STRINGSTRING
wrm-1 wrm-1 end-1 end-1 src-1 src-1 mig-14 mig-14 mom-2 mom-2 end-3.2 end-3.2 dsh-2 dsh-2 mig-5 mig-5 end-3.1 end-3.1 mom-5 mom-5 tap-1 tap-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wrm-1Armadillo repeat-containing protein wrm-1; Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Activates lit-1- dependent kinase activity. Wrm-1/lit-1 complex promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome [...] (799 aa)
end-1Protein CBR-END-1. (210 aa)
src-1Tyrosine-protein kinase. (544 aa)
mig-14Protein CBR-MIG-14. (548 aa)
mom-2Protein CBR-MOM-2. (358 aa)
end-3.2Protein CBG11404. (248 aa)
dsh-2Protein CBR-DSH-2. (784 aa)
mig-5Protein CBR-MIG-5. (657 aa)
end-3.1Protein CBR-END-3. (253 aa)
mom-5Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
tap-1Protein CBR-TAP-1. (389 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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