(20 nodes) Mixed, incl. Adaptation of signaling pathway, and Neuron fate commitment network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	odr-7	Protein CBR-ODR-7. (446 aa)
	ttx-3	Protein CBR-TTX-3. (380 aa)
	cho-1	Protein CBR-CHO-1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (570 aa)
	cfi-1	Protein CBR-CFI-1. (481 aa)
	CBG06777	Protein CBG06777. (308 aa)
	pag-3	Protein CBR-PAG-3. (387 aa)
	unc-3	Protein CBR-UNC-3. (491 aa)
	ceh-10	Protein CBR-CEH-10. (335 aa)
	nhr-239	Protein CBR-NHR-239. (192 aa)
	feh-1	Protein CBR-FEH-1. (723 aa)
	glr-4	Protein CBR-GLR-4. (1007 aa)
	fax-1	Protein CBR-FAX-1. (405 aa)
	lim-4	Protein CBR-LIM-4. (346 aa)
	flh-1	Protein CBG15060. (483 aa)
	unc-86	POU domain protein. (346 aa)
	ceh-43	Protein CBR-CEH-43. (296 aa)
	unc-42	Protein CBR-UNC-42. (269 aa)
	ast-1	Protein CBR-AST-1. (322 aa)
	mec-3	Mechanosensory protein 3; Specifies differentiation of the set of six touch receptor neurons. Binds cooperatively as a heterodimer with unc-86 to sites in the mec-3 gene promoter. (318 aa)
	sra-11	Serpentine receptor class alpha-11; A G protein-coupled receptor required for olfactory imprinting a requisite in ordorant response such as benzaldehyde and isoamylalcohol; Belongs to the nematode receptor-like protein sra family. (343 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG06777	fax-1	A8X320	A8XJF1	Protein CBG06777.	Protein CBR-FAX-1.	0.645
CBG06777	flh-1	A8X320	A8XLB0	Protein CBG06777.	Protein CBG15060.	0.682
CBG06777	odr-7	A8X320	A8WMC0	Protein CBG06777.	Protein CBR-ODR-7.	0.529
ast-1	ceh-43	A8Y133	A8XSY1	Protein CBR-AST-1.	Protein CBR-CEH-43.	0.750
ast-1	nhr-239	A8Y133	A8X9S8	Protein CBR-AST-1.	Protein CBR-NHR-239.	0.404
ast-1	ttx-3	A8Y133	A8WML0	Protein CBR-AST-1.	Protein CBR-TTX-3.	0.642
ast-1	unc-86	A8Y133	A8XP93	Protein CBR-AST-1.	POU domain protein.	0.433
ceh-10	ceh-43	A8X7U3	A8XSY1	Protein CBR-CEH-10.	Protein CBR-CEH-43.	0.671
ceh-10	cfi-1	A8X7U3	A8WWQ1	Protein CBR-CEH-10.	Protein CBR-CFI-1.	0.650
ceh-10	cho-1	A8X7U3	A8WQR8	Protein CBR-CEH-10.	Protein CBR-CHO-1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	0.541
ceh-10	lim-4	A8X7U3	A8XJQ1	Protein CBR-CEH-10.	Protein CBR-LIM-4.	0.651
ceh-10	sra-11	A8X7U3	Q60T36	Protein CBR-CEH-10.	Serpentine receptor class alpha-11; A G protein-coupled receptor required for olfactory imprinting a requisite in ordorant response such as benzaldehyde and isoamylalcohol; Belongs to the nematode receptor-like protein sra family.	0.750
ceh-10	ttx-3	A8X7U3	A8WML0	Protein CBR-CEH-10.	Protein CBR-TTX-3.	0.795
ceh-10	unc-3	A8X7U3	A8X4H7	Protein CBR-CEH-10.	Protein CBR-UNC-3.	0.718
ceh-10	unc-86	A8X7U3	A8XP93	Protein CBR-CEH-10.	POU domain protein.	0.701
ceh-43	ast-1	A8XSY1	A8Y133	Protein CBR-CEH-43.	Protein CBR-AST-1.	0.750
ceh-43	ceh-10	A8XSY1	A8X7U3	Protein CBR-CEH-43.	Protein CBR-CEH-10.	0.671
ceh-43	lim-4	A8XSY1	A8XJQ1	Protein CBR-CEH-43.	Protein CBR-LIM-4.	0.535
ceh-43	ttx-3	A8XSY1	A8WML0	Protein CBR-CEH-43.	Protein CBR-TTX-3.	0.538
ceh-43	unc-86	A8XSY1	A8XP93	Protein CBR-CEH-43.	POU domain protein.	0.560