(30 nodes) Phospholipid transport network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	tat-1	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1218 aa)
	CBG20406	Protein CBG20406. (962 aa)
	CBG25585	Protein CBG25585. (211 aa)
	ced-8	Cell death abnormality protein 8; Acts downstream of ced-9 and caspase ced-3 to promote phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Regulates apoptosis kinetics during embryonic development. Not required for engulfment of germ cell corpses. (460 aa)
	CBG22145	Protein CBG22145. (273 aa)
	ttr-52	Protein CBR-TTR-52. (136 aa)
	Cbr-tag-175	Protein CBR-TAG-175. (275 aa)
	CBG18974	Protein CBG18974. (495 aa)
	tat-3	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1402 aa)
	tat-5	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1072 aa)
	CBG16211	Protein CBG16211; Belongs to the CDC50/LEM3 family. (350 aa)
	CBG15800	Protein CBG15800. (209 aa)
	scrm-1	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (264 aa)
	dsc-4	Protein CBR-DSC-4. (914 aa)
	tat-2	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1526 aa)
	ced-7	Protein CBR-CED-7. (1784 aa)
	CBG09844	Protein CBG09844. (270 aa)
	pitp-1	Protein CBR-PITP-1. (1043 aa)
	CBG08000	Protein CBG08000. (625 aa)
	Cbr-scrm-6	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (284 aa)
	obr-3	Protein CBR-OBR-3. (797 aa)
	CBG05887	Protein CBG05887. (174 aa)
	CBG06218	Protein CBG06218. (216 aa)
	num-1	Protein CBR-NUM-1. (636 aa)
	CBG04045	Protein CBG04045. (159 aa)
	CBG04043	Protein CBG04043. (115 aa)
	Cbr-tat-4.2	Protein CBR-TAT-4.2. (319 aa)
	tat-4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1235 aa)
	mdmh-35	Protein CBG03307. (98 aa)
	chat-1	Protein CBR-CHAT-1; Belongs to the CDC50/LEM3 family. (350 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG04043	CBG04045	A8WW26	A8WW28	Protein CBG04043.	Protein CBG04045.	0.464
CBG04043	tat-5	A8WW26	A8XQ33	Protein CBG04043.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.439
CBG04045	CBG04043	A8WW28	A8WW26	Protein CBG04045.	Protein CBG04043.	0.464
CBG04045	tat-5	A8WW28	A8XQ33	Protein CBG04045.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.439
CBG15800	CBG25585	A8XMZ7	B6IF72	Protein CBG15800.	Protein CBG25585.	0.857
CBG15800	mdmh-35	A8XMZ7	A8WSC0	Protein CBG15800.	Protein CBG03307.	0.984
CBG16211	Cbr-tat-4.2	A8XNV9	A8WTY5	Protein CBG16211; Belongs to the CDC50/LEM3 family.	Protein CBR-TAT-4.2.	0.618
CBG16211	tat-1	A8XNV9	A8XDT2	Protein CBG16211; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.682
CBG16211	tat-2	A8XNV9	A8XDR6	Protein CBG16211; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.682
CBG16211	tat-3	A8XNV9	A8XSF4	Protein CBG16211; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.682
CBG16211	tat-4	A8XNV9	A8WTY4	Protein CBG16211; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.682
CBG16211	tat-5	A8XNV9	A8XQ33	Protein CBG16211; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.677
CBG25585	CBG15800	B6IF72	A8XMZ7	Protein CBG25585.	Protein CBG15800.	0.857
CBG25585	mdmh-35	B6IF72	A8WSC0	Protein CBG25585.	Protein CBG03307.	0.996
Cbr-scrm-6	ced-8	A8X5F7	A8Y2U2	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.	Cell death abnormality protein 8; Acts downstream of ced-9 and caspase ced-3 to promote phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Regulates apoptosis kinetics during embryonic development. Not required for engulfment of germ cell corpses.	0.497
Cbr-tat-4.2	CBG16211	A8WTY5	A8XNV9	Protein CBR-TAT-4.2.	Protein CBG16211; Belongs to the CDC50/LEM3 family.	0.618
Cbr-tat-4.2	chat-1	A8WTY5	A8WR28	Protein CBR-TAT-4.2.	Protein CBR-CHAT-1; Belongs to the CDC50/LEM3 family.	0.618
Cbr-tat-4.2	tat-5	A8WTY5	A8XQ33	Protein CBR-TAT-4.2.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.522
ced-7	ced-8	A8XA90	A8Y2U2	Protein CBR-CED-7.	Cell death abnormality protein 8; Acts downstream of ced-9 and caspase ced-3 to promote phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Regulates apoptosis kinetics during embryonic development. Not required for engulfment of germ cell corpses.	0.802
ced-7	scrm-1	A8XA90	A8XMZ4	Protein CBR-CED-7.	Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.	0.628