(19 nodes) Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	alh-10	Protein CBR-ALH-10; Belongs to the aldehyde dehydrogenase family. (506 aa)
	let-767	Very-long-chain 3-oxooacyl-coA reductase let-767; Required for branched chain fatty acid synthesis. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. Very long-chain fatty acids (VLCFAs) serve as precursors for ceramide and sphingolipids. May also be required for sterol hormone production (By similarity). (316 aa)
	gpd-3.1	Glyceraldehyde-3-phosphate dehydrogenase 3.1; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
	gpd-3.2	Glyceraldehyde-3-phosphate dehydrogenase 2; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
	CBG25152	Protein CBG25152. (218 aa)
	alh-1	Protein CBR-ALH-1; Belongs to the aldehyde dehydrogenase family. (511 aa)
	alh-7	Protein CBR-ALH-7; Belongs to the aldehyde dehydrogenase family. (499 aa)
	alh-4	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (505 aa)
	alh-11	Protein CBR-ALH-11; Belongs to the aldehyde dehydrogenase family. (684 aa)
	CBG12246	Protein CBG12246. (352 aa)
	alh-12	Protein CBR-ALH-12. (499 aa)
	alh-9	Protein CBR-ALH-9; Belongs to the aldehyde dehydrogenase family. (508 aa)
	alh-6	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
	alh-3	10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
	alh-8	Protein CBR-ALH-8. (523 aa)
	fard-1	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (555 aa)
	Cbr-gpd-1	Glyceraldehyde-3-phosphate dehydrogenase. (341 aa)
	CBG00820	Glyceraldehyde-3-phosphate dehydrogenase. (341 aa)
	alh-13	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (802 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00820	alh-13	A8WNX0	A8WM90	Glyceraldehyde-3-phosphate dehydrogenase.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.679
CBG12246	alh-13	A8XF31	A8WM90	Protein CBG12246.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.780
CBG25152	alh-13	B0K0B0	A8WM90	Protein CBG25152.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.491
Cbr-gpd-1	alh-13	A8WQL1	A8WM90	Glyceraldehyde-3-phosphate dehydrogenase.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.679
alh-1	alh-13	A8Y3G4	A8WM90	Protein CBR-ALH-1; Belongs to the aldehyde dehydrogenase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.780
alh-1	alh-4	A8Y3G4	A8XUD6	Protein CBR-ALH-1; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.924
alh-1	alh-6	A8Y3G4	A8X3N9	Protein CBR-ALH-1; Belongs to the aldehyde dehydrogenase family.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.803
alh-1	alh-8	A8Y3G4	A8WSQ3	Protein CBR-ALH-1; Belongs to the aldehyde dehydrogenase family.	Protein CBR-ALH-8.	0.936
alh-10	alh-13	A8XBZ5	A8WM90	Protein CBR-ALH-10; Belongs to the aldehyde dehydrogenase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.780
alh-11	alh-12	A8XLN9	A8X897	Protein CBR-ALH-11; Belongs to the aldehyde dehydrogenase family.	Protein CBR-ALH-12.	0.903
alh-11	alh-13	A8XLN9	A8WM90	Protein CBR-ALH-11; Belongs to the aldehyde dehydrogenase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.780
alh-11	alh-6	A8XLN9	A8X3N9	Protein CBR-ALH-11; Belongs to the aldehyde dehydrogenase family.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.803
alh-11	alh-8	A8XLN9	A8WSQ3	Protein CBR-ALH-11; Belongs to the aldehyde dehydrogenase family.	Protein CBR-ALH-8.	0.937
alh-12	alh-11	A8X897	A8XLN9	Protein CBR-ALH-12.	Protein CBR-ALH-11; Belongs to the aldehyde dehydrogenase family.	0.903
alh-12	alh-13	A8X897	A8WM90	Protein CBR-ALH-12.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.780
alh-12	alh-6	A8X897	A8X3N9	Protein CBR-ALH-12.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.803
alh-12	alh-8	A8X897	A8WSQ3	Protein CBR-ALH-12.	Protein CBR-ALH-8.	0.938
alh-13	CBG00820	A8WM90	A8WNX0	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.679
alh-13	CBG12246	A8WM90	A8XF31	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Protein CBG12246.	0.780
alh-13	CBG25152	A8WM90	B0K0B0	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Protein CBG25152.	0.491