(33 nodes) Mixed, incl. O-glycosylation of TSR domain-containing proteins, and Pyridine-containing compound metabolic process network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG24243	Protein CBG24243. (790 aa)
	Cbr-hlh-12	Protein CBR-HLH-12. (193 aa)
	pad-2	Protein CBR-PAD-2. (425 aa)
	gon-1	Protein CBR-GON-1. (2153 aa)
	CBG03468	Protein CBG03468. (158 aa)
	pdxk-1	Protein CBG03945. (323 aa)
	CBG06820	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (307 aa)
	CBG06873	Protein CBG06873. (935 aa)
	dnsn-1	Protein CBG07061. (606 aa)
	CBG07429	Protein CBG07429. (494 aa)
	CBG07973	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (235 aa)
	CBG08740	Protein CBG08740. (127 aa)
	CBG09575	Hexosyltransferase. (496 aa)
	CBG09318	Protein CBG09318. (450 aa)
	CBG10970	Protein CBG10970. (1495 aa)
	hlh-16	Protein CBR-HLH-16. (113 aa)
	pqn-26	Protein CBR-PQN-26. (631 aa)
	madd-4	Protein CBR-MADD-4. (1042 aa)
	spon-1	Protein CBR-SPON-1. (854 aa)
	CBG14267	Protein CBG14267. (219 aa)
	adt-3	Protein CBG14312. (1072 aa)
	CBG14840	Protein CBG14840. (242 aa)
	set-29	Protein CBR-SET-29. (421 aa)
	CBG16488	Protein CBG16488. (246 aa)
	CBG17547	Protein CBG17547. (828 aa)
	hlh-12.1	Protein CBG18498. (159 aa)
	CBG18500	Protein CBG18500. (61 aa)
	wht-6	Protein CBR-WHT-6. (613 aa)
	CBG20501	Protein CBG20501. (1556 aa)
	CBG22017	Protein CBG22017. (565 aa)
	CBG22163	Protein CBG22163. (666 aa)
	col-101	Protein CBR-COL-101. (312 aa)
	CBG23464	Protein CBG23464. (800 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG06820	CBG07973	A8X354	A8X5H6	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	0.898
CBG06820	CBG14267	A8X354	A8XJM7	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.	Protein CBG14267.	0.414
CBG06820	CBG16488	A8X354	A8XPB7	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.	Protein CBG16488.	0.414
CBG06873	CBG09318	A8X395	A8X9D7	Protein CBG06873.	Protein CBG09318.	0.546
CBG06873	pad-2	A8X395	A8WL26	Protein CBG06873.	Protein CBR-PAD-2.	0.485
CBG06873	spon-1	A8X395	A8XH06	Protein CBG06873.	Protein CBR-SPON-1.	0.423
CBG07973	CBG06820	A8X5H6	A8X354	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.	0.898
CBG07973	CBG14267	A8X5H6	A8XJM7	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	Protein CBG14267.	0.824
CBG07973	CBG14840	A8X5H6	A8XKT7	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	Protein CBG14840.	0.898
CBG07973	CBG16488	A8X5H6	A8XPB7	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	Protein CBG16488.	0.774
CBG07973	pdxk-1	A8X5H6	A8WVT6	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	Protein CBG03945.	0.575
CBG08740	CBG09575	A8X7A0	A8X8S2	Protein CBG08740.	Hexosyltransferase.	0.737
CBG08740	CBG20501	A8X7A0	A8XXY3	Protein CBG08740.	Protein CBG20501.	0.644
CBG08740	dnsn-1	A8X7A0	A8X3T0	Protein CBG08740.	Protein CBG07061.	0.738
CBG08740	pad-2	A8X7A0	A8WL26	Protein CBG08740.	Protein CBR-PAD-2.	0.643
CBG08740	pdxk-1	A8X7A0	A8WVT6	Protein CBG08740.	Protein CBG03945.	0.685
CBG08740	set-29	A8X7A0	A8XLD8	Protein CBG08740.	Protein CBR-SET-29.	0.740
CBG09318	CBG06873	A8X9D7	A8X395	Protein CBG09318.	Protein CBG06873.	0.546
CBG09318	CBG17547	A8X9D7	A8XR79	Protein CBG09318.	Protein CBG17547.	0.407
CBG09318	adt-3	A8X9D7	A8XJR0	Protein CBG09318.	Protein CBG14312.	0.407