STRINGSTRING
vps-11 vps-11 vps-39 vps-39 vps-8 vps-8 ccz-1 ccz-1 vps-18 vps-18 vps-33.1 vps-33.1 sand-1 sand-1 rab-7 rab-7 vps-16 vps-16 vps-41 vps-41
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vps-11Vacuolar protein sorting-associated protein 11 homolog; Belongs to the VPS11 family. (981 aa)
vps-39Protein CBG04769. (949 aa)
vps-8Protein CBG06265. (1275 aa)
ccz-1Protein CBR-CCZ-1. (530 aa)
vps-18Protein CBG13485. (940 aa)
vps-33.1Protein CBR-VPS-33.1; Belongs to the STXBP/unc-18/SEC1 family. (605 aa)
sand-1Protein CBR-SAND-1. (460 aa)
rab-7Protein CBR-RAB-7. (209 aa)
vps-16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal mem [...] (858 aa)
vps-41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane [...] (898 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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