(38 nodes) COPI-mediated anterograde transport, and Sec7/BIG1-like, C-terminal domain network (Caenorhabditis briggsae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG23822	Protein CBG23822. (313 aa)
	CBG24292	Protein CBG24292. (157 aa)
	tmed-4	Protein CBG24517. (212 aa)
	CBG00309	Protein CBG00309. (550 aa)
	arf-6	Protein CBR-ARF-6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	arl-1	Protein CBR-ARL-1; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	CBG01545	Protein CBG01545. (557 aa)
	CBG03185	Protein CBG03185. (160 aa)
	CBG02397	Protein CBG02397. (521 aa)
	golg-2	Protein CBG02303. (941 aa)
	copg-1	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (884 aa)
	mam-2	Protein CBR-MAM-2. (759 aa)
	copa-1	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1230 aa)
	CBG09088	Protein CBG09088. (291 aa)
	erd-2.2	ER lumen protein-retaining receptor. (213 aa)
	arl-5	Protein CBR-ARL-5; Belongs to the small GTPase superfamily. Arf family. (177 aa)
	CBG10089	Protein CBG10089. (291 aa)
	CBG11238	Protein CBG11238. (1525 aa)
	CBG11318	Protein CBG11318. (385 aa)
	CBG11316	Protein CBG11316. (495 aa)
	sel-9	Protein CBR-SEL-9. (203 aa)
	unc-108	Protein CBR-UNC-108. (214 aa)
	CBG12524	Protein CBG12524. (421 aa)
	tmed-3	Protein CBG12656. (203 aa)
	gbf-1	Protein CBR-GBF-1. (1990 aa)
	CBG13231	Protein CBG13231. (313 aa)
	CBG13235	Protein CBG13235. (289 aa)
	sft-4	Protein CBR-SFT-4. (277 aa)
	copd-1	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (514 aa)
	arf-3	Protein CBR-ARF-3; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	copb-1	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (964 aa)
	agef-1	Protein CBR-AGEF-1. (1619 aa)
	sql-1	Protein CBG20118. (1233 aa)
	cope-1	Protein CBG21210. (335 aa)
	copb-2	Protein CBG21666. (1018 aa)
	tmed-10	Protein CBG23171. (204 aa)
	arl-6	ADP-ribosylation factor-like protein 6. (190 aa)
	arf-1.2	ADP-ribosylation factor 1-like 2; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Involved in endoplasmic reticulum dynamics during embryogenesis. Also required for adult germline function (By similarity); Belongs to the small GTPase superfamily. Arf family. (181 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00309	CBG01545	A8WMN9	A8WRE7	Protein CBG00309.	Protein CBG01545.	0.531
CBG00309	CBG09088	A8WMN9	A8X7U0	Protein CBG00309.	Protein CBG09088.	0.517
CBG00309	golg-2	A8WMN9	A8WUM7	Protein CBG00309.	Protein CBG02303.	0.477
CBG00309	sql-1	A8WMN9	A8XX46	Protein CBG00309.	Protein CBG20118.	0.587
CBG01545	CBG00309	A8WRE7	A8WMN9	Protein CBG01545.	Protein CBG00309.	0.531
CBG01545	CBG03185	A8WRE7	A8WSL4	Protein CBG01545.	Protein CBG03185.	0.746
CBG01545	CBG09088	A8WRE7	A8X7U0	Protein CBG01545.	Protein CBG09088.	0.992
CBG01545	CBG11316	A8WRE7	A8XDA9	Protein CBG01545.	Protein CBG11316.	0.432
CBG01545	CBG11318	A8WRE7	A8XDA8	Protein CBG01545.	Protein CBG11318.	0.432
CBG01545	CBG13231	A8WRE7	A8XHC8	Protein CBG01545.	Protein CBG13231.	0.404
CBG01545	CBG13235	A8WRE7	A8XHD2	Protein CBG01545.	Protein CBG13235.	0.404
CBG01545	CBG23822	A8WRE7	A8WJD5	Protein CBG01545.	Protein CBG23822.	0.746
CBG01545	CBG24292	A8WRE7	A8WKE2	Protein CBG01545.	Protein CBG24292.	0.746
CBG01545	arf-3	A8WRE7	A8XRF4	Protein CBG01545.	Protein CBR-ARF-3; Belongs to the small GTPase superfamily. Arf family.	0.403
CBG01545	arl-1	A8WRE7	A8WNL4	Protein CBG01545.	Protein CBR-ARL-1; Belongs to the small GTPase superfamily. Arf family.	0.597
CBG01545	copb-1	A8WRE7	A8XW26	Protein CBG01545.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.510
CBG01545	copb-2	A8WRE7	A8Y0S9	Protein CBG01545.	Protein CBG21666.	0.404
CBG01545	copd-1	A8WRE7	A8XLP9	Protein CBG01545.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.567
CBG01545	copg-1	A8WRE7	A8WUZ6	Protein CBG01545.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.513
CBG01545	erd-2.2	A8WRE7	A8X7Y1	Protein CBG01545.	ER lumen protein-retaining receptor.	0.417