(30 nodes) Detoxification of Reactive Oxygen Species, and DJ-1/PfpI network (Caenorhabditis briggsae)

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second shell of interactors

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Predicted Interactions

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Your Input:
	glrx-21	Protein CBR-GLRX-21. (119 aa)
	sod-5	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (157 aa)
	CBG01477	Protein CBG01477. (372 aa)
	gpx-6	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
	prdx-2	Protein CBR-PRDX-2. (195 aa)
	nsy-1	Protein CBR-NSY-1. (1577 aa)
	catp-6	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1172 aa)
	trxr-1	Protein CBR-TRXR-1. (667 aa)
	trxr-2	Protein CBR-TRXR-2. (515 aa)
	djr-1.1	Protein CBR-DJR-1.1. (187 aa)
	djr-1.2	Protein CBR-DJR-1.2. (192 aa)
	Cbr-gpn-1	Protein CBR-GPN-1; Belongs to the glypican family. (1442 aa)
	CBG08487	Protein CBG08487. (279 aa)
	trx-2	Protein CBR-TRX-2. (145 aa)
	sod-4	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (190 aa)
	sod-1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Required for normal brood size. May be involved in regulating mpk-1 phosphorylation downstream of phosphatase ptp-2 during oocyte maturation. Belongs to the Cu-Zn superoxide dismutase family. (180 aa)
	CBG11504	Protein CBG11504. (1007 aa)
	sod-2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
	trx-1	Thioredoxin; Belongs to the thioredoxin family. (121 aa)
	msra-1	Protein CBG13148. (207 aa)
	trx-4	Thioredoxin; Belongs to the thioredoxin family. (107 aa)
	CBG14973	Protein CBG14973. (109 aa)
	prdx-3	Protein CBR-PRDX-3. (228 aa)
	CBG18185	Protein CBG18185. (63 aa)
	mpst-5	Protein CBR-MPST-6. (300 aa)
	ctl-1	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (547 aa)
	ctl-2	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (500 aa)
	CBG20880	Protein CBG20880. (596 aa)
	glrx-10	Protein CBR-GLRX-10. (105 aa)
	CBG06906	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (152 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG01477	ctl-1	A8WQL3	A8XYN6	Protein CBG01477.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.949
CBG01477	ctl-2	A8WQL3	A8XYN7	Protein CBG01477.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.949
CBG01477	djr-1.1	A8WQL3	A8X3W8	Protein CBG01477.	Protein CBR-DJR-1.1.	0.819
CBG01477	djr-1.2	A8WQL3	A8X3W9	Protein CBG01477.	Protein CBR-DJR-1.2.	0.819
CBG01477	msra-1	A8WQL3	A8XH63	Protein CBG01477.	Protein CBG13148.	0.499
CBG06906	CBG08487	G2J6L0	A8X6P1	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBG08487.	0.591
CBG06906	CBG14973	G2J6L0	A8XL46	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBG14973.	0.591
CBG06906	CBG20880	G2J6L0	A8XYV3	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBG20880.	0.402
CBG06906	Cbr-gpn-1	G2J6L0	A8X454	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBR-GPN-1; Belongs to the glypican family.	0.554
CBG06906	ctl-1	G2J6L0	A8XYN6	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.678
CBG06906	ctl-2	G2J6L0	A8XYN7	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.678
CBG06906	gpx-6	G2J6L0	A8WRC1	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.402
CBG06906	msra-1	G2J6L0	A8XH63	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBG13148.	0.954
CBG06906	sod-2	G2J6L0	A8XGF6	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.640
CBG06906	trx-1	G2J6L0	A8XGT0	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Thioredoxin; Belongs to the thioredoxin family.	0.699
CBG06906	trx-2	G2J6L0	A8X8R6	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBR-TRX-2.	0.481
CBG06906	trx-4	G2J6L0	A8XL45	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Thioredoxin; Belongs to the thioredoxin family.	0.699
CBG06906	trxr-1	G2J6L0	A8X1Q8	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBR-TRXR-1.	0.454
CBG06906	trxr-2	G2J6L0	A8X3A1	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	Protein CBR-TRXR-2.	0.454
CBG08487	CBG06906	A8X6P1	G2J6L0	Protein CBG08487.	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.	0.591