(60 nodes) Mixed, incl. Notch signaling pathway, and RNA pyrophosphohydrolase activity network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG23974	Protein CBG23974. (894 aa)
	CBG24123	Protein CBG24123. (79 aa)
	CBG00724	Protein CBG00724. (676 aa)
	CBG01049	Protein CBG01049. (177 aa)
	ttr-45	Protein CBR-TTR-45. (140 aa)
	CBG02788	Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (134 aa)
	CBG02544	Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod. (127 aa)
	Cbr-srb-1	Protein CBR-SRB-1. (355 aa)
	CBG03682	Protein CBG03682. (828 aa)
	CBG04293	Protein CBG04293. (807 aa)
	CBG05362	Protein CBG05362. (1336 aa)
	lag-1	Protein CBR-LAG-1. (681 aa)
	CBG05759	Protein CBG05759. (348 aa)
	CBG05755	Protein CBG05755. (300 aa)
	CBG05735	Protein CBG05735. (77 aa)
	CBG06287	Protein CBG06287. (375 aa)
	CBG06537	Protein CBG06537. (354 aa)
	CBG06552	Protein CBG06552. (327 aa)
	lin-12.2	Protein CBR-LIN-12. (1392 aa)
	CBG06829	Protein CBG06829. (987 aa)
	lin-12.1	Protein CBG06951. (1359 aa)
	CBG07041	Protein CBG07041. (439 aa)
	sel-12	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
	CBG08681	Protein CBG08681. (566 aa)
	CBG08639	Protein CBG08639. (604 aa)
	CBG10225	Protein CBG10225. (295 aa)
	CBG10218	Protein CBG10218. (483 aa)
	CBG10877	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (626 aa)
	CBG11254	Protein CBG11254. (148 aa)
	hop-1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
	sup-17	Protein CBR-SUP-17. (920 aa)
	CBG12386	Protein CBG12386. (2855 aa)
	CBG12791	Protein CBG12791. (1127 aa)
	pen-2	Protein CBR-PEN-2. (101 aa)
	CBG13305	Protein CBG13305. (869 aa)
	CBG13609	Protein CBG13609. (372 aa)
	CBG14498	Protein CBG14498. (431 aa)
	pqn-72	Protein CBR-PQN-72. (700 aa)
	CBG15135	Protein CBG15135. (681 aa)
	kpc-1	Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
	CBG15922	Protein CBG15922. (157 aa)
	clec-133.1	Protein CBR-CLEC-133. (171 aa)
	CBG18276	Protein CBG18276. (442 aa)
	cut-6	Protein CBR-CUT-6. (357 aa)
	CBG18681	Protein CBG18681. (217 aa)
	CBG19473	Protein CBG19473. (96 aa)
	CBG19721	Protein CBG19721. (376 aa)
	CBG19858	Protein CBG19858. (1053 aa)
	CBG19956	Protein CBG19956. (1304 aa)
	ttr-55	Protein CBG20293. (159 aa)
	CBG20706	Protein CBG20706. (133 aa)
	CBG20713	Protein CBG20713. (656 aa)
	CBG21295	Protein CBG21295. (1677 aa)
	aph-2	Protein CBR-APH-2. (721 aa)
	aph-1	Protein CBR-APH-1. (330 aa)
	CBG26722	Protein CBG26722. (1274 aa)
	CBG26021	Protein CBG26021. (398 aa)
	CBG27628	Protein CBG27628. (685 aa)
	CBG26830	Protein CBG26830. (121 aa)
	spe-4	Protein CBR-SPE-4. (483 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00724	lag-1	A8WN76	A8X027	Protein CBG00724.	Protein CBR-LAG-1.	0.564
CBG03682	lag-1	A8WVL0	A8X027	Protein CBG03682.	Protein CBR-LAG-1.	0.564
CBG05362	CBG06829	A8WZP3	A8X360	Protein CBG05362.	Protein CBG06829.	0.938
CBG05362	aph-1	A8WZP3	B0K098	Protein CBG05362.	Protein CBR-APH-1.	0.907
CBG05362	aph-2	A8WZP3	A8XZV7	Protein CBG05362.	Protein CBR-APH-2.	0.912
CBG05362	hop-1	A8WZP3	A8XEJ8	Protein CBG05362.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.911
CBG05362	lag-1	A8WZP3	A8X027	Protein CBG05362.	Protein CBR-LAG-1.	0.928
CBG05362	lin-12.2	A8WZP3	A8X358	Protein CBG05362.	Protein CBR-LIN-12.	0.921
CBG05362	pen-2	A8WZP3	A8XHA1	Protein CBG05362.	Protein CBR-PEN-2.	0.907
CBG05362	sel-12	A8WZP3	A8X5S7	Protein CBG05362.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.911
CBG05362	spe-4	A8WZP3	G2J6Q7	Protein CBG05362.	Protein CBR-SPE-4.	0.911
CBG06829	CBG05362	A8X360	A8WZP3	Protein CBG06829.	Protein CBG05362.	0.938
CBG06829	aph-1	A8X360	B0K098	Protein CBG06829.	Protein CBR-APH-1.	0.926
CBG06829	aph-2	A8X360	A8XZV7	Protein CBG06829.	Protein CBR-APH-2.	0.966
CBG06829	hop-1	A8X360	A8XEJ8	Protein CBG06829.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.968
CBG06829	kpc-1	A8X360	A8XMZ6	Protein CBG06829.	Protein CBR-KPC-1; Belongs to the peptidase S8 family.	0.699
CBG06829	lag-1	A8X360	A8X027	Protein CBG06829.	Protein CBR-LAG-1.	0.999
CBG06829	lin-12.2	A8X360	A8X358	Protein CBG06829.	Protein CBR-LIN-12.	0.901
CBG06829	pen-2	A8X360	A8XHA1	Protein CBG06829.	Protein CBR-PEN-2.	0.954
CBG06829	sel-12	A8X360	A8X5S7	Protein CBG06829.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.971