(33 nodes) Glycine, serine and threonine metabolism, and One carbon pool by folate network (Caenorhabditis briggsae)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	CBG01775	Protein CBG01775. (264 aa)
	pdpr-1	Protein CBG02210. (885 aa)
	agxt-1	Serine--pyruvate aminotransferase. (413 aa)
	gldc-1	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (985 aa)
	pacs-1	Protein CBG03675. (422 aa)
	CBG05074	Protein CBG05074. (399 aa)
	CBG05075	Protein CBG05075. (387 aa)
	alh-3	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
	gcsh-1	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (148 aa)
	adss-1	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (435 aa)
	gcst-1	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa)
	CBG10863	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1019 aa)
	gcsh-2	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (146 aa)
	CBG12218	Protein CBG12218. (228 aa)
	dhfr-1	Protein CBG12356; Belongs to the dihydrofolate reductase family. (189 aa)
	CBG12888	Protein CBG12888; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
	CBG12961	Protein CBG12961. (278 aa)
	daao-1	D-amino-acid oxidase; Catalyzes oxidative deamination of D-amino acids, in particular D-alanine, and could be responsible for the degradation of diet-derived D-alanine in the intestine. Acts on a variety of D-amino acids with greater preference towards those with basic and aromatic groups followed by those bearing neutral groups. Has no activity against acidic D-amino acids, L-amino acids or N-methyl-L-aspartic acid. May play a role in egg-laying events and early development. (329 aa)
	CBG14872	Protein CBG14872. (281 aa)
	CBG15194	Protein CBG15194. (458 aa)
	dao-3	Protein CBR-DAO-3. (301 aa)
	atic-1	Protein CBG17698. (615 aa)
	CBG17652	Protein CBG17652. (427 aa)
	ppat-1	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (480 aa)
	pfas-1	Protein CBG18026. (1337 aa)
	tyms-1	Protein CBG20269. (315 aa)
	metr-1	Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). (1273 aa)
	CBG20736	Protein CBG20736; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
	CBG22021	Phosphoserine aminotransferase. (369 aa)
	CBG22093	Protein CBG22093. (857 aa)
	CBG27847	Protein CBG27847. (642 aa)
	adsl-1	Adenylosuccinate lyase; Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (478 aa)
	mel-32	Serine hydroxymethyltransferase; Interconversion of serine and glycine. (511 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG01775	CBG10863	A8WQV3	A8XC59	Protein CBG01775.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.891
CBG01775	CBG17652	A8WQV3	A8XRL7	Protein CBG01775.	Protein CBG17652.	0.887
CBG01775	CBG20736	A8WQV3	A8XYH5	Protein CBG01775.	Protein CBG20736; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.917
CBG01775	CBG22021	A8WQV3	A8Y1C7	Protein CBG01775.	Phosphoserine aminotransferase.	0.998
CBG01775	CBG22093	A8WQV3	A8Y1I3	Protein CBG01775.	Protein CBG22093.	0.414
CBG01775	agxt-1	A8WQV3	A8WSK6	Protein CBG01775.	Serine--pyruvate aminotransferase.	0.926
CBG01775	atic-1	A8WQV3	A8XRH8	Protein CBG01775.	Protein CBG17698.	0.618
CBG01775	gcst-1	A8WQV3	A8X9C1	Protein CBG01775.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.444
CBG01775	gldc-1	A8WQV3	A8WU09	Protein CBG01775.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.520
CBG01775	mel-32	A8WQV3	Q60V73	Protein CBG01775.	Serine hydroxymethyltransferase; Interconversion of serine and glycine.	0.993
CBG01775	pdpr-1	A8WQV3	A8WSA0	Protein CBG01775.	Protein CBG02210.	0.414
CBG01775	ppat-1	A8WQV3	A8XST9	Protein CBG01775.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.684
CBG05074	CBG05075	A8WZ41	A8WZ42	Protein CBG05074.	Protein CBG05075.	0.901
CBG05074	CBG12888	A8WZ41	A8XFU0	Protein CBG05074.	Protein CBG12888; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.940
CBG05074	CBG12961	A8WZ41	A8XGS0	Protein CBG05074.	Protein CBG12961.	0.402
CBG05074	CBG17652	A8WZ41	A8XRL7	Protein CBG05074.	Protein CBG17652.	0.939
CBG05074	CBG22093	A8WZ41	A8Y1I3	Protein CBG05074.	Protein CBG22093.	0.959
CBG05074	agxt-1	A8WZ41	A8WSK6	Protein CBG05074.	Serine--pyruvate aminotransferase.	0.485
CBG05074	daao-1	A8WZ41	A8XJ44	Protein CBG05074.	D-amino-acid oxidase; Catalyzes oxidative deamination of D-amino acids, in particular D-alanine, and could be responsible for the degradation of diet-derived D-alanine in the intestine. Acts on a variety of D-amino acids with greater preference towards those with basic and aromatic groups followed by those bearing neutral groups. Has no activity against acidic D-amino acids, L-amino acids or N-methyl-L-aspartic acid. May play a role in egg-laying events and early development.	0.922
CBG05074	gcsh-1	A8WZ41	A8X4P3	Protein CBG05074.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.435