STRINGSTRING
cand-1 cand-1 lin-23 lin-23 skr-1 skr-1 skr-20 skr-20 skr-19 skr-19 skr-16 skr-16 CBG09125 CBG09125 CBG17038 CBG17038 CBG17150 CBG17150 cul-1 cul-1 CBG27741 CBG27741 sel-10 sel-10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cand-1Protein CBR-CAND-1. (1124 aa)
lin-23Protein CBR-LIN-23. (682 aa)
skr-1Protein CBR-SKR-1; Belongs to the SKP1 family. (172 aa)
skr-20Protein CBR-SKR-20; Belongs to the SKP1 family. (165 aa)
skr-19Protein CBR-SKR-19; Belongs to the SKP1 family. (162 aa)
skr-16Protein CBR-SKR-16; Belongs to the SKP1 family. (181 aa)
CBG09125Protein CBG09125; Belongs to the SKP1 family. (197 aa)
CBG17038Protein CBG17038; Belongs to the cullin family. (771 aa)
CBG17150Protein CBG17150. (659 aa)
cul-1Protein CBR-CUL-1; Belongs to the cullin family. (768 aa)
CBG27741Protein CBG27741; Belongs to the cullin family. (134 aa)
sel-10F-box/WD repeat-containing protein sel-10; Probable substrate recognition component of SCF (SKP1-CUL-F- box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates synapse elimination in early development in the motor neuron HSNL. Cell autonomous negative regulator of lin-12/Notch- mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis. May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation. Involved in sex determi [...] (589 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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