STRINGSTRING
Cbr-mel-11 Cbr-mel-11 ltd-1 ltd-1 CBG01632 CBG01632 ssr-2 ssr-2 CBG03290 CBG03290 spv-1 spv-1 rga-1 rga-1 Cbr-max-2 Cbr-max-2 max-2 max-2 CBG02683 CBG02683 drn-1 drn-1 pxf-1 pxf-1 hum-7 hum-7 let-502 let-502 CBG03971 CBG03971 mek-2 mek-2 git-1 git-1 let-60 let-60 rap-3 rap-3 lip-1 lip-1 CBG06442 CBG06442 CBG07097 CBG07097 pix-1 pix-1 CBG08006 CBG08006 src-2 src-2 CBG09025 CBG09025 chw-1 chw-1 crp-1 crp-1 epac-1 epac-1 rap-2 rap-2 CBG12069 CBG12069 CBG12078 CBG12078 CBG12199 CBG12199 CBG12197 CBG12197 CBG12536 CBG12536 CBG12765 CBG12765 cdc-42 cdc-42 rga-2 rga-2 rho-1 rho-1 CBG13699 CBG13699 gap-1 gap-1 rgl-1 rgl-1 nck-1 nck-1 rhi-1 rhi-1 pak-1 pak-1 ral-1 ral-1 ksr-2 ksr-2 pkc-2 pkc-2 CBG16121 CBG16121 gap-2 gap-2 pkn-1 pkn-1 mig-2 mig-2 Cbr-tag-325 Cbr-tag-325 ras-2 ras-2 pes-7 pes-7 mrck-1 mrck-1 rgef-1 rgef-1 soc-2 soc-2 ras-1 ras-1 CBG21094 CBG21094 mpk-1 mpk-1 rap-1 rap-1 CBG22069 CBG22069 gap-3 gap-3 rga-5 rga-5 ksr-1 ksr-1 pak-2 pak-2 CBG25550 CBG25550 CBG26388 CBG26388 CBG26591 CBG26591 CBG27691 CBG27691 CBG14590 CBG14590 lin-45 lin-45
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cbr-mel-11Protein CBG24954. (336 aa)
ltd-1Protein CBR-LTD-1. (723 aa)
CBG01632Protein CBG01632. (346 aa)
ssr-2Protein CBR-SSR-2. (323 aa)
CBG03290Protein CBG03290. (169 aa)
spv-1Protein CBR-TAG-341. (855 aa)
rga-1Protein CBR-RGA-1. (439 aa)
Cbr-max-2Protein CBR-MAX-2; Belongs to the protein kinase superfamily. (422 aa)
max-2Protein CBG02801. (317 aa)
CBG02683Protein CBG02683. (257 aa)
drn-1Protein CBR-DRN-1. (310 aa)
pxf-1Protein CBR-PXF-1. (1469 aa)
hum-7Protein CBR-HUM-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1886 aa)
let-502Rho-associated protein kinase let-502; Negatively regulates mel-11 to relieve the inhibition of mlc- 4, allowing contraction of the circumferentially oriented microfilaments in epidermal cells and thereby regulating myosin II contractility during spermathecal contraction, cleavage furrow contraction in early embryos, and embryonic elongation and morphogenesis. Required for P-cell migration. May also play a role in oocyte cellularization (By similarity). (1194 aa)
CBG03971Protein CBG03971. (290 aa)
mek-2Protein CBR-MEK-2; Belongs to the protein kinase superfamily. (387 aa)
git-1Protein CBR-GIT-1. (659 aa)
let-60Protein CBR-LET-60. (184 aa)
rap-3Protein CBR-RAP-3. (99 aa)
lip-1Protein CBR-LIP-1. (376 aa)
CBG06442Protein CBG06442. (210 aa)
CBG07097Protein CBG07097. (736 aa)
pix-1Protein CBR-PIX-1. (808 aa)
CBG08006Protein CBG08006. (468 aa)
src-2Tyrosine-protein kinase. (512 aa)
CBG09025Protein CBG09025. (934 aa)
chw-1Protein CBR-CHW-1. (207 aa)
crp-1Protein CBR-CRP-1. (187 aa)
epac-1Protein CBR-EPAC-1. (1101 aa)
rap-2Protein CBR-RAP-2. (181 aa)
CBG12069Protein CBG12069. (1567 aa)
CBG12078Protein CBG12078. (812 aa)
CBG12199Protein CBG12199. (193 aa)
CBG12197Protein CBG12197. (158 aa)
CBG12536Protein CBG12536. (287 aa)
CBG12765Protein CBG12765. (713 aa)
cdc-42Protein CBR-CDC-42. (191 aa)
rga-2Protein CBR-RGA-2. (914 aa)
rho-1Protein CBR-RHO-1. (192 aa)
CBG13699Protein CBG13699. (277 aa)
gap-1Protein CBR-GAP-1. (1265 aa)
rgl-1Protein CBR-RGL-1. (865 aa)
nck-1Protein CBR-NCK-1. (393 aa)
rhi-1Protein CBR-RHI-1. (191 aa)
pak-1Non-specific serine/threonine protein kinase. (626 aa)
ral-1Protein CBR-RAL-1. (213 aa)
ksr-2Protein CBR-KSR-2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (589 aa)
pkc-2Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (941 aa)
CBG16121Protein CBG16121. (210 aa)
gap-2Protein CBR-GAP-2. (824 aa)
pkn-1Protein CBR-PKN-1. (1149 aa)
mig-2Protein CBR-MIG-2. (195 aa)
Cbr-tag-325Protein CBR-TAG-325. (853 aa)
ras-2Protein CBR-RAS-2. (211 aa)
pes-7Protein CBR-PES-7. (1406 aa)
mrck-1Protein CBR-MRCK-1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1586 aa)
rgef-1Protein CBR-RGEF-1. (676 aa)
soc-2Leucine-rich repeat protein soc-2; Acts as a Ras effector and participates in MAPK pathway activation. Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulates Raf activity at specialized signaling complexes upon Ras activation. Required for vulval development. Involved in fluid homeostasis. Plays a role in nicotinic acetylcholine receptor (nAChR)- mediated sensitivity to nicotine; Belongs to the SHOC2 family. (559 aa)
ras-1Protein CBR-RAS-1. (211 aa)
CBG21094Protein CBG21094. (344 aa)
mpk-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
rap-1Protein CBR-RAP-1. (188 aa)
CBG22069Protein CBG22069. (338 aa)
gap-3Protein CBG22075. (960 aa)
rga-5Protein CBR-RGA-5. (1327 aa)
ksr-1Protein CBR-KSR-1. (812 aa)
pak-2Non-specific serine/threonine protein kinase. (515 aa)
CBG25550Protein CBG25550. (147 aa)
CBG26388Protein CBG26388. (223 aa)
CBG26591Protein CBG26591. (136 aa)
CBG27691Protein CBG27691. (404 aa)
CBG14590Protein CBG14590. (434 aa)
lin-45Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1. (811 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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