(22 nodes) Mixed, incl. Transcription factor GATA, and Regulation of gene expression by Hypoxia-inducible Factor network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bro-1	Protein CBR-BRO-1. (155 aa)
	CBG00580	Protein CBG00580. (490 aa)
	pqm-1	Protein CBR-PQM-1. (301 aa)
	prmt-9	Protein CBR-PRMT-3. (669 aa)
	rnt-1	Protein CBR-RNT-1. (312 aa)
	CBG05575	Protein CBG05575. (166 aa)
	CBG07171	Protein CBG07171. (558 aa)
	CBG07150	Protein CBG07150. (647 aa)
	elt-3	Protein CBR-ELT-3. (304 aa)
	end-1	Protein CBR-END-1. (210 aa)
	end-3.1	Protein CBR-END-3. (253 aa)
	end-3.2	Protein CBG11404. (248 aa)
	let-381	Protein CBR-LET-381. (363 aa)
	prmt-1	Protein CBR-PRMT-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (345 aa)
	egl-18	Protein CBR-EGL-18. (419 aa)
	elt-6	Protein CBR-ELT-6. (405 aa)
	elt-2	Protein CBR-ELT-2. (445 aa)
	pal-1	Homeobox protein pal-1; Transcriptional activator. Interacts with promoter regions for tbx-8.9, tbx-9, elt-1, hnd-1, scrt-1, and vab-7 genes. Binds the sequence ATTTATGAC. Binds to the enhancer region of the hlh-1 gene promoter during embryonic body wall muscle development. Activates the gene for mab-5 in embryo development. Necessary for vab-7 expression in C blastomeres in the posterior of embryos. Required for posterior V6 neuroectoblast cell fate specification during postembryonic neurogenesis (patterning) which generates the characteristic ray lineage during male tail development. [...] (271 aa)
	srw-1	Protein CBR-SRW-1. (172 aa)
	CBG18572	Protein CBG18572. (356 aa)
	CBG26056	Protein CBG26056. (537 aa)
	pes-1	Protein CBR-PES-1. (172 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00580	prmt-1	A8WNJ3	A8XGN2	Protein CBG00580.	Protein CBR-PRMT-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.415
CBG00580	rnt-1	A8WNJ3	A8WW51	Protein CBG00580.	Protein CBR-RNT-1.	0.465
CBG05575	CBG18572	A8X067	A8XTL9	Protein CBG05575.	Protein CBG18572.	0.466
CBG05575	egl-18	A8X067	A8XI58	Protein CBG05575.	Protein CBR-EGL-18.	0.487
CBG05575	elt-2	A8X067	A8XQH0	Protein CBG05575.	Protein CBR-ELT-2.	0.552
CBG05575	elt-3	A8X067	A8X4Z2	Protein CBG05575.	Protein CBR-ELT-3.	0.769
CBG05575	elt-6	A8X067	A8XI59	Protein CBG05575.	Protein CBR-ELT-6.	0.487
CBG05575	end-1	A8X067	A8XD31	Protein CBG05575.	Protein CBR-END-1.	0.737
CBG05575	end-3.1	A8X067	A8XD37	Protein CBG05575.	Protein CBR-END-3.	0.691
CBG05575	end-3.2	A8X067	A8XD39	Protein CBG05575.	Protein CBG11404.	0.691
CBG05575	pqm-1	A8X067	A8WT47	Protein CBG05575.	Protein CBR-PQM-1.	0.654
CBG05575	prmt-1	A8X067	A8XGN2	Protein CBG05575.	Protein CBR-PRMT-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.407
CBG05575	srw-1	A8X067	A8XTL5	Protein CBG05575.	Protein CBR-SRW-1.	0.466
CBG07150	prmt-1	A8X3L3	A8XGN2	Protein CBG07150.	Protein CBR-PRMT-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.415
CBG07150	rnt-1	A8X3L3	A8WW51	Protein CBG07150.	Protein CBR-RNT-1.	0.465
CBG07171	prmt-1	A8X3J8	A8XGN2	Protein CBG07171.	Protein CBR-PRMT-1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.415
CBG07171	rnt-1	A8X3J8	A8WW51	Protein CBG07171.	Protein CBR-RNT-1.	0.465
CBG18572	CBG05575	A8XTL9	A8X067	Protein CBG18572.	Protein CBG05575.	0.466
CBG18572	bro-1	A8XTL9	A8WJ65	Protein CBG18572.	Protein CBR-BRO-1.	0.504
CBG18572	rnt-1	A8XTL9	A8WW51	Protein CBG18572.	Protein CBR-RNT-1.	0.629