STRINGSTRING
sly-1 sly-1 pgap-2 pgap-2 gly-6 gly-6 CBG18701 CBG18701 nstp-10 nstp-10 Cbr-sqv-2 Cbr-sqv-2 copb-1 copb-1 aex-5 aex-5 dhhc-13 dhhc-13 nbet-1 nbet-1 rei-1 rei-1 rnf-121 rnf-121 scp-1 scp-1 rab-39 rab-39 gly-18 gly-18 eas-1 eas-1 gly-1 gly-1 mig-14 mig-14 cope-1 cope-1 CBG21363 CBG21363 nstp-1 nstp-1 gly-7 gly-7 gly-10 gly-10 dhhc-14 dhhc-14 CBG22730 CBG22730 gly-11 gly-11 gly-5 gly-5 bre-2.1 bre-2.1 bre-2.2 bre-2.2 CBG23370 CBG23370 CBG23369 CBG23369 mans-2 mans-2 aman-2 aman-2 syx-5 syx-5 gly-20 gly-20 CBG26397 CBG26397 CBG26362 CBG26362 CBG26903 CBG26903 CBG25821 CBG25821 CBG00660 CBG00660 CBG11233 CBG11233 CBG24931 CBG24931 nglcat2 nglcat2 sqv-8 sqv-8 sqv-6 sqv-6 hst-1 hst-1 hpd-1 hpd-1 mig-23 mig-23 pst-2 pst-2 cogc-6.2 cogc-6.2 wee-1.3 wee-1.3 CBG00291 CBG00291 CBG00309 CBG00309 CBG00477 CBG00477 hut-1 hut-1 cogc-2 cogc-2 CBG00683 CBG00683 CBG00645 CBG00645 CBG00952 CBG00952 uso-1 uso-1 CBG01704 CBG01704 cogc-8 cogc-8 CBG01918 CBG01918 CBG02142 CBG02142 CBG02175 CBG02175 CBG12134 CBG12134 gly-3 gly-3 aman-3 aman-3 CBG12524 CBG12524 bli-4 bli-4 rab-10 rab-10 gly-2 gly-2 pen-2 pen-2 gly-9 gly-9 gly-8 gly-8 maa-1 maa-1 chst-1 chst-1 swt-1 swt-1 bus-2 bus-2 CBG13585 CBG13585 CBG13626 CBG13626 CBG13772 CBG13772 CBG14086 CBG14086 CBG14281 CBG14281 CBG14622 CBG14622 CBG14940 CBG14940 cav-1 cav-1 nstp-6 nstp-6 CBG15025 CBG15025 CBG15066 CBG15066 copd-1 copd-1 gos-28 gos-28 pod-1 pod-1 kpc-1 kpc-1 bgnt-1.2 bgnt-1.2 memb-1 memb-1 CBG16685 CBG16685 odr-4 odr-4 CBG16794 CBG16794 CBG16873 CBG16873 hst-2 hst-2 lge-1 lge-1 ntp-1 ntp-1 rib-2 rib-2 CBG11978 CBG11978 hop-1 hop-1 unc-108 unc-108 mans-1 mans-1 sms-3 sms-3 sel-9 sel-9 CBG11316 CBG11316 CBG11318 CBG11318 Cbr-cogc-6.2 Cbr-cogc-6.2 sqv-7 sqv-7 CBG11221 CBG11221 exl-1 exl-1 ceh-44 ceh-44 CBG09782 CBG09782 sftd-3 sftd-3 rer-1 rer-1 fut-1 fut-1 CBG03022 CBG03022 CBG02772 CBG02772 casy-1 casy-1 CBG02521 CBG02521 CBG02397 CBG02397 copg-1 copg-1 tpst-1 tpst-1 copa-1 copa-1 ile-1 ile-1 gly-15 gly-15 yif-1 yif-1 nstp-2 nstp-2 CBG06249 CBG06249 pgap-3 pgap-3 pst-1 pst-1 nstp-3 nstp-3 CBG09465 CBG09465 CBG09575 CBG09575 CBG09088 CBG09088 glct-6 glct-6 CBG08283 CBG08283 ile-2 ile-2 sel-12 sel-12 sms-2 sms-2 vps-45 vps-45 sec-22 sec-22 pmr-1 pmr-1 CBG07338 CBG07338 rab-14 rab-14 erv-46 erv-46 bus-17 bus-17 nstp-4 nstp-4 sms-5 sms-5 cogc-4 cogc-4 ugtp-1 ugtp-1 cav-2 cav-2 CBG06588 CBG06588 CBG05724 CBG05724 CBG05725 CBG05725 CBG05781 CBG05781 sms-1 sms-1 bre-5 bre-5 unc-50 unc-50 gly-4 gly-4 CBG24500 CBG24500 nstp-5 nstp-5 srf-3 srf-3 CBG23731 CBG23731
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sly-1Protein CBG18370; Belongs to the STXBP/unc-18/SEC1 family. (720 aa)
pgap-2Post-GPI attachment to proteins factor 2; Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface (By similarity); Belongs to the PGAP2 family. (263 aa)
gly-6Polypeptide N-acetylgalactosaminyltransferase. (653 aa)
CBG18701Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (543 aa)
nstp-10Protein CBR-NSTP-10. (349 aa)
Cbr-sqv-2Protein CBR-SQV-2. (562 aa)
copb-1Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (964 aa)
aex-5Protein CBR-AEX-5. (541 aa)
dhhc-13Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (592 aa)
nbet-1Protein CBR-NBET-1. (106 aa)
rei-1Protein CBG20214. (245 aa)
rnf-121Protein CBR-RNF-121. (332 aa)
scp-1Protein CBR-SCP-1. (1102 aa)
rab-39Protein CBR-RAB-39. (199 aa)
gly-18Protein CBR-GLY-18. (435 aa)
eas-1Protein CBG20627. (90 aa)
gly-1Protein CBR-GLY-1. (355 aa)
mig-14Protein CBR-MIG-14. (548 aa)
cope-1Protein CBG21210. (335 aa)
CBG21363Protein CBG21363. (375 aa)
nstp-1Protein CBR-NSTP-1. (318 aa)
gly-7Polypeptide N-acetylgalactosaminyltransferase. (606 aa)
gly-10Putative polypeptide N-acetylgalactosaminyltransferase 10; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. (629 aa)
dhhc-14Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (593 aa)
CBG22730Protein transport protein sec16. (1858 aa)
gly-11Polypeptide N-acetylgalactosaminyltransferase. (619 aa)
gly-5Polypeptide N-acetylgalactosaminyltransferase. (712 aa)
bre-2.1Beta-1,3-galactosyltransferase bre-2; Transfers N-acetylgalactosamine onto carbohydrate substrates. Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-1, bre-3, bre-4, and bre-5. Involved in resistance to the nematotoxic C.cinerea galectin Cgl2. (365 aa)
bre-2.2Hexosyltransferase. (422 aa)
CBG23370Protein CBG23370. (487 aa)
CBG23369Protein CBG23369. (596 aa)
mans-2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (575 aa)
aman-2Protein CBR-AMAN-2. (1153 aa)
syx-5Protein CBR-SYX-5; Belongs to the syntaxin family. (378 aa)
gly-20Protein CBR-GLY-20. (495 aa)
CBG26397Protein CBG26397. (78 aa)
CBG26362Golgi apparatus membrane protein TVP23 homolog. (222 aa)
CBG26903Protein CBG26903. (253 aa)
CBG25821Protein CBG25821. (152 aa)
CBG00660Protein CBG00660. (361 aa)
CBG11233Protein CBG11233. (292 aa)
CBG24931Protein CBG24931. (858 aa)
nglcat2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (306 aa)
sqv-8Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (356 aa)
sqv-6Xylosyltransferase sqv-6; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes; Belongs to the glycosyltransferase 14 family. XylT subfamily. (803 aa)
hst-1Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis (By similarity); Belongs to the sulfotransferase 1 family. NDST subfamily. (859 aa)
hpd-14-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family. (393 aa)
mig-23Nucleoside-diphosphatase mig-23; Seems to be able to hydrolyze ADP, UDP and GDP. Supports mig- 17 glycosylation and surface expression, which is required for proper migration of distal tip cells during gonad morphogenesis (By similarity). (553 aa)
pst-2Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi (By similarity); Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. (363 aa)
cogc-6.2Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (638 aa)
wee-1.3Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. (656 aa)
CBG00291Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (162 aa)
CBG00309Protein CBG00309. (550 aa)
CBG00477Protein CBG00477. (381 aa)
hut-1Protein CBR-HUT-1. (354 aa)
cogc-2Protein CBR-COGC-2. (684 aa)
CBG00683Protein CBG00683. (1182 aa)
CBG00645Protein CBG00645. (357 aa)
CBG00952Protein CBG00952. (337 aa)
uso-1Protein CBG01765. (952 aa)
CBG01704Protein CBG01704. (280 aa)
cogc-8Protein CBR-COGC-8. (232 aa)
CBG01918Protein CBG01918. (301 aa)
CBG02142Sulfhydryl oxidase. (590 aa)
CBG02175Protein CBG02175. (285 aa)
CBG12134Protein CBG12134. (342 aa)
gly-3Polypeptide N-acetylgalactosaminyltransferase. (611 aa)
aman-3Alpha-mannosidase. (1084 aa)
CBG12524Protein CBG12524. (421 aa)
bli-4Protein CBR-BLI-4; Belongs to the peptidase S8 family. (730 aa)
rab-10Protein CBR-RAB-10. (201 aa)
gly-2Protein CBR-GLY-2. (671 aa)
pen-2Protein CBR-PEN-2. (101 aa)
gly-9Polypeptide N-acetylgalactosaminyltransferase. (580 aa)
gly-8Protein CBR-GLY-8. (430 aa)
maa-1Protein CBR-MAA-1. (280 aa)
chst-1Protein CBG13336. (330 aa)
swt-1Sugar transporter SWEET1; Mediates both low-affinity uptake and efflux of sugar across the membrane; Belongs to the SWEET sugar transporter family. (293 aa)
bus-2Hexosyltransferase. (320 aa)
CBG13585Protein CBG13585. (107 aa)
CBG13626Protein CBG13626. (68 aa)
CBG13772Protein CBG13772. (449 aa)
CBG14086Protein CBG14086. (493 aa)
CBG14281Sulfhydryl oxidase. (681 aa)
CBG14622Protein CBG14622. (380 aa)
CBG14940Protein CBG14940. (284 aa)
cav-1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa)
nstp-6Protein CBR-NSTP-6. (384 aa)
CBG15025Protein CBG15025. (115 aa)
CBG15066Protein CBG15066. (297 aa)
copd-1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (514 aa)
gos-28Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. Cooperates with ykt-6 for proper expression of Golgi-resident proteins. Required along with ykt-6 for normal embryonic development, seam cell division or differentiation, and ray formation (By similarity). (234 aa)
pod-1Protein CBR-POD-1. (1118 aa)
kpc-1Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
bgnt-1.2Protein CBG15889. (316 aa)
memb-1Golgi SNAP receptor complex member 2 homolog memb-1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa)
CBG16685Protein CBG16685. (398 aa)
odr-4Protein CBR-ODR-4. (450 aa)
CBG16794Polypeptide N-acetylgalactosaminyltransferase. (569 aa)
CBG16873Protein CBG16873. (208 aa)
hst-2Protein CBR-HST-2. (368 aa)
lge-1Protein CBR-LGE-1. (636 aa)
ntp-1Protein CBR-NTP-1; Belongs to the GDA1/CD39 NTPase family. (511 aa)
rib-2Protein CBR-RIB-2; Belongs to the glycosyltransferase 47 family. (877 aa)
CBG11978Protein CBG11978. (148 aa)
hop-1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
unc-108Protein CBR-UNC-108. (214 aa)
mans-1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (541 aa)
sms-3Protein CBR-SMS-3. (297 aa)
sel-9Protein CBR-SEL-9. (203 aa)
CBG11316Protein CBG11316. (495 aa)
CBG11318Protein CBG11318. (385 aa)
Cbr-cogc-6.2Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (626 aa)
sqv-7Protein CBR-SQV-7. (328 aa)
CBG11221Protein CBG11221. (453 aa)
exl-1Protein CBR-EXL-1. (241 aa)
ceh-44Homeobox protein cut-like. (1537 aa)
CBG09782Protein CBG09782. (362 aa)
sftd-3Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (201 aa)
rer-1Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (191 aa)
fut-1Protein CBR-FUT-1. (424 aa)
CBG03022Protein CBG03022. (1515 aa)
CBG02772Protein CBG02772. (299 aa)
casy-1Protein CBR-CASY-1. (983 aa)
CBG02521Protein CBG02521. (520 aa)
CBG02397Protein CBG02397. (521 aa)
copg-1Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (884 aa)
tpst-1Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (377 aa)
copa-1Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1230 aa)
ile-1Protein CBR-ILE-1. (491 aa)
gly-15Protein CBR-GLY-15. (337 aa)
yif-1Protein CBR-YIF-1. (378 aa)
nstp-2Protein CBR-NSTP-2. (324 aa)
CBG06249Sulfhydryl oxidase. (618 aa)
pgap-3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (326 aa)
pst-1Protein CBR-PST-1. (441 aa)
nstp-3Protein CBR-NSTP-3. (344 aa)
CBG09465Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (286 aa)
CBG09575Hexosyltransferase. (496 aa)
CBG09088Protein CBG09088. (291 aa)
glct-6Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (254 aa)
CBG08283Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (316 aa)
ile-2Protein CBR-ILE-2. (347 aa)
sel-12Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
sms-2Protein CBR-SMS-2. (336 aa)
vps-45Protein CBR-VPS-45; Belongs to the STXBP/unc-18/SEC1 family. (547 aa)
sec-22Protein CBR-SEC-22; Belongs to the synaptobrevin family. (214 aa)
pmr-1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (978 aa)
CBG07338Hexosyltransferase. (373 aa)
rab-14Protein CBR-RAB-14. (210 aa)
erv-46Protein CBR-ERV-46. (380 aa)
bus-17Hexosyltransferase. (214 aa)
nstp-4Protein CBR-NSTP-4. (349 aa)
sms-5Protein CBG07059. (328 aa)
cogc-4Protein CBR-COGC-4. (823 aa)
ugtp-1Protein CBR-UGTP-1. (357 aa)
cav-2Protein CBR-CAV-2. (275 aa)
CBG06588Protein CBG06588. (443 aa)
CBG05724Protein CBG05724. (486 aa)
CBG05725Protein CBG05725. (463 aa)
CBG05781Golgi apparatus membrane protein TVP23 homolog. (207 aa)
sms-1Protein CBR-SMS-1. (407 aa)
bre-5Hexosyltransferase. (281 aa)
unc-50Protein CBR-UNC-50. (306 aa)
gly-4Polypeptide N-acetylgalactosaminyltransferase. (587 aa)
CBG24500Protein CBG24500. (474 aa)
nstp-5Protein CBR-NSTP-5. (398 aa)
srf-3Protein CBR-SRF-3. (345 aa)
CBG23731Protein CBG23731. (247 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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