STRINGSTRING
Cbr-mel-11 Cbr-mel-11 rga-1 rga-1 Cbr-max-2 Cbr-max-2 max-2 max-2 hum-7 hum-7 let-502 let-502 git-1 git-1 pix-1 pix-1 chw-1 chw-1 crp-1 crp-1 CBG12069 CBG12069 cdc-42 cdc-42 rga-2 rga-2 rho-1 rho-1 CBG13699 CBG13699 nck-1 nck-1 pak-1 pak-1 pkn-1 pkn-1 mig-2 mig-2 Cbr-tag-325 Cbr-tag-325 mrck-1 mrck-1 pak-2 pak-2 CBG26591 CBG26591 CBG14590 CBG14590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cbr-mel-11Protein CBG24954. (336 aa)
rga-1Protein CBR-RGA-1. (439 aa)
Cbr-max-2Protein CBR-MAX-2; Belongs to the protein kinase superfamily. (422 aa)
max-2Protein CBG02801. (317 aa)
hum-7Protein CBR-HUM-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1886 aa)
let-502Rho-associated protein kinase let-502; Negatively regulates mel-11 to relieve the inhibition of mlc- 4, allowing contraction of the circumferentially oriented microfilaments in epidermal cells and thereby regulating myosin II contractility during spermathecal contraction, cleavage furrow contraction in early embryos, and embryonic elongation and morphogenesis. Required for P-cell migration. May also play a role in oocyte cellularization (By similarity). (1194 aa)
git-1Protein CBR-GIT-1. (659 aa)
pix-1Protein CBR-PIX-1. (808 aa)
chw-1Protein CBR-CHW-1. (207 aa)
crp-1Protein CBR-CRP-1. (187 aa)
CBG12069Protein CBG12069. (1567 aa)
cdc-42Protein CBR-CDC-42. (191 aa)
rga-2Protein CBR-RGA-2. (914 aa)
rho-1Protein CBR-RHO-1. (192 aa)
CBG13699Protein CBG13699. (277 aa)
nck-1Protein CBR-NCK-1. (393 aa)
pak-1Non-specific serine/threonine protein kinase. (626 aa)
pkn-1Protein CBR-PKN-1. (1149 aa)
mig-2Protein CBR-MIG-2. (195 aa)
Cbr-tag-325Protein CBR-TAG-325. (853 aa)
mrck-1Protein CBR-MRCK-1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1586 aa)
pak-2Non-specific serine/threonine protein kinase. (515 aa)
CBG26591Protein CBG26591. (136 aa)
CBG14590Protein CBG14590. (434 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.