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CBG24506 CBG24506 acly-1 acly-1 bcat-1 bcat-1 bckd-1b bckd-1b pck-1 pck-1 dlat-2 dlat-2 sucg-1 sucg-1 CBG00820 CBG00820 Cbr-sdhb-1 Cbr-sdhb-1 sdhb-1 sdhb-1 Cbr-gpd-1 Cbr-gpd-1 tald-1 tald-1 pfk-1.1 pfk-1.1 dbt-1 dbt-1 enol-1 enol-1 ldh-1 ldh-1 sdhd-1 sdhd-1 CBG02845 CBG02845 CBG02267 CBG02267 tkt-1 tkt-1 CBG03574 CBG03574 idhg-2 idhg-2 CBG04059 CBG04059 fbp-1 fbp-1 ddo-2 ddo-2 dlat-1 dlat-1 got-2.2 got-2.2 CBG05537 CBG05537 ddo-1 ddo-1 gspd-1 gspd-1 pyk-2 pyk-2 CBG06989 CBG06989 sucl-1 sucl-1 gpi-1 gpi-1 CBG08614 CBG08614 CBG09091 CBG09091 CBG09080 CBG09080 aldo-2 aldo-2 CBG09051 CBG09051 fum-1 fum-1 pfkb-1.2 pfkb-1.2 acly-2 acly-2 CBG09990 CBG09990 pfkb-1.1 pfkb-1.1 pgk-1 pgk-1 sdha-2 sdha-2 idha-1 idha-1 ipgm-1 ipgm-1 CBG12799 CBG12799 pdha-1 pdha-1 CBG15215 CBG15215 mdh-2 mdh-2 sucl-2 sucl-2 CBG15299 CBG15299 aldo-1 aldo-1 CBG15343 CBG15343 bckd-1a bckd-1a idhb-1 idhb-1 got-1.2 got-1.2 Cbr-got-1.3 Cbr-got-1.3 CBG16623 CBG16623 rpia-1 rpia-1 pyk-1 pyk-1 aco-1 aco-1 idh-2 idh-2 CBG17449 CBG17449 suca-1 suca-1 CBG17504 CBG17504 CBG17632 CBG17632 idhg-1 idhg-1 mdh-1 mdh-1 CBG19118 CBG19118 pfk-1.2 pfk-1.2 hxk-1 hxk-1 ddo-3 ddo-3 tpi-1 tpi-1 pdhb-1 pdhb-1 CBG21525 CBG21525 dld-1 dld-1 idh-1 idh-1 got-2.1 got-2.1 sdha-1 sdha-1 aco-2 aco-2 ogdh-2 ogdh-2 pyc-1 pyc-1 CBG25625 CBG25625 CBG26121 CBG26121 CBG00293 CBG00293 pck-2 pck-2 dlst-1 dlst-1 pat-4 pat-4 gpd-3.2 gpd-3.2 gpd-3.1 gpd-3.1 mev-1 mev-1 cts-1 cts-1 ogdh-1 ogdh-1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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CBG24506Protein CBG24506. (202 aa)
acly-1ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1106 aa)
bcat-1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (414 aa)
bckd-1bProtein CBR-TAG-173. (221 aa)
pck-1Protein CBG00466. (648 aa)
dlat-2Protein CBG00405. (338 aa)
sucg-1Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (415 aa)
CBG00820Glyceraldehyde-3-phosphate dehydrogenase. (341 aa)
Cbr-sdhb-1Protein CBG00873. (442 aa)
sdhb-1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (282 aa)
Cbr-gpd-1Glyceraldehyde-3-phosphate dehydrogenase. (341 aa)
tald-1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (338 aa)
pfk-1.1ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (831 aa)
dbt-1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
enol-1Protein CBR-ENOL-1. (434 aa)
ldh-1L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
sdhd-1Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (145 aa)
CBG02845Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (312 aa)
CBG02267Protein CBG02267; Belongs to the phosphohexose mutase family. (570 aa)
tkt-1Protein CBR-TKT-1. (618 aa)
CBG03574Protein CBG03574; Belongs to the phosphohexose mutase family. (574 aa)
idhg-2Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
CBG04059Protein CBG04059. (504 aa)
fbp-1Protein CBR-FBP-1; Belongs to the FBPase class 1 family. (397 aa)
ddo-2D-aspartate oxidase 2; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA. May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells. Belongs to the DAMOX/DASOX family. (331 aa)
dlat-1Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (507 aa)
got-2.2Aspartate aminotransferase. (414 aa)
CBG05537Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (389 aa)
ddo-1Protein CBR-DDO-1. (337 aa)
gspd-1Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (524 aa)
pyk-2Pyruvate kinase; Belongs to the pyruvate kinase family. (511 aa)
CBG06989Protein CBG06989. (842 aa)
sucl-1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (322 aa)
gpi-1Glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
CBG08614Protein CBG08614. (307 aa)
CBG09091Protein CBG09091. (348 aa)
CBG09080Protein CBG09080. (387 aa)
aldo-2Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (366 aa)
CBG09051Protein CBG09051. (139 aa)
fum-1Protein CBR-FUM-1. (491 aa)
pfkb-1.2Protein CBG09461. (457 aa)
acly-2ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1111 aa)
CBG09990Mannose-6-phosphate isomerase. (409 aa)
pfkb-1.1Protein CBG10830. (461 aa)
pgk-1Phosphoglycerate kinase. (416 aa)
sdha-2Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa)
idha-1Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (360 aa)
ipgm-1Protein CBG12654. (521 aa)
CBG12799Protein CBG12799. (180 aa)
pdha-1Protein CBR-PDHA-1. (300 aa)
CBG15215Protein CBG15215. (174 aa)
mdh-2Malate dehydrogenase. (341 aa)
sucl-2Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (321 aa)
CBG15299Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (229 aa)
aldo-1Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (365 aa)
CBG15343Protein CBG15343. (298 aa)
bckd-1a2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (432 aa)
idhb-1Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa)
got-1.2Aspartate aminotransferase. (408 aa)
Cbr-got-1.3Protein CBR-GOT-1.3. (397 aa)
CBG16623Protein CBG16623. (446 aa)
rpia-1Protein CBR-RPIA-1. (251 aa)
pyk-1Pyruvate kinase; Belongs to the pyruvate kinase family. (974 aa)
aco-1Protein CBR-ACO-1; Belongs to the aconitase/IPM isomerase family. (909 aa)
idh-2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (435 aa)
CBG17449Protein CBG17449. (368 aa)
suca-1Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (435 aa)
CBG17504Protein CBG17504. (353 aa)
CBG176326-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
idhg-1Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
mdh-1Malate dehydrogenase. (336 aa)
CBG19118Protein CBG19118. (468 aa)
pfk-1.2Protein CBG19122. (758 aa)
hxk-1Phosphotransferase. (491 aa)
ddo-3Protein CBR-DDO-3. (383 aa)
tpi-1Triosephosphate isomerase. (247 aa)
pdhb-1Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (352 aa)
CBG215256-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (258 aa)
dld-1Dihydrolipoyl dehydrogenase. (495 aa)
idh-1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
got-2.1Aspartate aminotransferase. (419 aa)
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (645 aa)
aco-2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
ogdh-2Protein CBG23406. (891 aa)
pyc-1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1166 aa)
CBG25625Protein CBG25625. (220 aa)
CBG26121Protein CBG26121. (157 aa)
CBG00293Protein CBG00293. (158 aa)
pck-2Protein CBG08279. (653 aa)
dlst-1Protein CBR-DLST-1. (474 aa)
pat-42-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (424 aa)
gpd-3.2Glyceraldehyde-3-phosphate dehydrogenase 2; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
gpd-3.1Glyceraldehyde-3-phosphate dehydrogenase 3.1; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
mev-1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Mediates resistance to enteropathogenic E.coli infection (By similarity); Belongs to the cytochrome b560 family. (184 aa)
cts-1Probable citrate synthase, mitochondrial. (468 aa)
ogdh-12-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (1027 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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