STRINGSTRING
bro-1 bro-1 CBG24597 CBG24597 CBG00580 CBG00580 CBG01993 CBG01993 CBG02118 CBG02118 pqm-1 pqm-1 prmt-9 prmt-9 sir-2.4 sir-2.4 rnt-1 rnt-1 CBG05019 CBG05019 CBG05575 CBG05575 par-5 par-5 CBG07171 CBG07171 CBG07153 CBG07153 CBG07150 CBG07150 CBG07149 CBG07149 nfyb-1 nfyb-1 nfyc-1 nfyc-1 rpoa-49 rpoa-49 elt-3 elt-3 CBG07952 CBG07952 hda-11 hda-11 end-1 end-1 end-3.1 end-3.1 end-3.2 end-3.2 CBG12020 CBG12020 CBG12823 CBG12823 daf-16 daf-16 let-381 let-381 prmt-1 prmt-1 egl-18 egl-18 elt-6 elt-6 nfya-1 nfya-1 CBG15913 CBG15913 elt-2 elt-2 ftt-2 ftt-2 pal-1 pal-1 srw-1 srw-1 CBG18572 CBG18572 CBG18573 CBG18573 hsf-1 hsf-1 CBG19636 CBG19636 hda-10 hda-10 CBG20801 CBG20801 CBG21496 CBG21496 CBG22824 CBG22824 CBG25455 CBG25455 CBG25456 CBG25456 CBG28094 CBG28094 CBG26056 CBG26056 CBG07229 CBG07229 CBG08811 CBG08811 CBG26098 CBG26098 CBG24924 CBG24924 pes-1 pes-1 sir-2.1 sir-2.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bro-1Protein CBR-BRO-1. (155 aa)
CBG24597Protein CBG24597. (370 aa)
CBG00580Protein CBG00580. (490 aa)
CBG01993Protein CBG01993. (281 aa)
CBG02118Protein CBG02118. (891 aa)
pqm-1Protein CBR-PQM-1. (301 aa)
prmt-9Protein CBR-PRMT-3. (669 aa)
sir-2.4Protein CBR-SIR-2.4. (324 aa)
rnt-1Protein CBR-RNT-1. (312 aa)
CBG05019Protein CBG05019. (573 aa)
CBG05575Protein CBG05575. (166 aa)
par-5Protein CBR-PAR-5; Belongs to the 14-3-3 family. (248 aa)
CBG07171Protein CBG07171. (558 aa)
CBG07153Protein CBG07153. (613 aa)
CBG07150Protein CBG07150. (647 aa)
CBG07149Protein CBG07149. (568 aa)
nfyb-1Protein CBR-NFYB-1. (531 aa)
nfyc-1Protein CBR-NFYC-1. (325 aa)
rpoa-49Protein CBG07002. (430 aa)
elt-3Protein CBR-ELT-3. (304 aa)
CBG07952Protein CBG07952. (523 aa)
hda-11Protein CBR-HDAC-11. (176 aa)
end-1Protein CBR-END-1. (210 aa)
end-3.1Protein CBR-END-3. (253 aa)
end-3.2Protein CBG11404. (248 aa)
CBG12020Protein CBG12020. (408 aa)
CBG12823Protein CBG12823. (107 aa)
daf-16Protein CBR-DAF-16. (497 aa)
let-381Protein CBR-LET-381. (363 aa)
prmt-1Protein CBR-PRMT-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (345 aa)
egl-18Protein CBR-EGL-18. (419 aa)
elt-6Protein CBR-ELT-6. (405 aa)
nfya-1Protein CBR-NFYA-1. (564 aa)
CBG15913Protein CBG15913. (166 aa)
elt-2Protein CBR-ELT-2. (445 aa)
ftt-2Protein CBR-FTT-2; Belongs to the 14-3-3 family. (248 aa)
pal-1Homeobox protein pal-1; Transcriptional activator. Interacts with promoter regions for tbx-8.9, tbx-9, elt-1, hnd-1, scrt-1, and vab-7 genes. Binds the sequence ATTTATGAC. Binds to the enhancer region of the hlh-1 gene promoter during embryonic body wall muscle development. Activates the gene for mab-5 in embryo development. Necessary for vab-7 expression in C blastomeres in the posterior of embryos. Required for posterior V6 neuroectoblast cell fate specification during postembryonic neurogenesis (patterning) which generates the characteristic ray lineage during male tail development. [...] (271 aa)
srw-1Protein CBR-SRW-1. (172 aa)
CBG18572Protein CBG18572. (356 aa)
CBG18573Protein CBG18573. (123 aa)
hsf-1Protein CBR-HSF-1. (504 aa)
CBG19636Protein CBG19636. (554 aa)
hda-10Protein CBR-HDA-6. (506 aa)
CBG20801Protein CBG20801. (791 aa)
CBG21496Protein CBG21496. (94 aa)
CBG22824Protein CBG22824. (362 aa)
CBG25455Protein CBG25455. (422 aa)
CBG25456Protein CBG25456. (219 aa)
CBG28094Protein CBG28094. (88 aa)
CBG26056Protein CBG26056. (537 aa)
CBG07229Protein CBG07229. (411 aa)
CBG08811Protein CBG08811. (200 aa)
CBG26098Protein CBG26098. (333 aa)
CBG24924Protein CBG24924. (389 aa)
pes-1Protein CBR-PES-1. (172 aa)
sir-2.1NAD-dependent protein deacetylase sir-2.1; NAD-dependent deacetylase. Required for a reduction of the 'Lys-16' acetylation of histone H4 (H4K16ac) on dosage-compensated X chromosomes in hermaphrodites. Functions upstream of daf-16 in the insulin-like signaling pathway, promoting daf-16 mediated transcriptional activation and increased life-span. May also regulate life-span independently of daf-16 by modulating the transcription of genes involved in the stress response of the endoplasmic reticulum (ER). Acts upstream of the nicotinic acid metabolism pathway, which may be linked to the r [...] (602 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (16%) [HD]