STRINGSTRING
pcrg-1 pcrg-1 CBG23593 CBG23593 nud-2 nud-2 arx-4 arx-4 nud-1 nud-1 CBG24442 CBG24442 CBG24443 CBG24443 CBG24444 CBG24444 CBG24445 CBG24445 CBG00040 CBG00040 dylt-2 dylt-2 dylt-3 dylt-3 dli-1 dli-1 gex-2 gex-2 CBG01593 CBG01593 CBG01565 CBG01565 wsp-1 wsp-1 CBG02031 CBG02031 CBG02160 CBG02160 CBG02161 CBG02161 CBG02162 CBG02162 CBG02163 CBG02163 CBG02167 CBG02167 CBG02169 CBG02169 mgl-2 mgl-2 dyrb-1 dyrb-1 arp-1 arp-1 CBG03137 CBG03137 ebp-2 ebp-2 cap-2 cap-2 gex-3 gex-3 tba-5 tba-5 dnc-6 dnc-6 arx-7 arx-7 dnc-5 dnc-5 tba-1 tba-1 pfn-1 pfn-1 CBG04771 CBG04771 dyci-1 dyci-1 bicd-1 bicd-1 dlc-5 dlc-5 ebp-1 ebp-1 dlc-2 dlc-2 dnc-1 dnc-1 cap-1 cap-1 daam-1 daam-1 unc-60 unc-60 cpn-2 cpn-2 tba-2 tba-2 pfn-3 pfn-3 chil-10 chil-10 CBG08925 CBG08925 dnc-2 dnc-2 abi-1 abi-1 dhc-3 dhc-3 ben-1 ben-1 fozi-1 fozi-1 clip-1 clip-1 CBG10797 CBG10797 fhod-1 fhod-1 xbx-1 xbx-1 che-3 che-3 CBG11861 CBG11861 CBG11865 CBG11865 dhc-1 dhc-1 hum-1 hum-1 CBG12392 CBG12392 tba-6 tba-6 CBG12766 CBG12766 CBG13091 CBG13091 tba-7 tba-7 dlc-3 dlc-3 CBG13967 CBG13967 plst-1 plst-1 tba-9 tba-9 unc-78 unc-78 CBG14570 CBG14570 CBG14672 CBG14672 CBG14863 CBG14863 exc-6 exc-6 frl-1 frl-1 CBG15718 CBG15718 arx-5 arx-5 CBG15748 CBG15748 CBG16073 CBG16073 toca-1 toca-1 twf-2 twf-2 dyla-1 dyla-1 cas-1 cas-1 tbb-4 tbb-4 tba-8 tba-8 CBG16645 CBG16645 cyk-1 cyk-1 wip-1 wip-1 viro-2 viro-2 efhc-1 efhc-1 dnc-4 dnc-4 arp-11 arp-11 act-5 act-5 dhc-4 dhc-4 CBG18260 CBG18260 dbn-1 dbn-1 toca-2 toca-2 tbb-1 tbb-1 CBG18378 CBG18378 arx-6 arx-6 zyg-8 zyg-8 arx-3 arx-3 bcmo-2 bcmo-2 wve-1 wve-1 CBG19199 CBG19199 CBG19203 CBG19203 gsnl-1 gsnl-1 dlc-1 dlc-1 CBG19815 CBG19815 egal-1 egal-1 mgl-3 mgl-3 tbb-2 tbb-2 lis-1 lis-1 sumv-1 sumv-1 CBG21280 CBG21280 dlc-6 dlc-6 dnc-3 dnc-3 CBG21459 CBG21459 pqn-75 pqn-75 dylt-1 dylt-1 CBG22052 CBG22052 CBG22322 CBG22322 aipl-1 aipl-1 act-2 act-2 act-4 act-4 inft-2 inft-2 Cbr-fozi-1 Cbr-fozi-1 CBG26242 CBG26242 CBG13090 CBG13090 CBG22319 CBG22319 CBG24447 CBG24447 CBG29119 CBG29119 mec-7 mec-7 CBG09753 CBG09753 arx-2 arx-2 arx-1 arx-1 evl-20.1 evl-20.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pcrg-1Protein CBG23554. (262 aa)
CBG23593Protein CBG23593. (439 aa)
nud-2Protein CBR-NUD-2. (281 aa)
arx-4Protein CBR-ARX-4. (539 aa)
nud-1Protein CBR-NUD-1. (311 aa)
CBG24442Protein CBG24442; Belongs to the actin family. (173 aa)
CBG24443Protein CBG24443. (93 aa)
CBG24444Protein CBG24444. (376 aa)
CBG24445Protein CBG24445. (368 aa)
CBG00040Protein CBG00040. (1622 aa)
dylt-2Protein CBR-DYLT-2. (120 aa)
dylt-3Protein CBR-DYLT-3. (73 aa)
dli-1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (441 aa)
gex-2Protein CBR-GEX-2. (1278 aa)
CBG01593Protein CBG01593; Belongs to the G-protein coupled receptor 3 family. (1395 aa)
CBG01565Protein CBG01565. (188 aa)
wsp-1Protein CBR-WSP-1. (785 aa)
CBG02031Protein CBG02031. (692 aa)
CBG02160Protein CBG02160. (395 aa)
CBG02161Protein CBG02161. (372 aa)
CBG02162Protein CBG02162. (372 aa)
CBG02163Protein CBG02163. (93 aa)
CBG02167Protein CBG02167. (372 aa)
CBG02169Protein CBG02169; Belongs to the actin family. (353 aa)
mgl-2Protein CBR-MGL-2. (1083 aa)
dyrb-1Dynein light chain roadblock. (95 aa)
arp-1Protein CBG03145; Belongs to the actin family. (374 aa)
CBG03137Protein CBG03137. (242 aa)
ebp-2Protein CBR-EBP-2. (306 aa)
cap-2F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (271 aa)
gex-3Protein CBR-GEX-3. (1140 aa)
tba-5Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
dnc-6Dynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily. (174 aa)
arx-7Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (152 aa)
dnc-5Protein CBR-DNC-5. (186 aa)
tba-1Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
pfn-1Profilin; Belongs to the profilin family. (132 aa)
CBG04771Protein CBG04771. (1325 aa)
dyci-1Protein CBR-DYCI-1. (663 aa)
bicd-1Protein CBR-BICD-1. (834 aa)
dlc-5Protein CBR-DLC-5. (186 aa)
ebp-1Protein CBR-EBP-1. (303 aa)
dlc-2Dynein light chain. (90 aa)
dnc-1Protein CBR-DNC-1. (1325 aa)
cap-1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa)
daam-1Protein CBR-DAAM-1. (862 aa)
unc-60Protein CBR-UNC-60; Belongs to the actin-binding proteins ADF family. (293 aa)
cpn-2Transgelin; Belongs to the calponin family. (203 aa)
tba-2Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
pfn-3Profilin; Belongs to the profilin family. (114 aa)
chil-10Protein CBG08083; Belongs to the glycosyl hydrolase 18 family. (338 aa)
CBG08925Protein CBG08925; Belongs to the actin family. (389 aa)
dnc-2Protein CBR-DNC-2. (331 aa)
abi-1Protein CBR-ABI-1. (487 aa)
dhc-3Protein CBR-DHC-3. (3304 aa)
ben-1Protein CBR-BEN-1; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (271 aa)
fozi-1Protein CBR-FOZI-1. (688 aa)
clip-1Protein CBG10142. (961 aa)
CBG10797Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (215 aa)
fhod-1Protein CBR-FHOD-1. (1059 aa)
xbx-1Protein CBR-XBX-1. (370 aa)
che-3Protein CBR-CHE-3. (4802 aa)
CBG11861Protein CBG11861. (291 aa)
CBG11865Protein CBG11865. (350 aa)
dhc-1Protein CBR-DHC-1. (4569 aa)
hum-1Protein CBR-HUM-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1131 aa)
CBG12392Protein CBG12392. (595 aa)
tba-6Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (457 aa)
CBG12766Protein CBG12766. (344 aa)
CBG13091Protein CBG13091. (304 aa)
tba-7Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
dlc-3Dynein light chain. (136 aa)
CBG13967Protein CBG13967. (367 aa)
plst-1Protein CBR-PLST-1. (623 aa)
tba-9Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
unc-78Protein CBR-UNC-78. (611 aa)
CBG14570Protein CBG14570. (118 aa)
CBG14672Profilin; Belongs to the profilin family. (131 aa)
CBG14863Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
exc-6Protein CBR-INFT-1. (901 aa)
frl-1Protein CBR-FRL-1. (1175 aa)
CBG15718Protein CBG15718; Belongs to the actin-binding proteins ADF family. GMF subfamily. (138 aa)
arx-5Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
CBG15748Protein CBG15748. (227 aa)
CBG16073Protein CBG16073. (502 aa)
toca-1Protein CBR-TOCA-1. (588 aa)
twf-2Protein CBG16364. (376 aa)
dyla-1Protein CBR-DYLA-1. (271 aa)
cas-1Adenylyl cyclase-associated protein; Belongs to the CAP family. (1230 aa)
tbb-4Protein CBR-TBB-4; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (330 aa)
tba-8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (468 aa)
CBG16645Protein CBG16645. (119 aa)
cyk-1Protein CBR-CYK-1. (1477 aa)
wip-1Protein CBR-WIP-1. (313 aa)
viro-2Protein CBG16600. (552 aa)
efhc-1Protein CBG17221. (461 aa)
dnc-4Protein CBG17741. (412 aa)
arp-11Protein CBR-ARP-11; Belongs to the actin family. (453 aa)
act-5Protein CBR-ACT-5. (375 aa)
dhc-4Protein CBG18257. (2277 aa)
CBG18260Protein CBG18260. (459 aa)
dbn-1Protein CBG18266. (672 aa)
toca-2Protein CBR-TOCA-2. (677 aa)
tbb-1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CBG18378Protein CBG18378. (216 aa)
arx-6Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
zyg-8Protein CBR-ZYG-8. (822 aa)
arx-3Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (382 aa)
bcmo-2Protein CBG18441. (463 aa)
wve-1Protein CBR-WVE-1. (475 aa)
CBG19199Protein CBG19199. (186 aa)
CBG19203Protein CBG19203. (260 aa)
gsnl-1Gelsolin-like protein 1; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). Binds actin but does not nucleate actin polymerization, albeit slows down elongation by blocking the barbed ends. By promoting actin depolymerization, required for the elimination of presynaptic components downstream of the egl-1, ced-4 and ced-3 apoptotic pathway during larval development. (474 aa)
dlc-1Dynein light chain. (89 aa)
CBG19815Protein CBG19815. (290 aa)
egal-1Protein CBR-EGAL-1. (578 aa)
mgl-3Protein CBR-MGL-3. (1046 aa)
tbb-2Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
lis-1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (390 aa)
sumv-1Protein CBG21184. (958 aa)
CBG21280Protein CBG21280. (57 aa)
dlc-6Protein CBR-DLC-6. (127 aa)
dnc-3Protein CBR-DNC-3. (180 aa)
CBG21459Protein CBG21459. (655 aa)
pqn-75Protein CBR-PQN-75. (526 aa)
dylt-1Protein CBR-DYLT-1. (106 aa)
CBG22052Protein CBG22052. (402 aa)
CBG22322Protein CBG22322. (372 aa)
aipl-1Protein CBR-TAG-216. (599 aa)
act-2Protein CBR-ACT-2. (376 aa)
act-4Protein CBG23090. (376 aa)
inft-2Protein CBR-INFT-2. (1159 aa)
Cbr-fozi-1Protein CBG25476. (73 aa)
CBG26242Protein CBG26242. (46 aa)
CBG13090Protein CBG13090. (424 aa)
CBG22319Protein CBG22319. (306 aa)
CBG24447Protein CBG24447. (51 aa)
CBG29119Protein CBG29119. (274 aa)
mec-7Tubulin beta-1 chain; Tubulin is the major constituent of microtubules (Probable). It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (Probable). Plays a role in mechanosensory transduction (touch sensitivity) (By similarity). (441 aa)
CBG09753Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility; Belongs to the CFAP20 family. (203 aa)
arx-2Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). (393 aa)
arx-1Actin-related protein 3; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). (426 aa)
evl-20.1ADP-ribosylation factor-like protein 2; GTP-binding protein that functions in embryogenesis, cytokinesis, germline development and microtubulule cytoskeleton dynamics; Belongs to the small GTPase superfamily. Arf family. (184 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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