(61 nodes) TGF-beta signaling pathway network (Anopheles funestus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182R406	Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
	A0A182R345	Homeobox domain-containing protein. (499 aa)
	A0A182R4R1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa)
	A0A182R7S1	Serine/threonine-protein phosphatase. (309 aa)
	A0A182R7X4	Uncharacterized protein. (1476 aa)
	A0A182R9P8	Uncharacterized protein. (594 aa)
	A0A182RAU9	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
	A0A182RB24	BHLH domain-containing protein. (151 aa)
	A0A182RC56	BHLH domain-containing protein. (232 aa)
	A0A182RCE7	TGF_BETA_2 domain-containing protein. (346 aa)
	A0A182RCR2	SNAPIN protein homolog; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. (128 aa)
	A0A182REX0	Mothers against decapentaplegic homolog. (512 aa)
	A0A182RF69	Uncharacterized protein. (2197 aa)
	A0A182RFJ7	TGF_BETA_2 domain-containing protein. (573 aa)
	A0A182RG65	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (395 aa)
	A0A182RH81	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
	A0A182RKX5	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1412 aa)
	A0A182RLK5	Uncharacterized protein. (948 aa)
	A0A182RMH9	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (985 aa)
	A0A182RMT4	TGF_BETA_2 domain-containing protein. (442 aa)
	A0A182RQ56	E2F_TDP domain-containing protein. (403 aa)
	A0A182RQ69	CTCK domain-containing protein. (605 aa)
	A0A182RQD0	TGF_BETA_2 domain-containing protein. (59 aa)
	A0A182RQU2	Meis_PKNOX_N domain-containing protein. (267 aa)
	A0A182RR40	Uncharacterized protein. (1049 aa)
	A0A182RS48	DAN domain-containing protein. (171 aa)
	A0A182RT16	Uncharacterized protein. (344 aa)
	A0A182RU24	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (558 aa)
	A0A182RVG2	TGF_BETA_2 domain-containing protein. (422 aa)
	A0A182RVK0	BHLH domain-containing protein. (101 aa)
	A0A182RWC0	Mothers against decapentaplegic homolog. (517 aa)
	A0A182RWI2	CULLIN_2 domain-containing protein; Belongs to the cullin family. (778 aa)
	A0A182RWJ7	FYVE-type domain-containing protein. (1397 aa)
	A0A182RWY3	Uncharacterized protein. (590 aa)
	A0A182RX16	RING-type domain-containing protein. (109 aa)
	A0A182RXM4	Uncharacterized protein. (1198 aa)
	A0A182RZ90	Uncharacterized protein. (2492 aa)
	A0A182RZJ7	Uncharacterized protein. (506 aa)
	A0A4Y0ASW2	BHLH domain-containing protein. (251 aa)
	A0A4Y0AXI8	MH2 domain-containing protein. (267 aa)
	A0A4Y0B378	Homeobox domain-containing protein. (514 aa)
	A0A4Y0B7U6	Mothers against decapentaplegic homolog. (492 aa)
	A0A4Y0B9R1	Mothers against decapentaplegic homolog. (498 aa)
	A0A4Y0BGY2	Uncharacterized protein. (399 aa)
	A0A4Y0BH78	Uncharacterized protein. (491 aa)
	A0A4Y0BHG6	Uncharacterized protein. (1397 aa)
	A0A4Y0BHG8	CTCK domain-containing protein. (281 aa)
	A0A4Y0BHY9	Uncharacterized protein. (720 aa)
	A0A4Y0BIQ7	Uncharacterized protein. (459 aa)
	A0A4Y0BJ79	PLAC domain-containing protein. (692 aa)
	A0A4Y0BJB2	Uncharacterized protein. (1404 aa)
	A0A4Y0BJZ0	Uncharacterized protein. (717 aa)
	A0A4Y0BK50	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (647 aa)
	A0A4Y0BKD1	Uncharacterized protein. (4114 aa)
	A0A4Y0BKH6	Uncharacterized protein; Belongs to the chordin family. (991 aa)
	A0A4Y0BLH8	BHLH domain-containing protein. (1082 aa)
	A0A4Y0BLS3	Uncharacterized protein. (192 aa)
	A0A4Y0BMS1	PLAC domain-containing protein. (804 aa)
	A0A4Y0BNL9	Uncharacterized protein. (998 aa)
	A0A4Y0BQ60	Mothers against decapentaplegic homolog. (772 aa)
	A0A4Y0BRV6	Uncharacterized protein. (207 aa)

Your Current Organism:

Anopheles funestus

NCBI taxonomy Id: 62324
Other names: A. funestus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182R345	A0A182REX0	Homeobox domain-containing protein.	Mothers against decapentaplegic homolog.	0.929
A0A182R345	A0A182RWC0	Homeobox domain-containing protein.	Mothers against decapentaplegic homolog.	0.640
A0A182R345	A0A4Y0AXI8	Homeobox domain-containing protein.	MH2 domain-containing protein.	0.929
A0A182R345	A0A4Y0B7U6	Homeobox domain-containing protein.	Mothers against decapentaplegic homolog.	0.640
A0A182R345	A0A4Y0B9R1	Homeobox domain-containing protein.	Mothers against decapentaplegic homolog.	0.640
A0A182R345	A0A4Y0BNL9	Homeobox domain-containing protein.	Uncharacterized protein.	0.629
A0A182R345	A0A4Y0BQ60	Homeobox domain-containing protein.	Mothers against decapentaplegic homolog.	0.644
A0A182R406	A0A182R4R1	Uncharacterized protein; Belongs to the SKP1 family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.431
A0A182R406	A0A182R7S1	Uncharacterized protein; Belongs to the SKP1 family.	Serine/threonine-protein phosphatase.	0.837
A0A182R406	A0A182R9P8	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.695
A0A182R406	A0A182RAU9	Uncharacterized protein; Belongs to the SKP1 family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.431
A0A182R406	A0A182RF69	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.520
A0A182R406	A0A182RG65	Uncharacterized protein; Belongs to the SKP1 family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.510
A0A182R406	A0A182RH81	Uncharacterized protein; Belongs to the SKP1 family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.431
A0A182R406	A0A182RKX5	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.431
A0A182R406	A0A182RLK5	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.520
A0A182R406	A0A182RMH9	Uncharacterized protein; Belongs to the SKP1 family.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.431
A0A182R406	A0A182RQ56	Uncharacterized protein; Belongs to the SKP1 family.	E2F_TDP domain-containing protein.	0.741
A0A182R406	A0A182RR40	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.780
A0A182R406	A0A182RS48	Uncharacterized protein; Belongs to the SKP1 family.	DAN domain-containing protein.	0.407