Your Input: | |
| | CBG27615 | Protein CBG27615. (78 aa) |
| | CBG23609 | Protein CBG23609. (413 aa) |
| | CBG23700 | Protein CBG23700. (246 aa) |
| | CBG23705 | COA8 family protein CBG23705, mitochondrial; May be required for cytochrome c complex (COX) assembly and function, COX being the terminal component of the mitochondrial respiratory chain; Belongs to the COA8 family. (142 aa) |
| | CBG23766 | Protein CBG23766. (399 aa) |
| | CBG23809 | Protein CBG23809. (60 aa) |
| | CBG23937 | Protein CBG23937. (86 aa) |
| | CBG23942 | Protein CBG23942. (58 aa) |
| | CBG23943 | Protein CBG23943. (82 aa) |
| | CBG23944 | Protein CBG23944. (70 aa) |
| | CBG23945 | Protein CBG23945. (91 aa) |
| | rpn-11 | Protein CBR-RPN-11. (312 aa) |
| | CBG24325 | Protein CBG24325. (399 aa) |
| | CBG24327 | Protein CBG24327. (185 aa) |
| | CBG24592 | Protein CBG24592. (399 aa) |
| | CBG24598 | Protein CBG24598. (416 aa) |
| | unc-51 | Protein CBR-UNC-51. (875 aa) |
| | CBG24636 | Protein CBG24636. (770 aa) |
| | CBG24829 | Protein CBG24829. (235 aa) |
| | CBG24830 | Protein CBG24830. (451 aa) |
| | CBG24836 | Protein CBG24836. (416 aa) |
| | CBG25054 | Protein CBG25054. (126 aa) |
| | CBG25056 | Protein CBG25056. (91 aa) |
| | cyn-13 | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (332 aa) |
| | CBG00439 | Protein CBG00439. (156 aa) |
| | CBG00749 | Protein CBG00749. (267 aa) |
| | mig-5 | Protein CBR-MIG-5. (657 aa) |
| | dpl-1 | Protein CBR-DPL-1. (603 aa) |
| | CBG01307 | Protein CBG01307; Belongs to the peptidase A1 family. (389 aa) |
| | CBG01308 | Protein CBG01308; Belongs to the peptidase A1 family. (389 aa) |
| | CBG01362 | Protein CBG01362. (461 aa) |
| | CBG01364 | Protein CBG01364. (468 aa) |
| | CBG01365 | Protein CBG01365. (484 aa) |
| | CBG01375 | Protein CBG01375. (504 aa) |
| | atg-18 | Protein CBR-ATG-18. (406 aa) |
| | CBG01467 | Protein CBG01467. (383 aa) |
| | asp-13 | Protein CBG01462; Belongs to the peptidase A1 family. (387 aa) |
| | ced-3 | Protein CBR-CED-3; Belongs to the peptidase C14A family. (508 aa) |
| | pig-1 | Non-specific serine/threonine protein kinase. (704 aa) |
| | pmk-1 | Mitogen-activated protein kinase. (377 aa) |
| | sav-1 | Protein CBR-SAV-1. (390 aa) |
| | CBG02227 | Protein CBG02227. (124 aa) |
| | hlh-3 | Protein CBR-HLH-3. (168 aa) |
| | dap-3 | Protein CBR-DAP-3. (382 aa) |
| | crn-3 | Protein CBR-CRN-3. (868 aa) |
| | crn-5 | Protein CBR-CRN-5. (214 aa) |
| | cdl-1 | Protein CBR-CDL-1. (381 aa) |
| | lin-29 | Protein CBR-LIN-29. (591 aa) |
| | lgg-1 | Protein lgg. (123 aa) |
| | rbbp-5 | Protein CBG02573. (451 aa) |
| | pink-1 | Protein CBR-PINK-1. (1237 aa) |
| | uba-1 | Protein CBR-UBA-1; Belongs to the ubiquitin-activating E1 family. (1114 aa) |
| | egl-20 | Protein CBR-EGL-20. (398 aa) |
| | pis-1 | Protein CBR-PIS-1. (1052 aa) |
| | snx-1 | Protein CBR-SNX-1. (472 aa) |
| | cps-6 | Endonuclease. (310 aa) |
| | uri-1 | Protein CBR-URI-1. (447 aa) |
| | cep-1 | Transcription factor cep-1; Transcriptional activator that binds the same DNA consensus sequence as p53. Has a role in normal development to ensure proper meiotic chromosome segregation. Promotes apoptosis under conditions of cellular and genotoxic stress in response to DNA damage, hypoxia, or starvation. However, not required for DNA repair in response to UV-C or to regulate cell-cycle progression. Regulates germline apoptosis in response to DNA damage. Required for induction of ced-13 in response to DNA damage. Its pro-apoptotic activity is inhibited when bound to ape-1 in vitro (By [...] (658 aa) |
| | lin-17 | Protein CBR-LIN-17; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa) |
| | rad-51 | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (357 aa) |
| | CBG04461 | Protein CBG04461. (433 aa) |
| | egl-1 | Protein CBR-EGL-1. (110 aa) |
| | actl-1 | Protein CBG05082. (369 aa) |
| | asp-4 | Protein CBR-ASP-4; Belongs to the peptidase A1 family. (446 aa) |
| | asp-9 | Protein CBG05505; Belongs to the peptidase A1 family. (396 aa) |
| | hif-1 | Protein CBR-HIF-1. (843 aa) |
| | nhr-67 | Protein CBR-NHR-67. (423 aa) |
| | let-70 | Protein CBR-LET-70; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | cul-3 | Protein CBR-CUL-3; Belongs to the cullin family. (810 aa) |
| | CBG06449 | Protein CBG06449. (462 aa) |
| | CBG06678 | Protein CBG06678. (377 aa) |
| | ced-11 | Protein CBR-CED-11. (1480 aa) |
| | CBG07690 | Protein CBG07690. (278 aa) |
| | CBG07689 | Protein CBG07689. (293 aa) |
| | CBG07602 | Protein CBG07602. (452 aa) |
| | alkb-7 | Protein CBG07885. (228 aa) |
| | CBG07900 | Protein CBG07900. (409 aa) |
| | soem-1 | Protein CBG08021. (190 aa) |
| | aex-3 | Protein CBR-AEX-3. (1500 aa) |
| | ced-5 | Protein CBR-CED-5; Belongs to the DOCK family. (1820 aa) |
| | hrg-7 | Protein CBG08575; Belongs to the peptidase A1 family. (428 aa) |
| | CBG09061 | Protein CBG09061. (248 aa) |
| | bcl-7 | Protein CBG09049. (145 aa) |
| | dpff-1 | Protein CBR-DPFF-1. (377 aa) |
| | ubq-1 | Protein CBR-UBQ-1. (770 aa) |
| | ced-6 | Protein CBR-CED-6. (490 aa) |
| | cgh-1 | Protein CBR-CGH-1; Belongs to the DEAD box helicase family. (429 aa) |
| | tag-125 | WD repeat-containing protein tag-125. (368 aa) |
| | CBG09201 | Protein CBG09201. (110 aa) |
| | CBG09200 | Protein CBG09200. (187 aa) |
| | Cbr-wdr-5.3 | Protein CBR-WDR-5.3. (476 aa) |
| | crn-2 | Protein CBR-CRN-2. (300 aa) |
| | ced-7 | Protein CBR-CED-7. (1784 aa) |
| | crn-6 | Protein CBR-CRN-6. (380 aa) |
| | CBG09744 | Protein CBG09744. (65 aa) |
| | asp-3 | Protein CBR-ASP-3; Belongs to the peptidase A1 family. (397 aa) |
| | gei-15 | Protein CBR-GEI-15. (408 aa) |
| | CBG10901 | Protein CBG10901. (360 aa) |
| | fis-1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (143 aa) |
| | snt-1 | Protein CBR-SNT-1. (443 aa) |
| | CBG11175 | Protein CBG11175. (184 aa) |
| | unc-104 | Protein CBR-UNC-104; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1699 aa) |
| | CBG11327 | Protein CBG11327. (548 aa) |
| | CBG11306 | Protein CBG11306; Belongs to the peptidase A1 family. (370 aa) |
| | asp-6 | Protein CBR-ASP-6; Belongs to the peptidase A1 family. (389 aa) |
| | CBG11304 | Protein CBG11304; Belongs to the peptidase A1 family. (395 aa) |
| | asp-5 | Protein CBR-ASP-5; Belongs to the peptidase A1 family. (394 aa) |
| | CBG11302 | Protein CBG11302; Belongs to the peptidase A1 family. (263 aa) |
| | CBG11284 | Protein CBG11284. (426 aa) |
| | eor-1 | Protein CBR-EOR-1. (909 aa) |
| | hsp-60 | Protein CBR-HSP-60; Belongs to the chaperonin (HSP60) family. (567 aa) |
| | CBG11869 | Protein CBG11869. (106 aa) |
| | hus-1 | Checkpoint protein; Belongs to the HUS1 family. (207 aa) |
| | msh-2 | Protein CBR-MSH-2. (847 aa) |
| | lin-44 | Abnormal cell lineage protein 44; Ligand for members of the frizzled family of seven transmembrane receptors (By similarity). Affects male tail development, vulval precursor cell specification and egg laying. Involved in morphogenesis by influencing polarity of asymmetric cell divisions of the B, U, and F cells in the male, and the T cell in males and hermaphrodites. Controls spindle orientation in B-gamma cell division during male copulatory spicule development. Involved in specification of the P7.p lineage during vulval development. Has a role in providing polarity and default lin-17 [...] (341 aa) |
| | rpn-8 | Protein CBR-RPN-8. (382 aa) |
| | ced-12 | Cell death abnormality protein 12; Involved in apoptosis and necrosis. Required for the cell corpse engulfment process. Has roles in the formation of actin halos and distal tip cell migration. Plays no role in amphid axon outgrowth (By similarity). (740 aa) |
| | CBG12344 | Protein CBG12344. (242 aa) |
| | dad-1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across th [...] (113 aa) |
| | mrt-2 | Protein CBR-MRT-2. (267 aa) |
| | CBG13274 | Protein CBG13274. (168 aa) |
| | CBG13329 | Protein CBG13329. (416 aa) |
| | wah-1 | Protein CBR-WAH-1. (696 aa) |
| | CBG13553 | Protein CBG13553; Belongs to the peptidase C14A family. (593 aa) |
| | ced-2 | Cell death abnormality protein 2; Required for cell migration and engulfment of cell corpses but not for programmed cell death/apoptosis. Also has a role in the migration of the 2 gonadal distal tip cells (DTCs) (By similarity). Belongs to the CRK family. (277 aa) |
| | ndx-4 | Protein CBR-NDX-4. (137 aa) |
| | CBG13919 | Protein CBG13919. (648 aa) |
| | CBG13918 | Protein CBG13918. (107 aa) |
| | CBG14047 | Protein CBG14047. (298 aa) |
| | Cbr-crn-4 | Protein CBR-CRN-4. (298 aa) |
| | crn-4 | Protein CBG14050. (210 aa) |
| | CBG14894 | Protein CBG14894. (545 aa) |
| | crn-1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa) |
| | ced-10 | Protein CBG15031. (191 aa) |
| | CBG15077 | Protein CBG15077. (454 aa) |
| | ced-1 | Cell death abnormality protein 1; Involved in programmed cell death/apoptosis. Acts by recruiting ced-6 to phagosomes which enables actin-dependent cytoskeletal reorganization and subsequent engulfment of the apoptotic cell corpse. Has a role in the association of ppk-3 and rab-7 with the phagosomal surface which is necessary for the incorporation of lysosomes to phagosomes during phagosome maturation. Activates the expression of unfolded protein response genes, which are involved in the immune response to live bacteria (By similarity). (1134 aa) |
| | CBG16219 | Protein CBG16219. (458 aa) |
| | crn-7 | Protein CBR-CRN-7. (367 aa) |
| | CBG16787 | Protein CBG16787. (205 aa) |
| | dct-1 | BNIP3 homolog; Initiates apoptosis in a BH3-independent mechanism possibly by recruiting ced-3 to mitochondria and other cytoplasmic membranes. Has a role in lifespan and tumor growth (By similarity). Belongs to the NIP3 family. (220 aa) |
| | CBG16997 | Protein CBG16997; Belongs to the peptidase A1 family. (428 aa) |
| | swd-2.2 | Protein CBR-SWD-2.2. (324 aa) |
| | set-16 | Protein CBR-SET-16. (2526 aa) |
| | CBG18320 | Protein CBG18320. (90 aa) |
| | rpn-3 | Protein CBR-RPN-3. (506 aa) |
| | hsf-1 | Protein CBR-HSF-1. (504 aa) |
| | lst-4 | Sorting nexin; Belongs to the sorting nexin family. (595 aa) |
| | CBG18878 | Protein CBG18878. (337 aa) |
| | dre-1 | Protein CBR-DRE-1. (1045 aa) |
| | asp-2 | Protein CBR-ASP-2; Belongs to the peptidase A1 family. (704 aa) |
| | rbx-1 | Protein CBR-RBX-1. (110 aa) |
| | CBG19533 | Protein CBG19533. (313 aa) |
| | CBG19647 | Protein CBG19647; Belongs to the cullin family. (528 aa) |
| | dlc-1 | Dynein light chain. (89 aa) |
| | ces-2 | Protein CBR-CES-2. (220 aa) |
| | bec-1 | Protein CBR-BEC-1. (375 aa) |
| | drp-1 | Protein CBR-DRP-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (693 aa) |
| | eat-3 | Protein CBR-EAT-3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (969 aa) |
| | CBG20324 | Protein CBG20324. (353 aa) |
| | asp-1 | Protein CBR-ASP-1; Belongs to the peptidase A1 family. (393 aa) |
| | CBG20331 | Protein CBG20331; Belongs to the peptidase A1 family. (126 aa) |
| | CBG20332 | Protein CBG20332; Belongs to the peptidase A1 family. (385 aa) |
| | CBG20333 | Protein CBG20333. (211 aa) |
| | Cbr-mcd-1 | Protein CBR-MCD-1. (869 aa) |
| | mig-14 | Protein CBR-MIG-14. (548 aa) |
| | efl-2 | Protein CBR-EFL-2. (281 aa) |
| | mac-1 | Protein CBR-MAC-1. (826 aa) |
| | CBG21002 | Protein CBG21002. (1108 aa) |
| | cnt-1 | Protein CBR-CNT-1. (824 aa) |
| | ash-2 | Protein CBR-ASH-2. (557 aa) |
| | prmt-5 | Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (729 aa) |
| | ttr-52 | Protein CBR-TTR-52. (136 aa) |
| | cdk-5 | Protein CBR-CDK-5; Belongs to the protein kinase superfamily. (292 aa) |
| | praf-3 | PRA1 family protein. (189 aa) |
| | CBG21635 | Protein CBG21635. (285 aa) |
| | tra-3 | Protein CBR-TRA-3; Belongs to the peptidase C2 family. (646 aa) |
| | CBG21964 | Protein CBG21964. (465 aa) |
| | plep-1 | Protein CBG21963. (508 aa) |
| | CBG22013 | Protein CBG22013. (1122 aa) |
| | atm-1 | Protein CBR-ATM-1; Belongs to the PI3/PI4-kinase family. (639 aa) |
| | CBG22159 | Protein CBG22159. (91 aa) |
| | unc-57 | Protein CBR-UNC-57. (375 aa) |
| | CBG22453 | Protein CBG22453. (463 aa) |
| | klf-1 | Protein CBR-KLF-1. (558 aa) |
| | CBG22515 | Protein CBG22515; Belongs to the peptidase C14A family. (417 aa) |
| | ced-8 | Cell death abnormality protein 8; Acts downstream of ced-9 and caspase ced-3 to promote phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Regulates apoptosis kinetics during embryonic development. Not required for engulfment of germ cell corpses. (460 aa) |
| | fis-2 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (151 aa) |
| | nob-1 | Protein CBG23031. (158 aa) |
| | dcr-1 | Protein CBR-DCR-1; Belongs to the helicase family. Dicer subfamily. (2030 aa) |
| | CBG22975 | Protein CBG22975. (146 aa) |
| | ape-1 | Protein CBR-APE-1. (824 aa) |
| | CBG25496 | Protein CBG25496. (388 aa) |
| | CBG26388 | Protein CBG26388. (223 aa) |
| | CBG28141 | Mitochondrial fission process protein 1; Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity). Belongs to the MTFP1 family. (162 aa) |
| | vha-2 | V-type proton ATPase 16 kDa proteolipid subunit 2; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The in [...] (161 aa) |
| | vha-3 | V-type proton ATPase 16 kDa proteolipid subunit 3; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Involved in necrotic cell death. Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad. This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization. The in [...] (161 aa) |
| | snx-6 | Protein CBR-SNX-6. (838 aa) |
| | itr-1 | Protein CBR-ITR-1, isoform a. (2921 aa) |
| | fem-2 | Putative PP2C protein phosphatase FEM-2. (502 aa) |
| | ced-9 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. (266 aa) |
| | sir-2.1 | NAD-dependent protein deacetylase sir-2.1; NAD-dependent deacetylase. Required for a reduction of the 'Lys-16' acetylation of histone H4 (H4K16ac) on dosage-compensated X chromosomes in hermaphrodites. Functions upstream of daf-16 in the insulin-like signaling pathway, promoting daf-16 mediated transcriptional activation and increased life-span. May also regulate life-span independently of daf-16 by modulating the transcription of genes involved in the stress response of the endoplasmic reticulum (ER). Acts upstream of the nicotinic acid metabolism pathway, which may be linked to the r [...] (602 aa) |
| | ced-4 | Cell death protein 4; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to induce caspase ced-3 autoproteolytic cleavage and activation. Also forms an holoenzyme with processed ced-3 enhancing ced-3 activity. Component of the egl-1, ced-9, ced-4 and ced- 3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During [...] (569 aa) |
| | vha-10 | Probable V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Required for necrotic cell death. (126 aa) |
| | vps-41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane [...] (898 aa) |
| | vha-12 | Probable V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Required for necrotic cell death and epidermal cell fusion (By similarity). Belongs to the ATPase alpha/beta chains family. (491 aa) |
| | crt-1 | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress- induced neurodegeneration (By similarity). (396 aa) |
| | miro-1 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (637 aa) |
