(46 nodes) Stabilization of membrane potential, and Voltage-gated channel network (Caenorhabditis briggsae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	twk-18	Protein CBR-TWK-18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (461 aa)
	shw-1	Protein CBR-SHW-1; Belongs to the potassium channel family. (775 aa)
	twk-4	Protein CBR-TWK-4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (401 aa)
	sup-10	Protein CBR-SUP-10. (355 aa)
	CBG02091	Protein CBG02091; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (562 aa)
	CBG03693	Protein CBG03693. (679 aa)
	twk-47	Protein CBR-TWK-47. (435 aa)
	CBG04158	Protein CBG04158. (876 aa)
	twk-29	Protein CBR-TWK-29; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (470 aa)
	kcnl-4	Protein CBR-KCNL-4. (484 aa)
	twk-34	Protein CBR-TWK-34; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (564 aa)
	twk-35	Protein CBR-TWK-35; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (557 aa)
	twk-33	Protein CBR-TWK-33; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (619 aa)
	CBG06195	Protein CBG06195; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (576 aa)
	twk-25	Protein CBR-TWK-25; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (715 aa)
	twk-20	Two pore potassium channel protein sup-9. (341 aa)
	irk-2	Protein CBR-IRK-2. (531 aa)
	CBG08684	Protein CBG08684. (909 aa)
	unc-93	Protein CBR-UNC-93. (674 aa)
	twk-48	Protein CBR-TWK-48; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (372 aa)
	irk-3	Protein CBR-IRK-3. (369 aa)
	twk-32	Protein CBR-TWK-32; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (629 aa)
	best-24	Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (576 aa)
	sup-18	Protein CBG12270. (260 aa)
	skpo-3	Protein CBG13113. (1083 aa)
	twk-28	Protein CBR-TWK-28; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (537 aa)
	lgc-53	Protein CBR-LGC-53; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
	Cbr-twk-17	Protein CBR-TWK-17. (148 aa)
	twk-44	Protein CBR-TWK-44; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (944 aa)
	CBG17532	Protein CBG17532. (173 aa)
	twk-43	Protein CBR-TWK-43; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (609 aa)
	skpo-2	Protein CBG17768. (735 aa)
	CBG18207	Protein CBG18207. (99 aa)
	kvs-4	Protein CBR-KVS-4; Belongs to the potassium channel family. (497 aa)
	twk-40	Protein CBR-TWK-40; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (393 aa)
	twk-10	Protein CBR-TWK-10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (285 aa)
	sup-9	Two pore potassium channel protein sup-9. (325 aa)
	wht-3	Protein CBR-WHT-3. (606 aa)
	twk-46	Two pore potassium channel protein sup-9. (318 aa)
	twk-1	Protein CBR-TWK-1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (463 aa)
	CBG22159	Protein CBG22159. (91 aa)
	egl-23	Protein CBR-EGL-23; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (673 aa)
	twk-14	Protein CBR-TWK-14; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (438 aa)
	CBG26581	Protein CBG26581. (53 aa)
	Cbr-twk-2	Protein CBR-TWK-2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (983 aa)
	unc-58	Uncoordinated protein 58; Has a role in mobility, possibly in the transport of potassium in muscles; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (593 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG02091	skpo-2	A8WRY8	A8XRR7	Protein CBG02091; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Protein CBG17768.	0.843
CBG02091	skpo-3	A8WRY8	A8XH40	Protein CBG02091; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Protein CBG13113.	0.839
CBG02091	sup-18	A8WRY8	A8XF51	Protein CBG02091; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Protein CBG12270.	0.748
CBG02091	twk-20	A8WRY8	A8X4U9	Protein CBG02091; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Two pore potassium channel protein sup-9.	0.626
CBG02091	twk-4	A8WRY8	A8WPC4	Protein CBG02091; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Protein CBR-TWK-4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.627
CBG03693	sup-9	A8WVL8	A8XVW8	Protein CBG03693.	Two pore potassium channel protein sup-9.	0.499
CBG03693	twk-14	A8WVL8	A8Y3U3	Protein CBG03693.	Protein CBR-TWK-14; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.428
CBG03693	twk-46	A8WVL8	A8XXJ8	Protein CBG03693.	Two pore potassium channel protein sup-9.	0.552
CBG04158	CBG17532	A8WWA7	A8XR66	Protein CBG04158.	Protein CBG17532.	0.658
CBG04158	best-24	A8WWA7	A8XF43	Protein CBG04158.	Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family.	0.632
CBG04158	egl-23	A8WWA7	A8Y2B8	Protein CBG04158.	Protein CBR-EGL-23; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.499
CBG04158	kvs-4	A8WWA7	A8XS70	Protein CBG04158.	Protein CBR-KVS-4; Belongs to the potassium channel family.	0.631
CBG04158	shw-1	A8WWA7	A8WNA6	Protein CBG04158.	Protein CBR-SHW-1; Belongs to the potassium channel family.	0.646
CBG04158	twk-29	A8WWA7	A8WWM8	Protein CBG04158.	Protein CBR-TWK-29; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.579
CBG04158	twk-33	A8WWA7	A8X0F6	Protein CBG04158.	Protein CBR-TWK-33; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.641
CBG04158	twk-35	A8WWA7	A8X056	Protein CBG04158.	Protein CBR-TWK-35; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.641
CBG04158	twk-43	A8WWA7	A8XRB6	Protein CBG04158.	Protein CBR-TWK-43; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.521
CBG04158	twk-46	A8WWA7	A8XXJ8	Protein CBG04158.	Two pore potassium channel protein sup-9.	0.468
CBG04158	twk-48	A8WWA7	A8XA16	Protein CBG04158.	Protein CBR-TWK-48; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.530
CBG06195	skpo-2	A8X0P5	A8XRR7	Protein CBG06195; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.	Protein CBG17768.	0.847