STRINGSTRING
cdc-25.4 cdc-25.4 cdc-14.1 cdc-14.1 plk-2 plk-2 CBG05210 CBG05210 cyb-3 cyb-3 cdc-25.2 cdc-25.2 cdk-1 cdk-1 cdc-25.1 cdc-25.1 cyb-1 cyb-1 CBG18552 CBG18552 wee-1.1 wee-1.1 wee-1.3 wee-1.3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdc-25.4Protein CBR-CDC-25.4. (252 aa)
cdc-14.1Protein CBG02450. (698 aa)
plk-2Serine/threonine-protein kinase PLK. (643 aa)
CBG05210Protein CBG05210; Belongs to the cyclin family. (290 aa)
cyb-3Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa)
cdc-25.2Protein CBG06594. (540 aa)
cdk-1Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (By similarity). (326 aa)
cdc-25.1Protein CBR-CDC-25.1. (615 aa)
cyb-1Protein CBR-CYB-1; Belongs to the cyclin family. (353 aa)
CBG18552Protein CBG18552. (515 aa)
wee-1.1Protein CBG21908; Belongs to the protein kinase superfamily. (419 aa)
wee-1.3Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. (656 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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