STRINGSTRING
kpc-1 kpc-1 CBG17784 CBG17784 CBG17781 CBG17781 nep-6 nep-6 nep-11 nep-11 spcs-1 spcs-1 vps-41 vps-41 spcs-2 spcs-2 ced-4 ced-4 spcs-3 spcs-3 CBG24895 CBG24895 CBG15389 CBG15389 spe-4 spe-4 aph-1 aph-1 mig-17 mig-17 CBG23516 CBG23516 lonp-2 lonp-2 nep-15 nep-15 CBG22515 CBG22515 mppa-1 mppa-1 imp-3 imp-3 grd-1 grd-1 myrf-2 myrf-2 CBG16820 CBG16820 cpd-2 cpd-2 fce-2.3 fce-2.3 CBG15395 CBG15395 rom-5 rom-5 spg-7 spg-7 hog-1 hog-1 wrt-6 wrt-6 wrt-2 wrt-2 map-2 map-2 immp-1 immp-1 wrt-1 wrt-1 CBG12981 CBG12981 CBG12595 CBG12595 bli-4 bli-4 pqn-59.1 pqn-59.1 mppb-1 mppb-1 tra-3 tra-3 aph-2 aph-2 nep-17 nep-17 nep-26 nep-26 aex-5 aex-5 atg-4.1 atg-4.1 nep-2 nep-2 CBG24462 CBG24462 psd-1 psd-1 map-1 map-1 egl-21 egl-21 egl-3 egl-3 CBG10913 CBG10913 CBG10917 CBG10917 CBG10918 CBG10918 hop-1 hop-1 cpd-1 cpd-1 CBG12511 CBG12511 CBG08322 CBG08322 CBG08321 CBG08321 sel-12 sel-12 wrt-4 wrt-4 nep-16 nep-16 imp-2 imp-2 CBG05330 CBG05330 CBG04988 CBG04988 nep-21 nep-21 CBG04432 CBG04432 CBG04354 CBG04354 CBG04353 CBG04353 CBG04350 CBG04350 nep-18 nep-18 fce-1 fce-1 sec-11 sec-11 nep-5 nep-5 nep-25 nep-25 nep-1 nep-1 myrf-1 myrf-1 CBG01792 CBG01792 ced-3 ced-3 CBG00683 CBG00683 nep-22 nep-22 CBG24463 CBG24463 fce-2.2 fce-2.2 ymel-1 ymel-1 spe-39 spe-39 CBG19473 CBG19473
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kpc-1Protein CBR-KPC-1; Belongs to the peptidase S8 family. (686 aa)
CBG17784Protein CBG17784. (657 aa)
CBG17781Protein CBG17781. (717 aa)
nep-6Protein CBG17780. (757 aa)
nep-11Protein CBG17774. (883 aa)
spcs-1Probable signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (113 aa)
vps-41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane [...] (898 aa)
spcs-2Probable signal peptidase complex subunit 2; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (180 aa)
ced-4Cell death protein 4; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to induce caspase ced-3 autoproteolytic cleavage and activation. Also forms an holoenzyme with processed ced-3 enhancing ced-3 activity. Component of the egl-1, ced-9, ced-4 and ced- 3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During [...] (569 aa)
spcs-3Probable signal peptidase complex subunit 3; Component of the microsomal signal peptidase complex which removes signal peptides and other N-terminal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (180 aa)
CBG24895Protein CBG24895. (473 aa)
CBG15389Protein CBG15389. (1142 aa)
spe-4Protein CBR-SPE-4. (483 aa)
aph-1Protein CBR-APH-1. (330 aa)
mig-17Protein CBR-MIG-17. (533 aa)
CBG23516Protein CBG23516. (463 aa)
lonp-2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. (773 aa)
nep-15Protein CBG22755. (424 aa)
CBG22515Protein CBG22515; Belongs to the peptidase C14A family. (417 aa)
mppa-1Protein CBR-MPPA-1. (552 aa)
imp-3Protein CBR-IMP-3. (516 aa)
grd-1Protein CBR-GRD-1. (1210 aa)
myrf-2Protein CBG17173. (863 aa)
CBG16820Protein CBG16820. (749 aa)
cpd-2Protein CBG16407. (492 aa)
fce-2.3Protein CBG17836. (260 aa)
CBG15395Protein CBG15395. (430 aa)
rom-5Protein CBR-ROM-5. (336 aa)
spg-7Protein CBR-SPG-7. (814 aa)
hog-1Protein CBR-HOG-1. (195 aa)
wrt-6Protein CBR-WRT-6. (628 aa)
wrt-2Protein CBR-WRT-2. (464 aa)
map-2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (441 aa)
immp-1Protein CBR-IMMP-1. (156 aa)
wrt-1Protein CBR-WRT-1. (490 aa)
CBG12981Protein CBG12981. (268 aa)
CBG12595Protein CBG12595. (87 aa)
bli-4Protein CBR-BLI-4; Belongs to the peptidase S8 family. (730 aa)
pqn-59.1Protein CBR-PQN-59.1. (1239 aa)
mppb-1Protein CBR-MPPB-1; Belongs to the peptidase M16 family. (459 aa)
tra-3Protein CBR-TRA-3; Belongs to the peptidase C2 family. (646 aa)
aph-2Protein CBR-APH-2. (721 aa)
nep-17Protein CBG20766. (1613 aa)
nep-26Protein CBG20236. (856 aa)
aex-5Protein CBR-AEX-5. (541 aa)
atg-4.1Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (461 aa)
nep-2Protein CBR-NEP-2. (738 aa)
CBG24462Protein CBG24462. (229 aa)
psd-1Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (348 aa)
map-1Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (372 aa)
egl-21Protein CBR-EGL-21. (473 aa)
egl-3Protein CBR-EGL-3; Belongs to the peptidase S8 family. (662 aa)
CBG10913Protein CBG10913. (501 aa)
CBG10917Protein CBG10917. (504 aa)
CBG10918Protein CBG10918. (430 aa)
hop-1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
cpd-1Protein CBG12487. (1035 aa)
CBG12511Protein CBG12511. (184 aa)
CBG08322Protein CBG08322. (275 aa)
CBG08321Protein CBG08321. (139 aa)
sel-12Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
wrt-4Protein CBR-WRT-4. (555 aa)
nep-16Protein CBG05928. (983 aa)
imp-2Protein CBR-IMP-2. (465 aa)
CBG05330Protein CBG05330. (91 aa)
CBG04988Protein CBG04988. (595 aa)
nep-21Protein CBG04739. (778 aa)
CBG04432Protein CBG04432. (1630 aa)
CBG04354Protein CBG04354. (286 aa)
CBG04353Protein CBG04353. (760 aa)
CBG04350Protein CBG04350. (272 aa)
nep-18Protein CBG04334. (1406 aa)
fce-1CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (442 aa)
sec-11Signal peptidase complex catalytic subunit SEC11. (183 aa)
nep-5Protein CBG02411. (669 aa)
nep-25Protein CBG02520. (402 aa)
nep-1Protein CBR-NEP-1. (754 aa)
myrf-1Protein CBR-PQN-47. (925 aa)
CBG01792Protein CBG01792. (705 aa)
ced-3Protein CBR-CED-3; Belongs to the peptidase C14A family. (508 aa)
CBG00683Protein CBG00683. (1182 aa)
nep-22Protein CBG00200. (859 aa)
CBG24463Protein CBG24463. (242 aa)
fce-2.2Protein CBR-FCE-2. (225 aa)
ymel-1Protein CBR-YMEL-1; Belongs to the AAA ATPase family. (670 aa)
spe-39Protein CBR-SPE-39. (523 aa)
CBG19473Protein CBG19473. (96 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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