STRINGSTRING
air-2 air-2 hasp-1 hasp-1 CBG02222 CBG02222 vrk-1 vrk-1 CBG12411 CBG12411 CBG17207 CBG17207 CBG17438 CBG17438 CBG22011 CBG22011 air-1 air-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
air-2Aurora/IPL1-related protein kinase 2; Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates tlk-1 and zen-4 (By similarity). (302 aa)
hasp-1Protein CBG01851. (918 aa)
CBG02222Protein CBG02222. (436 aa)
vrk-1Serine/threonine-protein kinase VRK1; Serine/threonine kinase that phosphorylates baf-1, thus regulating the association of baf-1 with chromatin and nuclear membrane proteins during nuclear envelope formation. May act through the egl-17 signaling pathway. Essential in hermaphrodites for formation of the vulva, uterus, and uterine seam cells and for development and maintenance of the somatic gonad and thus the germ line. Acts to prevent cep-1 from triggering an inappropriate cell cycle arrest, thereby promoting germ cell proliferation. Regulates anchor cell polarity and the timing of an [...] (559 aa)
CBG12411Protein CBG12411. (518 aa)
CBG17207Protein CBG17207. (455 aa)
CBG17438Protein CBG17438. (107 aa)
CBG22011Protein CBG22011. (228 aa)
air-1Protein CBR-AIR-1.1; Belongs to the protein kinase superfamily. (327 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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