30 items (Caenorhabditis briggsae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hop-1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
	sup-17	Protein CBR-SUP-17. (920 aa)
	CBG12386	Protein CBG12386. (2855 aa)
	pen-2	Protein CBR-PEN-2. (101 aa)
	mib-1	Protein CBR-MIB-1. (766 aa)
	dsl-3	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (259 aa)
	Cbr-nhr-146	Protein CBG13577. (196 aa)
	aph-1	Protein CBR-APH-1. (330 aa)
	lag-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (392 aa)
	CBG13578	Protein CBG13578. (340 aa)
	CBG13949	Protein CBG13949. (167 aa)
	CBG14147	Protein CBG14147; Belongs to the syntaxin family. (523 aa)
	osm-11	Protein CBR-OSM-11. (188 aa)
	adm-4	Protein CBR-ADM-4. (701 aa)
	spe-4	Protein CBR-SPE-4. (483 aa)
	CBG19473	Protein CBG19473. (96 aa)
	aph-2	Protein CBR-APH-2. (721 aa)
	dsl-1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (257 aa)
	CBG24197	Protein CBG24197. (188 aa)
	CBG24198	Protein CBG24198. (188 aa)
	lag-1	Protein CBR-LAG-1. (681 aa)
	lip-1	Protein CBR-LIP-1. (376 aa)
	glp-1	Protein CBR-GLP-1. (1326 aa)
	lin-12.2	Protein CBR-LIN-12. (1392 aa)
	CBG06829	Protein CBG06829. (987 aa)
	lin-12.1	Protein CBG06951. (1359 aa)
	CBG07064	Protein CBG07064. (477 aa)
	sel-12	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
	dsl-7	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (325 aa)
	sao-1	Protein CBG11416. (253 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG06829	adm-4	A8X360	A8XPT9	Protein CBG06829.	Protein CBR-ADM-4.	0.571
CBG06829	aph-1	A8X360	B0K098	Protein CBG06829.	Protein CBR-APH-1.	0.926
CBG06829	aph-2	A8X360	A8XZV7	Protein CBG06829.	Protein CBR-APH-2.	0.966
CBG06829	hop-1	A8X360	A8XEJ8	Protein CBG06829.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.968
CBG06829	lag-1	A8X360	A8X027	Protein CBG06829.	Protein CBR-LAG-1.	0.999
CBG06829	lag-2	A8X360	A8Y103	Protein CBG06829.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.577
CBG06829	lin-12.2	A8X360	A8X358	Protein CBG06829.	Protein CBR-LIN-12.	0.901
CBG06829	lip-1	A8X360	A8X1U3	Protein CBG06829.	Protein CBR-LIP-1.	0.580
CBG06829	osm-11	A8X360	A8XNG4	Protein CBG06829.	Protein CBR-OSM-11.	0.594
CBG06829	pen-2	A8X360	A8XHA1	Protein CBG06829.	Protein CBR-PEN-2.	0.954
CBG06829	sel-12	A8X360	A8X5S7	Protein CBG06829.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.971
CBG06829	spe-4	A8X360	G2J6Q7	Protein CBG06829.	Protein CBR-SPE-4.	0.945
CBG06829	sup-17	A8X360	A8XF96	Protein CBG06829.	Protein CBR-SUP-17.	0.969
CBG19473	aph-2	A8XVM6	A8XZV7	Protein CBG19473.	Protein CBR-APH-2.	0.963
CBG19473	hop-1	A8XVM6	A8XEJ8	Protein CBG19473.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.795
CBG19473	pen-2	A8XVM6	A8XHA1	Protein CBG19473.	Protein CBR-PEN-2.	0.961
CBG19473	sel-12	A8XVM6	A8X5S7	Protein CBG19473.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.795
CBG19473	spe-4	A8XVM6	G2J6Q7	Protein CBG19473.	Protein CBR-SPE-4.	0.795
adm-4	CBG06829	A8XPT9	A8X360	Protein CBR-ADM-4.	Protein CBG06829.	0.571
adm-4	aph-2	A8XPT9	A8XZV7	Protein CBR-ADM-4.	Protein CBR-APH-2.	0.539