A182RNV8	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.728
A0A182R8J6	A0A182RTN0	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.883