STRINGSTRING
CBG23781 CBG23781 cand-1 cand-1 Cbr-skr-10 Cbr-skr-10 CBG00496 CBG00496 CBG00897 CBG00897 CBG01819 CBG01819 CBG02202 CBG02202 kel-1 kel-1 lin-23 lin-23 lrr-1 lrr-1 skr-1 skr-1 skr-20 skr-20 skr-19 skr-19 skr-21 skr-21 skr-16 skr-16 cul-3 cul-3 kel-8 kel-8 CBG08898 CBG08898 CBG09040 CBG09040 CBG09125 CBG09125 CBG09126 CBG09126 cul-5 cul-5 CBG09938 CBG09938 CBG10989 CBG10989 elc-1 elc-1 kel-20 kel-20 CBG11949 CBG11949 rbx-2 rbx-2 ned-8 ned-8 skr-17 skr-17 CBG12958 CBG12958 elb-1 elb-1 CBG14875 CBG14875 CBG14876 CBG14876 CBG15156 CBG15156 CBG15626 CBG15626 CBG16425 CBG16425 CBG16422 CBG16422 fbxl-1 fbxl-1 rfl-1 rfl-1 CBG17039 CBG17039 CBG17038 CBG17038 CBG17150 CBG17150 vhl-1 vhl-1 cul-2 cul-2 cul-1 cul-1 ula-1 ula-1 ubc-12 ubc-12 rbx-1 rbx-1 CBG19533 CBG19533 CBG19647 CBG19647 skn-1 skn-1 mec-15 mec-15 CBG22545 CBG22545 CBG22716 CBG22716 maf-1 maf-1 CBG27741 CBG27741 CBG19761 CBG19761 dcn-1 dcn-1 sel-10 sel-10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG23781Protein CBG23781. (367 aa)
cand-1Protein CBR-CAND-1. (1124 aa)
Cbr-skr-10Protein CBR-SKR-10; Belongs to the SKP1 family. (196 aa)
CBG00496Protein CBG00496; Belongs to the SKP1 family. (198 aa)
CBG00897Protein CBG00897. (589 aa)
CBG01819Protein CBG01819. (418 aa)
CBG02202Protein CBG02202; Belongs to the SKP1 family. (174 aa)
kel-1Protein CBR-KEL-1. (615 aa)
lin-23Protein CBR-LIN-23. (682 aa)
lrr-1Protein CBR-LRR-1. (454 aa)
skr-1Protein CBR-SKR-1; Belongs to the SKP1 family. (172 aa)
skr-20Protein CBR-SKR-20; Belongs to the SKP1 family. (165 aa)
skr-19Protein CBR-SKR-19; Belongs to the SKP1 family. (162 aa)
skr-21Protein CBR-SKR-21; Belongs to the SKP1 family. (166 aa)
skr-16Protein CBR-SKR-16; Belongs to the SKP1 family. (181 aa)
cul-3Protein CBR-CUL-3; Belongs to the cullin family. (810 aa)
kel-8Protein CBR-KEL-8. (677 aa)
CBG08898Protein CBG08898; Belongs to the SKP1 family. (161 aa)
CBG09040Protein CBG09040; Belongs to the SKP1 family. (186 aa)
CBG09125Protein CBG09125; Belongs to the SKP1 family. (197 aa)
CBG09126Protein CBG09126; Belongs to the SKP1 family. (203 aa)
cul-5Protein CBR-CUL-5; Belongs to the cullin family. (766 aa)
CBG09938Protein CBG09938. (296 aa)
CBG10989Protein CBG10989; Belongs to the SKP1 family. (208 aa)
elc-1Protein CBR-ELC-1; Belongs to the SKP1 family. (123 aa)
kel-20Protein CBG12093. (599 aa)
CBG11949Protein CBG11949; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
rbx-2Protein CBR-RBX-2. (115 aa)
ned-8Protein CBR-NED-8. (76 aa)
skr-17Protein CBR-SKR-17; Belongs to the SKP1 family. (177 aa)
CBG12958Protein CBG12958; Belongs to the SKP1 family. (161 aa)
elb-1Protein CBR-ELB-1. (117 aa)
CBG14875Protein CBG14875; Belongs to the SKP1 family. (154 aa)
CBG14876Protein CBG14876; Belongs to the SKP1 family. (149 aa)
CBG15156Protein CBG15156; Belongs to the SKP1 family. (335 aa)
CBG15626Protein CBG15626; Belongs to the SKP1 family. (208 aa)
CBG16425Protein CBG16425. (528 aa)
CBG16422Protein CBG16422. (1450 aa)
fbxl-1Protein CBG16659. (465 aa)
rfl-1Protein CBR-RFL-1. (430 aa)
CBG17039Protein CBG17039; Belongs to the cullin family. (719 aa)
CBG17038Protein CBG17038; Belongs to the cullin family. (771 aa)
CBG17150Protein CBG17150. (659 aa)
vhl-1Protein CBR-VHL-1. (170 aa)
cul-2Protein CBR-CUL-2; Belongs to the cullin family. (850 aa)
cul-1Protein CBR-CUL-1; Belongs to the cullin family. (768 aa)
ula-1NEDD8-activating enzyme E1 regulatory subunit. (550 aa)
ubc-12Protein CBR-UBC-12; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
rbx-1Protein CBR-RBX-1. (110 aa)
CBG19533Protein CBG19533. (313 aa)
CBG19647Protein CBG19647; Belongs to the cullin family. (528 aa)
skn-1Protein CBR-SKN-1. (611 aa)
mec-15Protein CBG20219. (368 aa)
CBG22545Protein CBG22545. (478 aa)
CBG22716Protein CBG22716. (460 aa)
maf-1Protein CBR-MAF-1. (172 aa)
CBG27741Protein CBG27741; Belongs to the cullin family. (134 aa)
CBG19761Protein CBG19761. (250 aa)
dcn-1Defective in cullin neddylation protein 1; Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with rbx-1 to recruit the Nedd8-charged E2 enzyme to the cullin component of SCF-type complexes (By similarity). (367 aa)
sel-10F-box/WD repeat-containing protein sel-10; Probable substrate recognition component of SCF (SKP1-CUL-F- box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates synapse elimination in early development in the motor neuron HSNL. Cell autonomous negative regulator of lin-12/Notch- mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis. May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation. Involved in sex determi [...] (589 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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