(129 nodes) Mixed, incl. Transport of inorganic cations/anions and amino acids/oligopeptides, and Ion transport by P-type ATPases network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	aat-9	Protein CBR-AAT-4. (544 aa)
	best-7.2	Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (541 aa)
	CBG23873	Protein CBG23873; Belongs to the CDC50/LEM3 family. (361 aa)
	CBG24098	Protein CBG24098. (460 aa)
	atgp-1	Protein CBR-ATGP-1. (613 aa)
	tub-1	Tubby protein homolog 1; Has a role in fat regulation independent of daf-16. Implicated in ciliar sensory function which is required for normal sensory behavior such as chemotaxis. Functions in life span control via the insulin/IGF-1 pathway. Thought to be involved in neuronal trafficking (By similarity). (424 aa)
	CBG01062	Protein CBG01062. (273 aa)
	chat-1	Protein CBR-CHAT-1; Belongs to the CDC50/LEM3 family. (350 aa)
	aat-3	Protein CBR-AAT-3. (492 aa)
	CBG03118	Protein CBG03118. (492 aa)
	col-79	Protein CBR-COL-79. (282 aa)
	tat-4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1235 aa)
	Cbr-tat-4.2	Protein CBR-TAT-4.2. (319 aa)
	CBG02480	Protein CBG02480. (148 aa)
	CBG02443	Protein CBG02443. (310 aa)
	mca-3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1159 aa)
	tbc-3	Protein CBG03461. (527 aa)
	CBG03940	Protein CBG03940. (384 aa)
	CBG04043	Protein CBG04043. (115 aa)
	CBG04045	Protein CBG04045. (159 aa)
	abts-1	Anion exchange protein. (1178 aa)
	CBG04103	Protein CBG04103. (451 aa)
	aat-5	Protein CBR-AAT-5. (537 aa)
	nkb-1	Protein CBR-NKB-1. (319 aa)
	ikb-1	Protein CBR-IKB-1. (605 aa)
	glt-4	Amino acid transporter. (514 aa)
	pept-1	Protein CBR-PEPT-1. (838 aa)
	kcc-2	Protein CBR-KCC-3. (973 aa)
	CBG06177	Protein CBG06177. (284 aa)
	best-7.1	Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (533 aa)
	glt-6	Amino acid transporter. (540 aa)
	kcc-1	Protein CBR-KCC-1. (1109 aa)
	srh-57	Protein CBG06304. (267 aa)
	Cbr-srt-41	Protein CBR-SRT-41. (361 aa)
	CBG06685	Putative selenium-binding protein; Belongs to the selenium-binding protein family. (514 aa)
	nac-2	Protein CBR-NAC-2. (566 aa)
	snf-3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
	CBG07159	Protein CBG07159. (448 aa)
	CBG07084	Protein CBG07084. (959 aa)
	fgt-1	Protein CBR-FGT-1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (537 aa)
	CBG07007	Protein CBG07007. (585 aa)
	CBG06984	Protein CBG06984. (618 aa)
	nac-1	Protein CBR-NAC-1. (581 aa)
	nkb-3	Probable sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Implicated in genomic response to various soil bacteria that affects fitness, lifespan and brood size (By similarity). (326 aa)
	abhd-3.2	Protein CBG08080. (375 aa)
	CBG08105	Protein CBG08105. (210 aa)
	CBG08211	Protein CBG08211. (342 aa)
	ath-1	Protein CBR-ATH-1. (266 aa)
	catp-1	Protein CBR-CATP-1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1130 aa)
	Cbr-ugt-8	Protein CBR-UGT-8. (549 aa)
	CBG09010	Protein CBG09010. (1019 aa)
	CBG09596	Protein CBG09596. (454 aa)
	pqn-68	D-aminoacyl-tRNA deacylase. (150 aa)
	eat-6	Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
	CBG09262	Protein CBG09262. (94 aa)
	nac-3	Protein CBR-NAC-3. (566 aa)
	CBG09837	Protein CBG09837. (420 aa)
	CBG09854	Phospholipase B-like; Putative phospholipase. (582 aa)
	CBG10435	Protein CBG10435. (466 aa)
	CBG10451	Protein CBG10451. (415 aa)
	CBG10452	Protein CBG10452. (428 aa)
	CBG10453	Protein CBG10453. (428 aa)
	CBG10454	Protein CBG10454. (432 aa)
	CBG10455	Protein CBG10455. (252 aa)
	aat-8	Protein CBR-AAT-8. (516 aa)
	snf-1	Protein CBR-SNF-1. (616 aa)
	atgp-2	Protein CBR-ATGP-2. (666 aa)
	CBG11438	Protein CBG11438. (304 aa)
	tat-2	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1526 aa)
	tat-1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1218 aa)
	CBG12426	Protein CBG12426. (492 aa)
	CBG12474	Protein CBG12474. (1438 aa)
	CBG12559	Protein CBG12559. (469 aa)
	nhx-2	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (668 aa)
	mib-1	Protein CBR-MIB-1. (766 aa)
	ipla-1	Protein CBR-IPLA-1. (750 aa)
	CBG13798	Protein CBG13798. (727 aa)
	CBG13831	Protein CBG13831. (421 aa)
	cnnm-3	Protein CBG14121. (417 aa)
	gpcp-1	Protein CBG14135. (616 aa)
	glt-1	Amino acid transporter. (492 aa)
	CBG14567	Protein CBG14567. (371 aa)
	lpd-3	Protein CBG14931. (3899 aa)
	CBG15341	Protein CBG15341. (937 aa)
	cyp-37b1	Protein CBR-CYP-37B1; Belongs to the cytochrome P450 family. (508 aa)
	CBG16211	Protein CBG16211; Belongs to the CDC50/LEM3 family. (350 aa)
	CBG16566	Protein CBG16566. (513 aa)
	CBG16737	Protein CBG16737. (351 aa)
	catp-5	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1227 aa)
	tat-5	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1072 aa)
	CBG17275	Protein CBG17275. (502 aa)
	abts-2	Protein CBR-ABTS-2. (754 aa)
	oct-2	Protein CBR-OCT-2. (774 aa)
	sulp-7	Protein CBR-SULP-7. (520 aa)
	sca-1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1081 aa)
	tat-3	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1402 aa)
	CBG18327	Protein CBG18327. (713 aa)
	rbg-3	Protein CBR-RBG-3. (431 aa)
	CBG17998	Protein CBG17998. (291 aa)
	CBG18085	Protein CBG18085. (585 aa)
	CBG18125	Protein CBG18125. (169 aa)
	Cbr-nkcc-1	Protein CBR-NKCC-1. (1191 aa)
	pitr-5	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (509 aa)
	pitr-3	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (494 aa)
	aat-2	Protein CBR-AAT-2. (483 aa)
	pitr-4	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (523 aa)
	sulp-8	Protein CBR-SULP-8. (614 aa)
	CBG19625	Protein CBG19625. (585 aa)
	CBG19651	Protein CBG19651; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1166 aa)
	aat-1	Protein CBR-AAT-1. (495 aa)
	mca-1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1259 aa)
	abhd-11.2	Protein CBG20335. (299 aa)
	CBG20828	Protein CBG20828. (288 aa)
	pitr-6	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (486 aa)
	nrfl-1	Protein CBR-TAG-60. (459 aa)
	CBG22222	Protein CBG22222. (475 aa)
	mca-2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1165 aa)
	CBG22797	Protein CBG22797. (293 aa)
	CBG22811	Protein CBG22811. (428 aa)
	sulp-5	Protein CBR-SULP-5. (735 aa)
	aat-6	Protein CBR-AAT-6. (513 aa)
	CBG26757	Protein CBG26757. (186 aa)
	CBG26382	Protein CBG26382. (95 aa)
	CBG26312	Protein CBG26312. (149 aa)
	ugt-3	Protein CBG27010. (531 aa)
	CBG26473	Protein CBG26473. (483 aa)
	pad-1	Protein pad-1; Essential for cell patterning during gastrulation. May be involved in protein traffic between late Golgi and early endosomes (By similarity). (2340 aa)
	CBG06228	Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes. (1645 aa)
	CBG00135	Probable calcium-binding mitochondrial carrier CBG00135; Calcium-dependent mitochondrial solute carrier. Belongs to the mitochondrial carrier (TC 2.A.29) family. (532 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00135	CBG09837	Q628Z2	A8X9R9	Probable calcium-binding mitochondrial carrier CBG00135; Calcium-dependent mitochondrial solute carrier. Belongs to the mitochondrial carrier (TC 2.A.29) family.	Protein CBG09837.	0.866
CBG02443	CBG04103	A8WUB3	A8WW80	Protein CBG02443.	Protein CBG04103.	0.866
CBG02443	CBG12426	A8WUB3	A8XFE8	Protein CBG02443.	Protein CBG12426.	0.694
CBG02443	CBG12559	A8WUB3	A8XG15	Protein CBG02443.	Protein CBG12559.	0.859
CBG03118	pitr-3	A8WSR2	A8XV28	Protein CBG03118.	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.	0.627
CBG03118	pitr-4	A8WSR2	A8XVE0	Protein CBG03118.	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.	0.644
CBG03118	pitr-5	A8WSR2	A8XUS4	Protein CBG03118.	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.	0.644
CBG03118	pitr-6	A8WSR2	A8XZ26	Protein CBG03118.	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.	0.644
CBG03940	ath-1	A8WVT4	A8X629	Protein CBG03940.	Protein CBR-ATH-1.	0.410
CBG04043	CBG04045	A8WW26	A8WW28	Protein CBG04043.	Protein CBG04045.	0.464
CBG04043	CBG26757	A8WW26	B6IED2	Protein CBG04043.	Protein CBG26757.	0.439
CBG04043	pad-1	A8WW26	Q5WNI9	Protein CBG04043.	Protein pad-1; Essential for cell patterning during gastrulation. May be involved in protein traffic between late Golgi and early endosomes (By similarity).	0.494
CBG04043	tat-5	A8WW26	A8XQ33	Protein CBG04043.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.439
CBG04045	CBG04043	A8WW28	A8WW26	Protein CBG04045.	Protein CBG04043.	0.464
CBG04045	CBG26757	A8WW28	B6IED2	Protein CBG04045.	Protein CBG26757.	0.439
CBG04045	pad-1	A8WW28	Q5WNI9	Protein CBG04045.	Protein pad-1; Essential for cell patterning during gastrulation. May be involved in protein traffic between late Golgi and early endosomes (By similarity).	0.494
CBG04045	tat-5	A8WW28	A8XQ33	Protein CBG04045.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.439
CBG04103	CBG02443	A8WW80	A8WUB3	Protein CBG04103.	Protein CBG02443.	0.866
CBG06228	CBG26757	Q61SD1	B6IED2	Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes.	Protein CBG26757.	0.470
CBG06228	ipla-1	Q61SD1	A8XHR3	Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes.	Protein CBR-IPLA-1.	0.656