Your Input: | |
| | gap-1 | Protein CBR-GAP-1. (1265 aa) |
| | rgs-7 | Protein CBR-RGS-7. (892 aa) |
| | lst-2 | Lateral signaling target protein 2; Negative regulator of epidermal growth factor receptor (EGFR) signaling. (651 aa) |
| | lon-2 | Protein CBR-LON-2. (509 aa) |
| | CBG14563 | Protein CBG14563. (283 aa) |
| | rgs-6 | Protein CBR-RGS-6. (750 aa) |
| | sft-4 | Protein CBR-SFT-4. (277 aa) |
| | kin-2 | Protein CBR-KIN-2. (366 aa) |
| | cav-1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (239 aa) |
| | osm-9 | Protein CBR-OSM-9; Belongs to the transient receptor (TC 1.A.4) family. (940 aa) |
| | lec-6 | Galectin. (146 aa) |
| | grk-2 | Protein CBR-GRK-2. (377 aa) |
| | pvf-1 | Protein CBR-PVF-1. (300 aa) |
| | CBG15416 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (470 aa) |
| | CBG15624 | Protein CBG15624; Belongs to the BI1 family. (264 aa) |
| | CBG15976 | Protein CBG15976. (609 aa) |
| | vav-1 | Protein CBR-VAV-1. (971 aa) |
| | CBG16121 | Protein CBG16121. (210 aa) |
| | gap-2 | Protein CBR-GAP-2. (824 aa) |
| | rfl-1 | Protein CBR-RFL-1. (430 aa) |
| | gar-2 | Protein CBR-GAR-2; Belongs to the G-protein coupled receptor 1 family. (659 aa) |
| | sma-9 | Protein CBR-SMA-9. (2493 aa) |
| | CBG17703 | Protein CBG17703. (296 aa) |
| | ula-1 | NEDD8-activating enzyme E1 regulatory subunit. (550 aa) |
| | fsn-1 | F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa) |
| | efl-1 | Protein CBR-EFL-1. (303 aa) |
| | ubc-12 | Protein CBR-UBC-12; Belongs to the ubiquitin-conjugating enzyme family. (180 aa) |
| | CBG18780 | Protein CBG18780. (263 aa) |
| | pry-1 | Axin-like protein pry-1; Works in parallel with axl-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Inhibits Wnt signaling, which affects tissue specific expression of Hox genes, egl- 5, lin-39 and mab-5. This in turn affects QR (postembryonic neuroblast) cell migration, vulval cell fate specification, and the development of sensory structures by the seam cell lineage. Has a role in alae V cell patterning, ray formation in the male tail and axon guidance. Does not affect B cell polarity (By similarity). (625 aa) |
| | eya-1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (483 aa) |
| | spe-49 | Protein CBG18903. (783 aa) |
| | gck-1 | Protein CBR-GCK-1. (898 aa) |
| | CBG19258 | Protein CBG19258. (513 aa) |
| | rbx-1 | Protein CBR-RBX-1. (110 aa) |
| | xbx-6 | Protein CBR-XBX-6; Belongs to the BI1 family. (297 aa) |
| | Cbr-tag-120 | Protein CBR-TAG-120; Belongs to the BI1 family. (241 aa) |
| | unc-122 | Protein CBR-UNC-122. (555 aa) |
| | kin-19 | Protein CBR-KIN-19; Belongs to the protein kinase superfamily. (342 aa) |
| | CBG20255 | Protein CBG20255. (163 aa) |
| | pde-1 | Phosphodiesterase. (662 aa) |
| | ant-1.2 | Protein CBG20451; Belongs to the mitochondrial carrier (TC 2.A.29) family. (216 aa) |
| | crml-1 | Protein CBR-CRML-1. (1054 aa) |
| | CBG20630 | Protein CBG20630. (305 aa) |
| | CBG20633 | Protein CBG20633. (370 aa) |
| | CBG20722 | Protein CBG20722. (176 aa) |
| | CBG20723 | Protein CBG20723. (160 aa) |
| | CBG20724 | Protein CBG20724. (162 aa) |
| | CBG20725 | Protein CBG20725. (188 aa) |
| | daf-5 | Protein CBR-DAF-5. (720 aa) |
| | pde-3 | Phosphodiesterase. (504 aa) |
| | CBG21002 | Protein CBG21002. (1108 aa) |
| | prmt-5 | Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (729 aa) |
| | kin-18 | Protein CBR-KIN-18. (743 aa) |
| | CBG21231 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (461 aa) |
| | CBG21229 | Protein CBG21229. (1384 aa) |
| | ant-1.1 | Protein CBR-TAG-61; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa) |
| | CBG21259 | Protein CBG21259; Belongs to the BI1 family. (292 aa) |
| | paqr-3 | Protein CBR-PAQR-3. (326 aa) |
| | nrfl-1 | Protein CBR-TAG-60. (459 aa) |
| | rap-1 | Protein CBR-RAP-1. (188 aa) |
| | CBG22013 | Protein CBG22013. (1122 aa) |
| | atm-1 | Protein CBR-ATM-1; Belongs to the PI3/PI4-kinase family. (639 aa) |
| | gap-3 | Protein CBG22075. (960 aa) |
| | gsa-1 | Protein CBR-GSA-1. (326 aa) |
| | tln-1 | Protein CBG22153. (1036 aa) |
| | CBG22464 | Protein CBG22464. (603 aa) |
| | CBG22476 | Protein CBG22476. (413 aa) |
| | pptr-1 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (531 aa) |
| | txbp-3 | Protein CBG23021. (124 aa) |
| | sel-1 | Protein CBR-SEL-1. (685 aa) |
| | egl-10 | Protein CBR-EGL-10. (549 aa) |
| | CBG23299 | Protein CBG23299. (359 aa) |
| | CBG23254 | Protein CBG23254. (203 aa) |
| | nphp-4 | Protein CBR-NPHP-4. (1152 aa) |
| | CBG18724 | Protein CBG18724. (3212 aa) |
| | CBG27575 | Protein CBG27575. (40 aa) |
| | CBG26587 | Protein CBG26587. (599 aa) |
| | CBG25672 | Protein CBG25672. (72 aa) |
| | CBG25184 | Protein CBG25184. (1573 aa) |
| | CBG25825 | Protein CBG25825. (145 aa) |
| | CBG00051 | Protein CBG00051. (907 aa) |
| | CBG19761 | Protein CBG19761. (250 aa) |
| | gei-4 | Protein CBR-GEI-4, isoform a. (594 aa) |
| | ced-9 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. (266 aa) |
| | ric-8 | Synembryn; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins independently of G-protein coupled receptors. Acts by exchanging bound GDP for free GTP. Also able to activate the G(s)-alpha in synaptic signaling network. Plays a key role in asymmetric spindle positioning, a step for asymmetric cell division that generates cell diversity during development by activating G(i) alpha protein goa-1 and gpa-16 independently of G-protein coupled receptors (By similarity); Belongs to the synembryn family. (567 aa) |
| | sel-10 | F-box/WD repeat-containing protein sel-10; Probable substrate recognition component of SCF (SKP1-CUL-F- box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates synapse elimination in early development in the motor neuron HSNL. Cell autonomous negative regulator of lin-12/Notch- mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis. May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation. Involved in sex determi [...] (589 aa) |
| | CBG05150 | Protein CBG05150. (216 aa) |
| | CBG04910 | Protein CBG04910. (355 aa) |
| | hda-1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa) |
| | abl-1 | Tyrosine-protein kinase. (1211 aa) |
| | eat-16 | Protein CBR-EAT-16. (485 aa) |
| | Cbr-tag-316 | Protein CBR-TAG-316; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa) |
| | riok-1 | Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (515 aa) |
| | unc-37 | Protein CBR-UNC-37. (604 aa) |
| | stam-1 | Protein CBR-STAM-1. (471 aa) |
| | sesn-1 | Protein CBG03915. (557 aa) |
| | CBG03616 | Protein CBG03616. (379 aa) |
| | tir-1 | Protein CBR-TIR-1. (585 aa) |
| | CBG03609 | Protein CBG03609. (174 aa) |
| | CBG03606 | Protein CBG03606. (414 aa) |
| | pat-3 | Integrin beta; Belongs to the integrin beta chain family. (818 aa) |
| | magu-4 | Protein CBG03433. (1114 aa) |
| | CBG03383 | Protein CBG03383. (567 aa) |
| | eel-1 | Protein CBR-EEL-1. (4188 aa) |
| | shc-2 | Protein CBR-SHC-2. (620 aa) |
| | vhp-1 | Protein CBR-VHP-1. (672 aa) |
| | clr-1 | Protein CBR-CLR-1. (1471 aa) |
| | rgs-3 | Protein CBR-RGS-3. (364 aa) |
| | CBG02576 | Protein CBG02576. (393 aa) |
| | CBG02604 | Protein CBG02604. (922 aa) |
| | CBG02810 | Protein CBG02810. (320 aa) |
| | CBG02812 | Protein CBG02812. (389 aa) |
| | CBG02817 | Protein CBG02817. (157 aa) |
| | trr-1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions. Required for spermatogenesis and embryonic development. Acts with tra-2 to promote expression of fog-3 and control male tail development. Involved in the negative regulation of vulval development (By similarity). (4115 aa) |
| | CBG02060 | Protein CBG02060. (342 aa) |
| | unc-2 | Protein CBR-UNC-2. (1536 aa) |
| | gbb-1 | Protein CBG02016. (933 aa) |
| | CBG01923 | Protein CBG01923. (2041 aa) |
| | nprl-3 | Protein CBG01588. (490 aa) |
| | gbb-2 | Protein CBG01699; Belongs to the G-protein coupled receptor 3 family. (738 aa) |
| | CBG01721 | Protein CBG01721. (151 aa) |
| | smk-1 | Protein CBR-SMK-1. (1124 aa) |
| | dpl-1 | Protein CBR-DPL-1. (603 aa) |
| | CBG00683 | Protein CBG00683. (1182 aa) |
| | ttx-3 | Protein CBR-TTX-3. (380 aa) |
| | odr-7 | Protein CBR-ODR-7. (446 aa) |
| | rgs-2 | Protein CBR-RGS-2. (174 aa) |
| | CBG24891 | Protein CBG24891. (259 aa) |
| | goa-1 | Protein CBR-GOA-1. (323 aa) |
| | CBG24622 | Protein CBG24622. (139 aa) |
| | CBG23918 | Protein CBG23918. (151 aa) |
| | CBG23553 | Protein CBG23553. (240 aa) |
| | sao-1 | Protein CBG11416. (253 aa) |
| | pdi-6 | Protein CBR-TAG-320; Belongs to the protein disulfide isomerase family. (437 aa) |
| | Cbr-rgs-4 | Protein CBR-RGS-4. (191 aa) |
| | lin-52 | Protein CBR-LIN-52. (162 aa) |
| | rgs-1 | Protein CBR-RGS-1. (215 aa) |
| | CBG09342 | Protein CBG09342; Belongs to the mitochondrial carrier (TC 2.A.29) family. (284 aa) |
| | ppm-1.a | Protein CBR-PPM-1. (468 aa) |
| | acy-3 | Protein CBR-ACY-3. (1243 aa) |
| | daf-4 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (742 aa) |
| | rgs-5 | Protein CBR-RGS-5. (486 aa) |
| | CBG09063 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (455 aa) |
| | ins-1 | Protein CBR-INS-1. (108 aa) |
| | apr-1 | APC-related protein 1; Has a role in endoderm cell specification and pharyngeal development. Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis. Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation. During larval development, apr-1 is required for expression of lin-39 in P3-8.p. Shown to negatively regulate Wnt signaling in vulval precursor cells. Has a role in cell division by establishing the polarity of the mother cel [...] (1171 aa) |
| | sli-1 | Protein CBR-SLI-1. (546 aa) |
| | arr-1 | Protein CBR-ARR-1. (450 aa) |
| | gsk-3 | Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (359 aa) |
| | gale-1 | UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (369 aa) |
| | nlg-1 | Protein CBR-NLG-1. (800 aa) |
| | bra-1 | Protein CBG07410. (182 aa) |
| | tap-1 | Protein CBR-TAP-1. (389 aa) |
| | CBG07560 | Protein CBG07560; Belongs to the protein kinase superfamily. (367 aa) |
| | CBG07586 | Protein CBG07586. (211 aa) |
| | CBG07587 | Protein CBG07587. (232 aa) |
| | pag-3 | Protein CBR-PAG-3. (387 aa) |
| | lron-3 | Protein CBR-LRON-3. (377 aa) |
| | tax-4 | Protein CBR-TAX-4. (726 aa) |
| | pat-2 | Integrin alpha pat-2; Required for muscle development probably through the regulation of the actin-myosin cytoskeleton. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably through lamins such as epi-1, lam-2 and unc-52. Required for distal tip cell migration and dorsal pathfinding. Required for egg-laying. May play a role in cell motility and cell-cell interactions. (1224 aa) |
| | pde-2 | Phosphodiesterase. (959 aa) |
| | frm-10 | Protein CBR-FRM-10. (533 aa) |
| | CBG06678 | Protein CBG06678. (377 aa) |
| | CBG06638 | Protein CBG06638. (771 aa) |
| | lip-1 | Protein CBR-LIP-1. (376 aa) |
| | CBG05749 | Protein CBG05749. (407 aa) |
| | CBG05751 | Protein CBG05751. (360 aa) |
| | hecd-1 | Protein CBR-HECD-1. (2727 aa) |
| | nprl-2 | Protein CBG05911. (756 aa) |
| | bcc-1 | Protein CBR-BCC-1. (571 aa) |
| | sfrp-1 | Protein CBR-SFRP-1. (290 aa) |
| | lon-1 | Protein CBR-LON-1; Belongs to the CRISP family. (310 aa) |
| | mig-1 | Protein CBR-MIG-1; Belongs to the G-protein coupled receptor Fz/Smo family. (518 aa) |
| | cng-1 | Protein CBR-CNG-1. (682 aa) |
| | polh-1 | Protein CBR-POLH-1. (594 aa) |
| | ins-18 | Protein CBR-INS-18. (101 aa) |
| | che-3 | Protein CBR-CHE-3. (4802 aa) |
| | CBG11861 | Protein CBG11861. (291 aa) |
| | CBG11949 | Protein CBG11949; Belongs to the ubiquitin-conjugating enzyme family. (171 aa) |
| | CBG12386 | Protein CBG12386. (2855 aa) |
| | CBG12398 | Protein CBG12398. (316 aa) |
| | tax-2 | Protein CBR-TAX-2. (810 aa) |
| | gei-17 | Protein CBR-GEI-17. (675 aa) |
| | pde-5 | Phosphodiesterase. (715 aa) |
| | lron-8 | Protein CBR-LRON-8. (336 aa) |
| | axl-1 | Axin-like protein 1; Works in parallel with pry-1 in negatively regulating bar-1 signaling in vulval precursor cells and Q neuroblasts. Shown to have a role in excretory cell development (By similarity). (395 aa) |
| | frk-1 | Tyrosine-protein kinase. (389 aa) |
| | let-607 | Protein CBR-LET-607. (686 aa) |
| | spg-20 | Protein CBG12661. (476 aa) |
| | CBG12734 | Protein CBG12734. (212 aa) |
| | ned-8 | Protein CBR-NED-8. (76 aa) |
| | pde-4 | Phosphodiesterase. (785 aa) |
| | puf-8 | Protein CBR-PUF-8. (535 aa) |
| | plr-1 | Protein CBG13282. (470 aa) |
| | ark-1 | Protein CBR-ARK-1. (1032 aa) |
| | che-2 | Protein CBR-CHE-2. (761 aa) |
| | CBG13919 | Protein CBG13919. (648 aa) |
| | CBG13918 | Protein CBG13918. (107 aa) |
| | CBG13879 | Protein CBG13879. (72 aa) |
