(11 nodes) RHOU GTPase cycle, and Rho (Ras homology) subfamily of Ras-like small GTPases network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cbr-max-2	Protein CBR-MAX-2; Belongs to the protein kinase superfamily. (422 aa)
	max-2	Protein CBG02801. (317 aa)
	git-1	Protein CBR-GIT-1. (659 aa)
	pix-1	Protein CBR-PIX-1. (808 aa)
	crp-1	Protein CBR-CRP-1. (187 aa)
	CBG12069	Protein CBG12069. (1567 aa)
	cdc-42	Protein CBR-CDC-42. (191 aa)
	nck-1	Protein CBR-NCK-1. (393 aa)
	pak-1	Non-specific serine/threonine protein kinase. (626 aa)
	mig-2	Protein CBR-MIG-2. (195 aa)
	pak-2	Non-specific serine/threonine protein kinase. (515 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG12069	Cbr-max-2	A8XEH4	A8WTH2	Protein CBG12069.	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	0.606
CBG12069	cdc-42	A8XEH4	A8XGW3	Protein CBG12069.	Protein CBR-CDC-42.	0.948
CBG12069	crp-1	A8XEH4	A8X8P6	Protein CBG12069.	Protein CBR-CRP-1.	0.948
CBG12069	git-1	A8XEH4	A8WXS3	Protein CBG12069.	Protein CBR-GIT-1.	0.419
CBG12069	max-2	A8XEH4	A8WTH3	Protein CBG12069.	Protein CBG02801.	0.606
CBG12069	mig-2	A8XEH4	A8XQS8	Protein CBG12069.	Protein CBR-MIG-2.	0.948
CBG12069	nck-1	A8XEH4	A8XJT7	Protein CBG12069.	Protein CBR-NCK-1.	0.443
CBG12069	pak-1	A8XEH4	A8XKR6	Protein CBG12069.	Non-specific serine/threonine protein kinase.	0.606
CBG12069	pak-2	A8XEH4	A8Y4R7	Protein CBG12069.	Non-specific serine/threonine protein kinase.	0.606
Cbr-max-2	CBG12069	A8WTH2	A8XEH4	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBG12069.	0.606
Cbr-max-2	cdc-42	A8WTH2	A8XGW3	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBR-CDC-42.	0.988
Cbr-max-2	crp-1	A8WTH2	A8X8P6	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBR-CRP-1.	0.959
Cbr-max-2	git-1	A8WTH2	A8WXS3	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBR-GIT-1.	0.854
Cbr-max-2	mig-2	A8WTH2	A8XQS8	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBR-MIG-2.	0.975
Cbr-max-2	nck-1	A8WTH2	A8XJT7	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBR-NCK-1.	0.978
Cbr-max-2	pak-1	A8WTH2	A8XKR6	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.663
Cbr-max-2	pak-2	A8WTH2	A8Y4R7	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.944
Cbr-max-2	pix-1	A8WTH2	A8X4W5	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	Protein CBR-PIX-1.	0.912
cdc-42	CBG12069	A8XGW3	A8XEH4	Protein CBR-CDC-42.	Protein CBG12069.	0.948
cdc-42	Cbr-max-2	A8XGW3	A8WTH2	Protein CBR-CDC-42.	Protein CBR-MAX-2; Belongs to the protein kinase superfamily.	0.988