(35 nodes) Positive regulation of neuron projection development network (Caenorhabditis briggsae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	faah-1	Protein CBR-FAAH-1. (572 aa)
	tpa-1	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
	dbn-1	Protein CBG18266. (672 aa)
	unc-5	Protein CBR-UNC-5. (922 aa)
	egl-30	Protein CBR-EGL-30. (388 aa)
	aex-3	Protein CBR-AEX-3. (1500 aa)
	mlk-1	Protein CBR-MLK-1. (1091 aa)
	ida-1	Protein CBR-IDA-1. (722 aa)
	nid-1	Protein CBR-NID-1. (1590 aa)
	sqv-3	Protein CBR-SQV-3. (285 aa)
	emb-9	Protein CBR-EMB-9. (1759 aa)
	svh-2	Protein CBG10839; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1120 aa)
	unc-6	Protein CBR-UNC-6. (621 aa)
	unc-104	Protein CBR-UNC-104; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1699 aa)
	mak-2	Protein CBR-MAK-2; Belongs to the protein kinase superfamily. (366 aa)
	ddr-2	Protein CBR-DDR-2. (898 aa)
	lin-18	Protein CBR-LIN-18. (599 aa)
	ddr-1	Protein CBR-DDR-1. (821 aa)
	tns-1	Protein CBR-TAG-163. (938 aa)
	kpc-1	Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
	twf-2	Protein CBG16364. (376 aa)
	cab-1	Protein CBR-CAB-1. (420 aa)
	mnm-2	Protein CBR-MNM-2. (250 aa)
	mek-1	Protein CBR-MEK-1. (463 aa)
	cwn-1	Protein CBR-CWN-1. (372 aa)
	egl-8	Phosphoinositide phospholipase C. (1528 aa)
	shc-1	Protein CBR-SHC-1. (317 aa)
	mig-1	Protein CBR-MIG-1; Belongs to the G-protein coupled receptor Fz/Smo family. (518 aa)
	mom-5	Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family. (570 aa)
	pat-3	Integrin beta; Belongs to the integrin beta chain family. (818 aa)
	unc-64	Syntaxin-1A; Plays a critical role in several secretory processes, including cuticle secretion and neurotransmitter release, and probably assists in neuronal membrane maturation or the final stages of neuronal differentiation. Essential for embryonic viability and development. Has a role in dauer formation and adult life span. Required for locomotion. Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 and upstream of innexin unc-7 and egl-4/PKG in ALA neurons, involved in the decrease in pharyngeal pumping during the quiescent s [...] (293 aa)
	egl-20	Protein CBR-EGL-20. (398 aa)
	ndnf-1	Protein CBR-NDNF-1. (536 aa)
	rab-3	Protein CBR-RAB-3. (219 aa)
	pmk-3	Mitogen-activated protein kinase. (466 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aex-3	rab-3	A8X5V3	A8WU73	Protein CBR-AEX-3.	Protein CBR-RAB-3.	0.887
cab-1	sqv-3	A8XNV8	A8XA24	Protein CBR-CAB-1.	Protein CBR-SQV-3.	0.632
cwn-1	egl-20	A8X402	A8WV58	Protein CBR-CWN-1.	Protein CBR-EGL-20.	0.932
cwn-1	lin-18	A8X402	A8XJR3	Protein CBR-CWN-1.	Protein CBR-LIN-18.	0.945
cwn-1	mig-1	A8X402	A8WZ70	Protein CBR-CWN-1.	Protein CBR-MIG-1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.993
cwn-1	mom-5	A8X402	A8WWU4	Protein CBR-CWN-1.	Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.995
cwn-1	unc-6	A8X402	A8XCA2	Protein CBR-CWN-1.	Protein CBR-UNC-6.	0.459
dbn-1	twf-2	A8XSA4	A8XNL5	Protein CBG18266.	Protein CBG16364.	0.574
ddr-1	emb-9	A8XKG5	A8XAF1	Protein CBR-DDR-1.	Protein CBR-EMB-9.	0.643
ddr-1	nid-1	A8XKG5	A8X8Y5	Protein CBR-DDR-1.	Protein CBR-NID-1.	0.530
ddr-1	svh-2	A8XKG5	A8XC40	Protein CBR-DDR-1.	Protein CBG10839; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.641
ddr-2	emb-9	A8XJG8	A8XAF1	Protein CBR-DDR-2.	Protein CBR-EMB-9.	0.643
ddr-2	nid-1	A8XJG8	A8X8Y5	Protein CBR-DDR-2.	Protein CBR-NID-1.	0.599
ddr-2	shc-1	A8XJG8	A8WZ72	Protein CBR-DDR-2.	Protein CBR-SHC-1.	0.449
egl-20	cwn-1	A8WV58	A8X402	Protein CBR-EGL-20.	Protein CBR-CWN-1.	0.932
egl-20	lin-18	A8WV58	A8XJR3	Protein CBR-EGL-20.	Protein CBR-LIN-18.	0.944
egl-20	mig-1	A8WV58	A8WZ70	Protein CBR-EGL-20.	Protein CBR-MIG-1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.991
egl-20	mom-5	A8WV58	A8WWU4	Protein CBR-EGL-20.	Protein CBR-MOM-5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.992
egl-20	unc-5	A8WV58	A8XWR5	Protein CBR-EGL-20.	Protein CBR-UNC-5.	0.633
egl-20	unc-6	A8WV58	A8XCA2	Protein CBR-EGL-20.	Protein CBR-UNC-6.	0.643