STRINGSTRING
fzr-1 fzr-1 emb-27 emb-27 cdc-25.4 cdc-25.4 mat-2 mat-2 ify-1 ify-1 cdc-14.2 cdc-14.2 cdc-14.1 cdc-14.1 fzy-1 fzy-1 CBG03913 CBG03913 plk-2 plk-2 skpt-1 skpt-1 CBG05210 CBG05210 cyb-3 cyb-3 znf-207 znf-207 cdc-25.2 cdc-25.2 cya-1 cya-1 CBG07665 CBG07665 gfi-3 gfi-3 cdc-25.3 cdc-25.3 apc-10 apc-10 bub-1 bub-1 cdk-1 cdk-1 mat-1 mat-1 CBG12075 CBG12075 CBG12081 CBG12081 mat-3 mat-3 san-1 san-1 cdc-25.1 cdc-25.1 cki-1 cki-1 such-1 such-1 CBG13581 CBG13581 mdf-2 mdf-2 cdk-2 cdk-2 sep-1 sep-1 CBG15203 CBG15203 cks-1 cks-1 CBG16257 CBG16257 cyb-1 cyb-1 brd-1 brd-1 apc-11 apc-11 CBG18552 CBG18552 mdf-1 mdf-1 chk-2 chk-2 bub-3 bub-3 CBG20697 CBG20697 wee-1.1 wee-1.1 CBG21906 CBG21906 apc-2 apc-2 CBG26435 CBG26435 CBG04144 CBG04144 CBG08049 CBG08049 cki-2 cki-2 wee-1.3 wee-1.3 cyd-1 cyd-1 cdk-4 cdk-4 cye-1 cye-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzr-1Protein CBR-FZR-1. (708 aa)
emb-27Protein CBR-EMB-27. (669 aa)
cdc-25.4Protein CBR-CDC-25.4. (252 aa)
mat-2Protein CBR-MAT-2. (1853 aa)
ify-1Protein CBR-IFY-1. (281 aa)
cdc-14.2Protein CBR-CDC-14. (1044 aa)
cdc-14.1Protein CBG02450. (698 aa)
fzy-1Protein CBR-FZY-1. (521 aa)
CBG03913Protein CBG03913. (215 aa)
plk-2Serine/threonine-protein kinase PLK. (643 aa)
skpt-1Protein CBR-SKPT-1. (418 aa)
CBG05210Protein CBG05210; Belongs to the cyclin family. (290 aa)
cyb-3Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa)
znf-207Protein CBG06068. (332 aa)
cdc-25.2Protein CBG06594. (540 aa)
cya-1Protein CBG06936; Belongs to the cyclin family. (467 aa)
CBG07665Protein CBG07665. (296 aa)
gfi-3Protein CBR-GFI-3. (794 aa)
cdc-25.3Protein CBR-CDC-25.3. (302 aa)
apc-10Protein CBR-APC-10. (144 aa)
bub-1Protein CBR-BUB-1. (971 aa)
cdk-1Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). (326 aa)
mat-1Protein CBR-MAT-1. (746 aa)
CBG12075Protein CBG12075. (611 aa)
CBG12081Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (105 aa)
mat-3Protein CBR-MAT-3. (667 aa)
san-1Protein CBR-SAN-1. (390 aa)
cdc-25.1Protein CBR-CDC-25.1. (615 aa)
cki-1Protein CBR-CKI-1. (187 aa)
such-1Protein CBR-SUCH-1. (769 aa)
CBG13581Protein CBG13581. (651 aa)
mdf-2Protein CBR-MDF-2. (203 aa)
cdk-2Protein CBR-CDK-2; Belongs to the protein kinase superfamily. (340 aa)
sep-1Protein CBR-SEP-1. (1265 aa)
CBG15203Protein CBG15203. (648 aa)
cks-1Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. Has a role in the exit from M phase during early mitotic cell division. More specifically, thought to act by the degrading B-type cyclins that causes breakdown of nuclear envelope and exit mitosis (By similarity). (94 aa)
CBG16257Protein CBG16257. (1420 aa)
cyb-1Protein CBR-CYB-1; Belongs to the cyclin family. (353 aa)
brd-1Protein CBR-BRD-1. (686 aa)
apc-11Protein CBR-APC-11. (134 aa)
CBG18552Protein CBG18552. (515 aa)
mdf-1Protein CBR-MDF-1. (681 aa)
chk-2Protein CBR-CHK-2. (289 aa)
bub-3Protein CBR-BUB-3. (342 aa)
CBG20697Protein CBG20697. (173 aa)
wee-1.1Protein CBG21908; Belongs to the protein kinase superfamily. (419 aa)
CBG21906Protein CBG21906. (185 aa)
apc-2Protein CBR-APC-2; Belongs to the cullin family. (700 aa)
CBG26435Protein CBG26435. (290 aa)
CBG04144Protein CBG04144. (274 aa)
CBG08049Protein CBG08049. (379 aa)
cki-2Protein CBR-CKI-2.1. (256 aa)
wee-1.3Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. (656 aa)
cyd-1Protein CBR-CYD-1; Belongs to the cyclin family. (427 aa)
cdk-4Cyclin-dependent kinase CDK-4/6; Belongs to the protein kinase superfamily. (345 aa)
cye-1G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] (518 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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