(37 nodes) Valine, leucine and isoleucine degradation, and Acyl-CoA oxidase network (Caenorhabditis briggsae)

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Predicted Interactions

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Your Input:
	hach-1	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (386 aa)
	acaa-2	Protein CBG24278; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	CBG24740	Protein CBG24740; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
	kat-1	Protein CBR-KAT-1; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	lsy-22	Protein CBR-LSY-22. (306 aa)
	CBG00970	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	CBG00953	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family. (408 aa)
	alh-8	Protein CBR-ALH-8. (523 aa)
	ech-4	Protein CBR-ECH-4. (385 aa)
	CBG02861	Protein CBG02861. (370 aa)
	ech-9	Protein CBR-ECH-9. (448 aa)
	acox-3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (671 aa)
	CBG05550	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (591 aa)
	CBG05595	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (299 aa)
	hacd-1	Protein CBR-HACD-1. (298 aa)
	CBG06885	Protein CBG06885; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
	acdh-9	Protein CBG07125. (409 aa)
	CBG06958	Protein CBG06958. (430 aa)
	dhs-6	Protein CBR-DHS-6. (418 aa)
	CBG07944	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (743 aa)
	ech-7	Protein CBR-ECH-7; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	alh-12	Protein CBR-ALH-12. (499 aa)
	CBG09979	Protein CBG09979; Belongs to the enoyl-CoA hydratase/isomerase family. (286 aa)
	ech-6	Protein CBR-ECH-6; Belongs to the enoyl-CoA hydratase/isomerase family. (288 aa)
	acox-1.5	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (659 aa)
	CBG10094	Protein CBG10094. (297 aa)
	sur-5	Protein CBR-SUR-5. (691 aa)
	CBG12007	Protein CBG12007; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa)
	mce-1	Protein CBR-MCE-1. (140 aa)
	ech-1.2	Protein CBG12562. (755 aa)
	acdh-1	Protein CBR-ACDH-1. (421 aa)
	CBG12664	Protein CBG12664. (420 aa)
	pccb-1	Protein CBR-PCCB-1. (536 aa)
	acox-1.6	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (667 aa)
	acdh-7	Protein CBG15945. (413 aa)
	CBG16139	Protein CBG16139. (309 aa)
	pcca-1	Propionyl-CoA carboxylase alpha chain, mitochondrial; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl- CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl car [...] (738 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00953	CBG00970	A8WP91	A8WP76	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.492
CBG00953	CBG02861	A8WP91	A8WTC7	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG02861.	0.911
CBG00953	CBG05550	A8WP91	A8X049	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.408
CBG00953	CBG06885	A8WP91	A8X3A2	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG06885; Belongs to the thiolase-like superfamily. Thiolase family.	0.972
CBG00953	CBG06958	A8WP91	A8X420	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG06958.	0.737
CBG00953	CBG09979	A8WP91	A8XA31	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG09979; Belongs to the enoyl-CoA hydratase/isomerase family.	0.962
CBG00953	CBG10094	A8WP91	A8XAD6	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG10094.	0.700
CBG00953	CBG12007	A8WP91	A8XEB9	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG12007; Belongs to the enoyl-CoA hydratase/isomerase family.	0.622
CBG00953	CBG16139	A8WP91	A8XP12	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG16139.	0.700
CBG00953	CBG24740	A8WP91	A8WLD3	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG24740; Belongs to the thiolase-like superfamily. Thiolase family.	0.962
CBG00953	acaa-2	A8WP91	A8WKD1	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG24278; Belongs to the thiolase-like superfamily. Thiolase family.	0.974
CBG00953	acdh-7	A8WP91	A8XNF1	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG15945.	0.433
CBG00953	acox-1.6	A8WP91	A8XNA5	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.408
CBG00953	acox-3	A8WP91	A8X001	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.529
CBG00953	alh-12	A8WP91	A8X897	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBR-ALH-12.	0.449
CBG00953	dhs-6	A8WP91	A8X421	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBR-DHS-6.	0.737
CBG00953	ech-1.2	A8WP91	A8XG18	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBG12562.	0.968
CBG00953	ech-4	A8WP91	A8WT03	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBR-ECH-4.	0.817
CBG00953	ech-6	A8WP91	A8XA54	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBR-ECH-6; Belongs to the enoyl-CoA hydratase/isomerase family.	0.962
CBG00953	ech-7	A8WP91	A8X7A3	Probable medium-chain specific acyl-CoA dehydrogenase 2, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family.	Protein CBR-ECH-7; Belongs to the enoyl-CoA hydratase/isomerase family.	0.962