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hrpu-1 hrpu-1 rnp-5 rnp-5 thoc-1 thoc-1 CBG24318 CBG24318 thoc-5 thoc-5 CBG24958 CBG24958 uaf-2 uaf-2 hel-1 hel-1 smg-8 smg-8 CBG02037 CBG02037 cey-2.1 cey-2.1 Cbr-rha-1 Cbr-rha-1 rsp-7 rsp-7 ptb-1 ptb-1 rsp-2 rsp-2 rsp-1 rsp-1 rsp-5 rsp-5 CBG02575 CBG02575 rsp-4 rsp-4 rsp-3 rsp-3 CBG04018 CBG04018 smg-5 smg-5 nxt-1 nxt-1 pabp-2 pabp-2 smg-9 smg-9 CBG04561 CBG04561 CBG04575 CBG04575 nxf-2 nxf-2 nxf-1 nxf-1 CBG04754 CBG04754 CBG05145 CBG05145 hrp-1 hrp-1 CBG05376 CBG05376 hrpf-2 hrpf-2 smg-3 smg-3 aly-3 aly-3 etr-1 etr-1 smg-2 smg-2 thoc-2 thoc-2 pnn-1 pnn-1 CBG09828 CBG09828 CBG10243 CBG10243 CBG10223 CBG10223 hrpl-1 hrpl-1 cey-2.2 cey-2.2 CBG12064 CBG12064 acin-1 acin-1 sup-46 sup-46 CBG12229 CBG12229 thoc-3 thoc-3 hrpk-1 hrpk-1 ncbp-1 ncbp-1 ztf-4 ztf-4 fust-1 fust-1 CBG13298 CBG13298 rsp-8 rsp-8 CBG13835 CBG13835 CBG14713 CBG14713 Cbr-cey-2 Cbr-cey-2 CBG15138 CBG15138 smg-6 smg-6 CBG15683 CBG15683 hrp-2 hrp-2 CBG15999 CBG15999 CBG16453 CBG16453 CBG16454 CBG16454 rsp-6 rsp-6 rnp-4 rnp-4 CBG18550 CBG18550 mag-1 mag-1 CBG19371 CBG19371 CBG19556 CBG19556 CBG19557 CBG19557 CBG19634 CBG19634 CBG19980 CBG19980 CBG20155 CBG20155 CBG20364 CBG20364 CBG20393 CBG20393 CBG20414 CBG20414 CBG20685 CBG20685 CBG21777 CBG21777 aly-1 aly-1 CBG22191 CBG22191 ncbp-2 ncbp-2 thoc-7 thoc-7 CBG25779 CBG25779 CBG25982 CBG25982 CBG21776 CBG21776 Cbr-thoc-3.2 Cbr-thoc-3.2 uaf-1 uaf-1 smg-1 smg-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hrpu-1Protein CBG23721. (1725 aa)
rnp-5Protein CBR-RNP-5. (293 aa)
thoc-1Protein CBR-THOC-1. (730 aa)
CBG24318Protein CBG24318. (724 aa)
thoc-5Protein CBG24679. (594 aa)
CBG24958Protein CBG24958. (302 aa)
uaf-2Protein CBR-UAF-2. (281 aa)
hel-1Protein CBR-HEL-1. (424 aa)
smg-8Protein smg-8; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes (By similarity). (871 aa)
CBG02037Protein CBG02037. (260 aa)
cey-2.1Protein CBG02238. (263 aa)
Cbr-rha-1Protein CBR-RHA-1. (1402 aa)
rsp-7Protein CBR-RSP-7. (489 aa)
ptb-1Protein CBR-PTB-1. (610 aa)
rsp-2Protein CBR-RSP-2. (256 aa)
rsp-1Protein CBR-RSP-1. (304 aa)
rsp-5Protein CBR-RSP-5. (150 aa)
CBG02575Protein CBG02575. (316 aa)
rsp-4Protein CBR-RSP-4. (125 aa)
rsp-3Protein CBR-RSP-3. (258 aa)
CBG04018Protein CBG04018; Belongs to the DEAD box helicase family. (393 aa)
smg-5Protein CBR-SMG-5. (551 aa)
nxt-1Protein CBR-NXT-1. (139 aa)
pabp-2Protein CBR-PABP-2. (205 aa)
smg-9Protein smg-9; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Probable component of kinase complex containing smg-1 and recruited to stalled ribosomes (By similarity). (382 aa)
CBG04561Protein FAM50 homolog; Belongs to the FAM50 family. (326 aa)
CBG04575Protein CBG04575. (323 aa)
nxf-2Protein CBR-NXF-2. (399 aa)
nxf-1Protein CBR-NXF-1. (619 aa)
CBG04754Protein CBG04754. (325 aa)
CBG05145Protein CBG05145; Belongs to the DEAD box helicase family. (400 aa)
hrp-1Protein CBR-HRP-1. (366 aa)
CBG05376Protein CBG05376. (182 aa)
hrpf-2Protein CBR-HRPF-2. (606 aa)
smg-3Protein CBR-SMG-3. (1141 aa)
aly-3Protein CBR-ALY-3. (240 aa)
etr-1Protein CBR-ETR-1. (643 aa)
smg-2Protein CBR-SMG-2. (1051 aa)
thoc-2Protein CBR-THOC-2. (1443 aa)
pnn-1Protein CBG09489. (367 aa)
CBG09828Protein CBG09828. (338 aa)
CBG10243Protein CBG10243. (387 aa)
CBG10223Protein CBG10223. (187 aa)
hrpl-1Protein CBG11180. (604 aa)
cey-2.2Protein CBG11894. (258 aa)
CBG12064Serrate RNA effector molecule homolog; Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA- mediated gene silencing (RNAi) by miRNAs (By similarity). Belongs to the ARS2 family. (715 aa)
acin-1Protein CBR-ACIN-1. (575 aa)
sup-46Protein CBG12231. (463 aa)
CBG12229Protein CBG12229. (165 aa)
thoc-3Protein CBR-THOC-3.1. (146 aa)
hrpk-1Protein CBG12588. (398 aa)
ncbp-1Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-1 does not bind directly capped RNAs (m7GpppG- capped RNA) but is required to stabilize the movement of the N-terminal loop of ncbp-2 and lock the CBC into a high affinity cap-binding state with the c [...] (793 aa)
ztf-4Protein CBR-ZTF-4. (368 aa)
fust-1Protein CBR-FUST-1. (433 aa)
CBG13298Protein CBG13298. (178 aa)
rsp-8Protein CBR-RSP-8. (298 aa)
CBG13835Protein CBG13835. (355 aa)
CBG14713Protein CBG14713. (113 aa)
Cbr-cey-2Protein CBR-CEY-2. (265 aa)
CBG15138Protein CBG15138. (300 aa)
smg-6Protein CBR-SMG-6. (773 aa)
CBG15683Protein CBG15683. (251 aa)
hrp-2Protein CBR-HRP-2. (626 aa)
CBG15999Protein CBG15999. (303 aa)
CBG16453Protein CBG16453. (104 aa)
CBG16454Protein CBG16454. (389 aa)
rsp-6Protein CBR-RSP-6. (173 aa)
rnp-4RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (142 aa)
CBG18550Protein CBG18550. (805 aa)
mag-1Protein CBR-MAG-1. (153 aa)
CBG19371Protein CBG19371. (462 aa)
CBG19556Protein CBG19556. (562 aa)
CBG19557Protein CBG19557. (494 aa)
CBG19634Zinc finger Ran-binding domain-containing protein 2. (342 aa)
CBG19980Protein CBG19980. (213 aa)
CBG20155Protein CBG20155. (170 aa)
CBG20364Protein CBG20364. (241 aa)
CBG20393Protein CBG20393. (622 aa)
CBG20414Protein CBG20414. (335 aa)
CBG20685Protein CBG20685. (445 aa)
CBG21777Protein CBG21777. (183 aa)
aly-1Protein CBR-ALY-1. (227 aa)
CBG22191Protein CBG22191. (656 aa)
ncbp-2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap stru [...] (157 aa)
thoc-7Protein CBG22401. (208 aa)
CBG25779Protein CBG25779. (821 aa)
CBG25982Protein CBG25982. (310 aa)
CBG21776Protein CBG21776. (389 aa)
Cbr-thoc-3.2Protein CBR-THOC-3.2. (185 aa)
uaf-1Splicing factor U2AF 65 kDa subunit; Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity). (488 aa)
smg-1Serine/threonine-protein kinase smg-1; Serine/threonine protein kinase involved in mRNA surveillance. Recognizes the substrate consensus sequence [ST]-Q. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating smg-2 (By similarity); Belongs to the PI3/PI4-kinase family. (2313 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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