STRINGSTRING
CBG23781 CBG23781 cand-1 cand-1 CBG23920 CBG23920 rpn-11 rpn-11 rpn-2 rpn-2 pbs-6 pbs-6 CBG00481 CBG00481 Cbr-skr-10 Cbr-skr-10 CBG00496 CBG00496 usp-14 usp-14 CBG00897 CBG00897 CBG01819 CBG01819 csn-6 csn-6 Cbr-csn-3 Cbr-csn-3 pas-5 pas-5 CBG02202 CBG02202 kel-1 kel-1 rpn-9 rpn-9 rpn-12 rpn-12 lin-23 lin-23 CBG02420 CBG02420 CBG02414 CBG02414 CBG02386 CBG02386 lrr-1 lrr-1 pbs-3 pbs-3 skr-1 skr-1 CBG03866 CBG03866 rpn-5 rpn-5 pas-1 pas-1 CBG04772 CBG04772 skr-20 skr-20 skr-19 skr-19 skr-21 skr-21 CBG05318 CBG05318 csn-1 csn-1 CBG06233 CBG06233 ddb-1 ddb-1 skr-16 skr-16 rpn-1 rpn-1 cul-3 cul-3 kel-8 kel-8 rpn-6.2 rpn-6.2 CBG06852 CBG06852 rpt-4 rpt-4 CBG07276 CBG07276 pbs-2 pbs-2 csn-4 csn-4 CBG08559 CBG08559 CBG08524 CBG08524 CBG08898 CBG08898 CBG09111 CBG09111 rpt-3 rpt-3 CBG09040 CBG09040 madf-11 madf-11 CBG09125 CBG09125 CBG09126 CBG09126 pas-2 pas-2 cul-5 cul-5 pas-6 pas-6 rpt-2 rpt-2 CBG09938 CBG09938 ubql-1 ubql-1 pas-3 pas-3 CBG10989 CBG10989 CBG11069 CBG11069 psmd-9 psmd-9 cdt-2 cdt-2 elc-1 elc-1 rpt-6 rpt-6 pbs-4 pbs-4 rpn-8 rpn-8 kel-20 kel-20 CBG11949 CBG11949 wdr-23 wdr-23 pbs-7 pbs-7 pas-4 pas-4 rpn-10 rpn-10 rpt-5 rpt-5 rbx-2 rbx-2 ned-8 ned-8 skr-17 skr-17 CBG12958 CBG12958 cul-4 cul-4 elb-1 elb-1 CBG13260 CBG13260 pas-7 pas-7 ubh-4 ubh-4 pbs-1 pbs-1 CBG14875 CBG14875 CBG14876 CBG14876 CBG15156 CBG15156 CBG15320 CBG15320 CBG15626 CBG15626 CBG15984 CBG15984 CBG16425 CBG16425 CBG16422 CBG16422 fbxl-1 fbxl-1 rpn-6.1 rpn-6.1 rfl-1 rfl-1 CBG16572 CBG16572 CBG16582 CBG16582 CBG16798 CBG16798 CBG17040 CBG17040 CBG17039 CBG17039 CBG17038 CBG17038 CBG17150 CBG17150 vhl-1 vhl-1 CBG17431 CBG17431 CBG17459 CBG17459 CBG17703 CBG17703 cul-2 cul-2 cul-1 cul-1 CBG18387 CBG18387 CBG17991 CBG17991 CBG18037 CBG18037 rpn-3 rpn-3 ula-1 ula-1 ubc-12 ubc-12 ubh-3 ubh-3 ubh-1 ubh-1 CBG18955 CBG18955 rbx-1 rbx-1 CBG19367 CBG19367 CBG19533 CBG19533 CBG19642 CBG19642 CBG19647 CBG19647 rpn-13 rpn-13 CBG19694 CBG19694 pbs-5 pbs-5 skn-1 skn-1 csn-5 csn-5 mec-15 mec-15 csa-1 csa-1 CBG21708 CBG21708 rpn-7 rpn-7 csn-2 csn-2 CBG22161 CBG22161 adpr-1 adpr-1 CBG22545 CBG22545 dcaf-1 dcaf-1 CBG22716 CBG22716 rpt-1 rpt-1 maf-1 maf-1 CBG25600 CBG25600 CBG25234 CBG25234 CBG27741 CBG27741 CBG26557 CBG26557 CBG19761 CBG19761 Cbr-spsb-2 Cbr-spsb-2 CBG20339 CBG20339 png-1 png-1 dcn-1 dcn-1 sel-10 sel-10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG23781Protein CBG23781. (367 aa)
cand-1Protein CBR-CAND-1. (1124 aa)
CBG23920Protein CBG23920; Belongs to the AAA ATPase family. (268 aa)
rpn-11Protein CBR-RPN-11. (312 aa)
rpn-226S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (970 aa)
pbs-6Proteasome subunit beta. (258 aa)
CBG00481Protein CBG00481. (126 aa)
Cbr-skr-10Protein CBR-SKR-10; Belongs to the SKP1 family. (196 aa)
CBG00496Protein CBG00496; Belongs to the SKP1 family. (198 aa)
usp-14Ubiquitin carboxyl-terminal hydrolase. (489 aa)
CBG00897Protein CBG00897. (589 aa)
CBG01819Protein CBG01819. (418 aa)
csn-6Protein CBR-CSN-6. (448 aa)
Cbr-csn-3Protein CBR-CSN-3. (750 aa)
pas-5Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (258 aa)
CBG02202Protein CBG02202; Belongs to the SKP1 family. (174 aa)
kel-1Protein CBR-KEL-1. (615 aa)
rpn-9Protein CBR-RPN-9. (382 aa)
rpn-12Protein CBR-RPN-12. (250 aa)
lin-23Protein CBR-LIN-23. (682 aa)
CBG02420Protein CBG02420. (564 aa)
CBG02414Protein CBG02414; Belongs to the SKP1 family. (284 aa)
CBG02386Protein CBG02386. (738 aa)
lrr-1Protein CBR-LRR-1. (454 aa)
pbs-3Proteasome subunit beta. (204 aa)
skr-1Protein CBR-SKR-1; Belongs to the SKP1 family. (172 aa)
CBG03866Protein CBG03866. (1794 aa)
rpn-5Protein CBR-RPN-5. (491 aa)
pas-1Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa)
CBG04772Protein CBG04772; Belongs to the AAA ATPase family. (426 aa)
skr-20Protein CBR-SKR-20; Belongs to the SKP1 family. (165 aa)
skr-19Protein CBR-SKR-19; Belongs to the SKP1 family. (162 aa)
skr-21Protein CBR-SKR-21; Belongs to the SKP1 family. (166 aa)
CBG05318Protein CBG05318. (577 aa)
csn-1Protein CBR-CSN-1. (580 aa)
CBG06233Protein CBG06233. (399 aa)
ddb-1Protein CBR-DDB-1. (1134 aa)
skr-16Protein CBR-SKR-16; Belongs to the SKP1 family. (181 aa)
rpn-126S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (992 aa)
cul-3Protein CBR-CUL-3; Belongs to the cullin family. (810 aa)
kel-8Protein CBR-KEL-8. (677 aa)
rpn-6.2Probable 26S proteasome regulatory subunit rpn-6.2; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.2 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family. (411 aa)
CBG06852Protein CBG06852. (116 aa)
rpt-4Protein CBR-RPT-4; Belongs to the AAA ATPase family. (398 aa)
CBG07276Protein CBG07276. (968 aa)
pbs-2Proteasome subunit beta. (277 aa)
csn-4Protein CBR-CSN-4. (412 aa)
CBG08559Protein CBG08559. (694 aa)
CBG08524Protein CBG08524. (1917 aa)
CBG08898Protein CBG08898; Belongs to the SKP1 family. (161 aa)
CBG09111Protein CBG09111. (197 aa)
rpt-3Protein CBR-RPT-3; Belongs to the AAA ATPase family. (417 aa)
CBG09040Protein CBG09040; Belongs to the SKP1 family. (186 aa)
madf-11Protein CBR-MADF-11. (531 aa)
CBG09125Protein CBG09125; Belongs to the SKP1 family. (197 aa)
CBG09126Protein CBG09126; Belongs to the SKP1 family. (203 aa)
pas-2Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (231 aa)
cul-5Protein CBR-CUL-5; Belongs to the cullin family. (766 aa)
pas-6Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (255 aa)
rpt-2Protein CBR-RPT-2; Belongs to the AAA ATPase family. (443 aa)
CBG09938Protein CBG09938. (296 aa)
ubql-1Protein CBG10788. (525 aa)
pas-3Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
CBG10989Protein CBG10989; Belongs to the SKP1 family. (208 aa)
CBG11069Protein CBG11069; Belongs to the AAA ATPase family. (438 aa)
psmd-9Protein CBG11181. (196 aa)
cdt-2Protein CBR-CDT-2. (699 aa)
elc-1Protein CBR-ELC-1; Belongs to the SKP1 family. (123 aa)
rpt-6Protein CBR-RPT-6; Belongs to the AAA ATPase family. (417 aa)
pbs-4Proteasome subunit beta. (196 aa)
rpn-8Protein CBR-RPN-8. (382 aa)
kel-20Protein CBG12093. (599 aa)
CBG11949Protein CBG11949; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
wdr-23DDB1- and CUL4-associated factor 11 homolog; Involved in regulation of lifespan. Required for dopaminergic CEP neuron degeneration in response to Mn(2+). (554 aa)
pbs-7Proteasome subunit beta; Belongs to the peptidase T1B family. (251 aa)
pas-4Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (253 aa)
rpn-10Protein CBR-RPN-10. (347 aa)
rpt-5Protein CBR-RPT-5; Belongs to the AAA ATPase family. (430 aa)
rbx-2Protein CBR-RBX-2. (115 aa)
ned-8Protein CBR-NED-8. (76 aa)
skr-17Protein CBR-SKR-17; Belongs to the SKP1 family. (177 aa)
CBG12958Protein CBG12958; Belongs to the SKP1 family. (161 aa)
cul-4Protein CBR-CUL-4; Belongs to the cullin family. (867 aa)
elb-1Protein CBR-ELB-1. (117 aa)
CBG13260Protein CBG13260. (251 aa)
pas-7Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
ubh-4Ubiquitin carboxyl-terminal hydrolase. (326 aa)
pbs-1Proteasome subunit beta. (239 aa)
CBG14875Protein CBG14875; Belongs to the SKP1 family. (154 aa)
CBG14876Protein CBG14876; Belongs to the SKP1 family. (149 aa)
CBG15156Protein CBG15156; Belongs to the SKP1 family. (335 aa)
CBG15320Protein CBG15320. (429 aa)
CBG15626Protein CBG15626; Belongs to the SKP1 family. (208 aa)
CBG15984Protein CBG15984. (160 aa)
CBG16425Protein CBG16425. (528 aa)
CBG16422Protein CBG16422. (1450 aa)
fbxl-1Protein CBG16659. (465 aa)
rpn-6.1Protein CBR-RPN-6.1. (404 aa)
rfl-1Protein CBR-RFL-1. (430 aa)
CBG16572Protein CBG16572. (324 aa)
CBG16582Protein CBG16582. (228 aa)
CBG16798Protein CBG16798. (630 aa)
CBG17040Protein CBG17040. (663 aa)
CBG17039Protein CBG17039; Belongs to the cullin family. (719 aa)
CBG17038Protein CBG17038; Belongs to the cullin family. (771 aa)
CBG17150Protein CBG17150. (659 aa)
vhl-1Protein CBR-VHL-1. (170 aa)
CBG17431Protein CBG17431. (158 aa)
CBG17459Protein CBG17459. (547 aa)
CBG17703Protein CBG17703. (296 aa)
cul-2Protein CBR-CUL-2; Belongs to the cullin family. (850 aa)
cul-1Protein CBR-CUL-1; Belongs to the cullin family. (768 aa)
CBG18387Protein CBG18387. (1807 aa)
CBG17991Protein CBG17991. (622 aa)
CBG18037Protein CBG18037. (490 aa)
rpn-3Protein CBR-RPN-3. (506 aa)
ula-1NEDD8-activating enzyme E1 regulatory subunit. (550 aa)
ubc-12Protein CBR-UBC-12; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
ubh-3Ubiquitin carboxyl-terminal hydrolase. (242 aa)
ubh-1Ubiquitin carboxyl-terminal hydrolase. (216 aa)
CBG18955Protein CBG18955. (148 aa)
rbx-1Protein CBR-RBX-1. (110 aa)
CBG19367Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (239 aa)
CBG19533Protein CBG19533. (313 aa)
CBG19642Protein CBG19642. (306 aa)
CBG19647Protein CBG19647; Belongs to the cullin family. (528 aa)
rpn-13Protein CBG19693. (375 aa)
CBG19694Protein CBG19694. (143 aa)
pbs-5Protein CBR-PBS-5. (284 aa)
skn-1Protein CBR-SKN-1. (611 aa)
csn-5Protein CBR-CSN-5. (367 aa)
mec-15Protein CBG20219. (368 aa)
csa-1Protein CBG20232. (348 aa)
CBG21708Protein CBG21708. (303 aa)
rpn-7Protein CBR-RPN-7. (409 aa)
csn-2Protein CBR-CSN-2. (368 aa)
CBG22161Protein CBG22161. (153 aa)
adpr-1Protein CBR-ADPR-1. (533 aa)
CBG22545Protein CBG22545. (478 aa)
dcaf-1Protein CBG22664. (2566 aa)
CBG22716Protein CBG22716. (460 aa)
rpt-1Protein CBR-RPT-1; Belongs to the AAA ATPase family. (435 aa)
maf-1Protein CBR-MAF-1. (172 aa)
CBG25600Protein CBG25600. (155 aa)
CBG25234Protein CBG25234. (347 aa)
CBG27741Protein CBG27741; Belongs to the cullin family. (134 aa)
CBG26557Protein CBG26557. (159 aa)
CBG19761Protein CBG19761. (250 aa)
Cbr-spsb-2Protein CBR-SPSB-2. (493 aa)
CBG20339Protein CBG20339; Belongs to the AAA ATPase family. (415 aa)
png-1Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins [...] (602 aa)
dcn-1Defective in cullin neddylation protein 1; Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes (By similarity). (367 aa)
sel-10F-box/WD repeat-containing protein sel-10; Probable substrate recognition component of SCF (SKP1-CUL-F- box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates synapse elimination in early development in the motor neuron HSNL. Cell autonomous negative regulator of lin-12/Notch- mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis. May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation. Involved in sex determi [...] (589 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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