(21 nodes) Regulation of TOR signaling, and mTORC1-mediated signalling network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG24891	Protein CBG24891. (259 aa)
	nprl-3	Protein CBG01588. (490 aa)
	raga-1	Protein CBR-RAGA-1. (312 aa)
	npp-18	Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus; Belongs to the WD repeat SEC13 family. (366 aa)
	sesn-1	Protein CBG03915. (557 aa)
	CBG05170	Protein CBG05170. (4154 aa)
	ragc-1	Protein CBR-RAGC-1. (338 aa)
	CBG05980	Protein CBG05980. (613 aa)
	nprl-2	Protein CBG05911. (756 aa)
	CBG09543	Protein CBG09543. (121 aa)
	rheb-1	GTP-binding protein Rheb homolog 1; Binds GTP and exhibits intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rheb family. (206 aa)
	flcn-1	Protein CBG11189. (305 aa)
	lmtr-2	Protein CBG11395. (124 aa)
	let-363	Serine/threonine-protein kinase TOR. (1721 aa)
	immp-1	Protein CBR-IMMP-1. (156 aa)
	CBG13871	Protein CBG13871. (1063 aa)
	CBG14553	Protein CBG14553. (5515 aa)
	CBG21229	Protein CBG21229. (1384 aa)
	daf-15	Protein CBR-DAF-15. (1795 aa)
	lmtr-3	Protein CBG23109. (147 aa)
	CBG18724	Protein CBG18724. (3212 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG05170	CBG09543	A8WZA6	A8X8V0	Protein CBG05170.	Protein CBG09543.	0.932
CBG05170	CBG14553	A8WZA6	A8XK64	Protein CBG05170.	Protein CBG14553.	0.996
CBG05170	CBG18724	A8WZA6	B0K0A5	Protein CBG05170.	Protein CBG18724.	0.975
CBG05170	CBG21229	A8WZA6	A8XZJ6	Protein CBG05170.	Protein CBG21229.	0.924
CBG05170	CBG24891	A8WZA6	A8WLP9	Protein CBG05170.	Protein CBG24891.	0.924
CBG05170	daf-15	A8WZA6	A8Y0U3	Protein CBG05170.	Protein CBR-DAF-15.	0.772
CBG05170	immp-1	A8WZA6	A8XHC0	Protein CBG05170.	Protein CBR-IMMP-1.	0.955
CBG05170	let-363	A8WZA6	A8XFR2	Protein CBG05170.	Serine/threonine-protein kinase TOR.	0.603
CBG05170	lmtr-2	A8WZA6	A8XD44	Protein CBG05170.	Protein CBG11395.	0.665
CBG05170	lmtr-3	A8WZA6	A8Y4P1	Protein CBG05170.	Protein CBG23109.	0.613
CBG05170	npp-18	A8WZA6	A8WVD2	Protein CBG05170.	Nucleoporin SEH1; Probable component of the nuclear pore complex (NPC) which is involved in the trafficking of macromolecules between the cytoplasm and nucleus; Belongs to the WD repeat SEC13 family.	0.999
CBG05170	nprl-2	A8WZA6	A8X1C9	Protein CBG05170.	Protein CBG05911.	0.993
CBG05170	nprl-3	A8WZA6	A8WRB0	Protein CBG05170.	Protein CBG01588.	0.999
CBG05170	raga-1	A8WZA6	A8WT67	Protein CBG05170.	Protein CBR-RAGA-1.	0.972
CBG05170	ragc-1	A8WZA6	A8X0V3	Protein CBG05170.	Protein CBR-RAGC-1.	0.971
CBG05170	rheb-1	A8WZA6	A8XAD0	Protein CBG05170.	GTP-binding protein Rheb homolog 1; Binds GTP and exhibits intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rheb family.	0.713
CBG05170	sesn-1	A8WZA6	A8WVR0	Protein CBG05170.	Protein CBG03915.	0.847
CBG05980	CBG13871	A8X168	A8XJ57	Protein CBG05980.	Protein CBG13871.	0.756
CBG05980	daf-15	A8X168	A8Y0U3	Protein CBG05980.	Protein CBR-DAF-15.	0.656
CBG05980	flcn-1	A8X168	A8XCN5	Protein CBG05980.	Protein CBG11189.	0.619