(61 nodes) Metabolism of xenobiotics by cytochrome P450 network (Anopheles funestus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R7A9	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (516 aa)
	GSTe2	Glutathione S-transferase epsilon 2; Belongs to the GST superfamily. (221 aa)
	G0XSZ5_ANOFN	Glutathione s-transferase E7. (223 aa)
	A0A4Y0BLK9	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (524 aa)
	A0A4Y0BIS4	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	A0A4Y0BFN0	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa)
	A0A4Y0BFD5	Uncharacterized protein. (65 aa)
	A0A4Y0B3A3	Glutathione S-transferase; Belongs to the GST superfamily. (259 aa)
	A0A2Y9D1U5	PKS_ER domain-containing protein. (437 aa)
	A0A1Y9HDJ0	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (522 aa)
	A0A1I8JUN8	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa)
	A0A1I8JUM7	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (537 aa)
	A0A1I8JU37	Glutathione transferase microsomal. (152 aa)
	A0A182S5E4	Glutathione S-transferase; Belongs to the GST superfamily. (209 aa)
	A0A182S5E3	Glutathione S-transferase. (207 aa)
	A0A182S5E2	Glutathione S-transferase; Belongs to the GST superfamily. (215 aa)
	A0A182S5E1	Glutathione S-transferase; Belongs to the GST superfamily. (219 aa)
	A0A182S5D9	Glutathione S-transferase; Belongs to the GST superfamily. (222 aa)
	A0A182S4X2	Glutathione S-transferase; Belongs to the GST superfamily. (210 aa)
	A0A182S4X1	Glutathione S-transferase; Belongs to the GST superfamily. (216 aa)
	A0A182S4W9	Glutathione S-transferase. (210 aa)
	A0A182S4U0	Glutathione S-transferase. (224 aa)
	A0A182S4T9	Glutathione S-transferase. (224 aa)
	A0A182S4T7	Glutathione S-transferase; Belongs to the GST superfamily. (223 aa)
	A0A182S4T6	Glutathione S-transferase. (223 aa)
	A0A182S4P7	Glutathione S-transferase; Belongs to the GST superfamily. (214 aa)
	A0A182S4P6	Glutathione S-transferase. (214 aa)
	A0A182S4P5	Glutathione S-transferase. (290 aa)
	A0A182S4J1	Glutathione S-transferase; Belongs to the GST superfamily. (222 aa)
	A0A182RZ27	Uncharacterized protein. (486 aa)
	A0A182RYP2	Glutathione S-transferase. (215 aa)
	A0A182RYN4	Glutathione S-transferase; Belongs to the GST superfamily. (218 aa)
	A0A182RY93	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (517 aa)
	A0A182RY16	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (517 aa)
	A0A182RSI4	Glutathione S-transferase; Belongs to the GST superfamily. (233 aa)
	A0A182RS16	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (521 aa)
	A0A182RRD5	Glutathione S-transferase. (58 aa)
	A0A182RRD4	Glutathione S-transferase; Belongs to the GST superfamily. (203 aa)
	A0A182RRC4	Glutathione transferase microsomal. (147 aa)
	A0A182RRC3	GFO_IDH_MocA domain-containing protein. (339 aa)
	A0A182RQS5	Uncharacterized protein. (279 aa)
	A0A182RQ85	Glutathione S-transferase. (222 aa)
	A0A182RPC3	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)
	A0A182RM19	Glutathione S-transferase; Belongs to the GST superfamily. (234 aa)
	A0A182RJJ6	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
	A0A182RIU5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (377 aa)
	A0A182RHS4	Uncharacterized protein. (514 aa)
	A0A182RH80	Glutathione S-transferase; Belongs to the GST superfamily. (229 aa)
	A0A182RGY9	Uncharacterized protein. (536 aa)
	A0A182RG55	PKS_ER domain-containing protein. (408 aa)
	A0A182RG54	GFO_IDH_MocA domain-containing protein. (337 aa)
	A0A182RFJ4	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (521 aa)
	A0A182RDT2	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
	A0A182RBM8	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (517 aa)
	A0A182RBM5	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (537 aa)
	A0A182RAT9	Glutathione S-transferase. (218 aa)
	A0A182R9K6	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (537 aa)
	A0A182R932	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (537 aa)
	A0A182R7K7	Glutathione transferase microsomal. (152 aa)
	A0A182R7K5	Glutathione transferase microsomal. (151 aa)
	A0A182R3D8	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (550 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182R3D8	A0A182R9K6	A0A182R3D8	A0A182R9K6	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.	0.462
A0A182R3D8	A0A182RIU5	A0A182R3D8	A0A182RIU5	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.728
A0A182R3D8	A0A182RJJ6	A0A182R3D8	A0A182RJJ6	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.748
A0A182R3D8	A0A182RPC3	A0A182R3D8	A0A182RPC3	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.609
A0A182R7A9	A0A182R9K6	A0A182R7A9	A0A182R9K6	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family.	0.435
A0A182R7A9	A0A182RIU5	A0A182R7A9	A0A182RIU5	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.909
A0A182R7A9	A0A182RJJ6	A0A182R7A9	A0A182RJJ6	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.746
A0A182R7A9	A0A182RPC3	A0A182R7A9	A0A182RPC3	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.607
A0A182R7K5	A0A182R7K7	A0A182R7K5	A0A182R7K7	Glutathione transferase microsomal.	Glutathione transferase microsomal.	0.425
A0A182R7K5	A0A182RAT9	A0A182R7K5	A0A182RAT9	Glutathione transferase microsomal.	Glutathione S-transferase.	0.505
A0A182R7K5	A0A182RH80	A0A182R7K5	A0A182RH80	Glutathione transferase microsomal.	Glutathione S-transferase; Belongs to the GST superfamily.	0.505
A0A182R7K5	A0A182RIU5	A0A182R7K5	A0A182RIU5	Glutathione transferase microsomal.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.545
A0A182R7K5	A0A182RJJ6	A0A182R7K5	A0A182RJJ6	Glutathione transferase microsomal.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.493
A0A182R7K5	A0A182RM19	A0A182R7K5	A0A182RM19	Glutathione transferase microsomal.	Glutathione S-transferase; Belongs to the GST superfamily.	0.493
A0A182R7K5	A0A182RPC3	A0A182R7K5	A0A182RPC3	Glutathione transferase microsomal.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.493
A0A182R7K5	A0A182RQ85	A0A182R7K5	A0A182RQ85	Glutathione transferase microsomal.	Glutathione S-transferase.	0.505
A0A182R7K5	A0A182RRC4	A0A182R7K5	A0A182RRC4	Glutathione transferase microsomal.	Glutathione transferase microsomal.	0.518
A0A182R7K5	A0A182RRD4	A0A182R7K5	A0A182RRD4	Glutathione transferase microsomal.	Glutathione S-transferase; Belongs to the GST superfamily.	0.467
A0A182R7K5	A0A182RRD5	A0A182R7K5	A0A182RRD5	Glutathione transferase microsomal.	Glutathione S-transferase.	0.480
A0A182R7K5	A0A182RSI4	A0A182R7K5	A0A182RSI4	Glutathione transferase microsomal.	Glutathione S-transferase; Belongs to the GST superfamily.	0.505