STRINGSTRING
CBG23610 CBG23610 ell-1 ell-1 CBG03263 CBG03263 hmg-3 hmg-3 rpb-7 rpb-7 ccnk-1 ccnk-1 spt-5 spt-5 leo-1 leo-1 rpap-2 rpap-2 hmg-4 hmg-4 ctr-9 ctr-9 CBG11103 CBG11103 rpb-9 rpb-9 CBG11911 CBG11911 fcp-1 fcp-1 rpb-3 rpb-3 CBG12728 CBG12728 rpb-4 rpb-4 CBG15576 CBG15576 rpb-2 rpb-2 cdk-12 cdk-12 rpb-8 rpb-8 rtfo-1 rtfo-1 cdk-9 cdk-9 tceb-3 tceb-3 rpb-12 rpb-12 eaf-1 eaf-1 cit-1.1 cit-1.1 cit-1.2 cit-1.2 cdc-73 cdc-73 pafo-1 pafo-1 CBG25049 CBG25049 rpb-1 rpb-1 rpb-11 rpb-11 spt-16 spt-16 CBG08373 CBG08373 spt-4 spt-4 emb-5 emb-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG23610Protein CBG23610. (168 aa)
ell-1Protein CBR-ELL-1. (630 aa)
CBG03263Protein CBG03263. (304 aa)
hmg-3FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (689 aa)
rpb-7Protein CBR-RPB-7. (174 aa)
ccnk-1Protein CBG04574; Belongs to the cyclin family. (260 aa)
spt-5Transcription elongation factor SPT5. (1238 aa)
leo-1Protein CBG06074. (439 aa)
rpap-2Protein CBG06841. (433 aa)
hmg-4FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (695 aa)
ctr-9Protein CBG10075. (1263 aa)
CBG11103Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (84 aa)
rpb-9DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (144 aa)
CBG11911Protein CBG11911. (174 aa)
fcp-1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (653 aa)
rpb-3Protein CBR-RPB-3. (280 aa)
CBG12728Protein CBG12728. (463 aa)
rpb-4Protein CBR-RPB-4. (144 aa)
CBG15576Protein CBG15576; Belongs to the SKP1 family. (156 aa)
rpb-2DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1215 aa)
cdk-12Protein CBR-CDTL-7. (642 aa)
rpb-8Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity). (148 aa)
rtfo-1Protein CBG19313. (601 aa)
cdk-9Protein CBR-CDK-9; Belongs to the protein kinase superfamily. (464 aa)
tceb-3Protein CBG20634. (438 aa)
rpb-12Protein CBR-RPB-12. (62 aa)
eaf-1Protein CBR-EAF-1. (255 aa)
cit-1.1Protein CBR-CIT-1.1. (161 aa)
cit-1.2Protein CBR-CIT-1.2. (792 aa)
cdc-73Protein CBG22949. (504 aa)
pafo-1Protein CBG23232. (443 aa)
CBG25049Protein CBG25049. (122 aa)
rpb-1DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...] (1853 aa)
rpb-11Probable DNA-directed RNA polymerase II subunit RPB11; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). (122 aa)
spt-16FACT complex subunit spt-16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment [...] (1034 aa)
CBG08373IWS1-like protein. (497 aa)
spt-4Transcription elongation factor SPT4; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity). (120 aa)
emb-5Suppressor of Ty 6 homolog; May regulate transcriptional elongation by RNA polymerase II. May be required for several aspects of morphogenesis of C.briggsae, including regulation of division in the germline and gut and specification of ventral-uterine precursor cell fate (By similarity). (1521 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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