STRINGSTRING
odc-1 odc-1 spl-2 spl-2 CBG19472 CBG19472 CBG19453 CBG19453 gcy-21 gcy-21 gcy-35 gcy-35 CBG20392 CBG20392 pgal-1 pgal-1 CBG20661 CBG20661 CBG20808 CBG20808 gcy-29 gcy-29 CBG20870 CBG20870 bca-1 bca-1 CBG14840 CBG14840 CBG14085 CBG14085 CBG14065 CBG14065 gcy-37 gcy-37 CBG13912 CBG13912 spl-3 spl-3 CBG13950 CBG13950 tsen-34 tsen-34 CBG13739 CBG13739 CBG13687 CBG13687 maoc-1 maoc-1 cah-2 cah-2 ech-1.2 ech-1.2 CBG12517 CBG12517 nth-1 nth-1 CBG12088 CBG12088 CBG12007 CBG12007 cah-6 cah-6 acsd-1 acsd-1 gcy-7 gcy-7 CBG11175 CBG11175 spl-1 spl-1 CBG10474 CBG10474 CBG10472 CBG10472 ech-6 ech-6 CBG09979 CBG09979 acy-2 acy-2 CBG09341 CBG09341 acy-4 acy-4 Cbr-gcy-6 Cbr-gcy-6 acy-3 acy-3 fum-1 fum-1 bas-1 bas-1 aldo-2 aldo-2 ech-7 ech-7 CBG08368 CBG08368 CBG07423 CBG07423 CBG07424 CBG07424 odr-1 odr-1 cah-4 cah-4 mocs-1 mocs-1 gcy-36 gcy-36 CBG06975 CBG06975 djr-1.2 djr-1.2 djr-1.1 djr-1.1 CBG07184 CBG07184 CBG07192 CBG07192 CBG06820 CBG06820 gcy-34 gcy-34 adsl-1 adsl-1 CBG26633 CBG26633 CBG14864 CBG14864 gcy-28 gcy-28 pamn-1 pamn-1 CBG15091 CBG15091 CBG15092 CBG15092 aldo-1 aldo-1 unc-25 unc-25 pck-3 pck-3 CBG06697 CBG06697 CBG06637 CBG06637 CBG06559 CBG06559 icl-1 icl-1 hdl-1 hdl-1 ech-2 ech-2 CBG06215 CBG06215 gcy-22 gcy-22 gcy-32 gcy-32 CBG04553 CBG04553 gcy-14 gcy-14 CBG04453 CBG04453 endu-1 endu-1 pcbd-1 pcbd-1 gcy-17 gcy-17 pacs-1 pacs-1 CBG03656 CBG03656 nit-1 nit-1 CBG03380 CBG03380 gcy-12 gcy-12 CBG02379 CBG02379 cchl-1 cchl-1 enol-1 enol-1 gcy-31 gcy-31 CBG01970 CBG01970 CBG01968 CBG01968 cbs-1 cbs-1 gcy-23 gcy-23 gcy-5 gcy-5 gcy-4 gcy-4 Cbr-gcy-1 Cbr-gcy-1 cysl-2 cysl-2 CBG00666 CBG00666 tdc-1 tdc-1 bca-2 bca-2 gcy-25 gcy-25 pck-1 pck-1 CBG24871 CBG24871 cth-2 cth-2 umps-1 umps-1 CBG24506 CBG24506 gcy-18 gcy-18 psd-1 psd-1 ech-5 ech-5 CBG23859 CBG23859 CBG23757 CBG23757 tpi-1 tpi-1 CBG21104 CBG21104 CBG21102 CBG21102 CBG21737 CBG21737 cbl-1 cbl-1 CBG22170 CBG22170 ptps-1 ptps-1 cah-1 cah-1 aco-2 aco-2 gcy-13 gcy-13 gcy-33 gcy-33 daf-11 daf-11 cah-5 cah-5 CBG25458 CBG25458 CBG27484 CBG27484 CBG25194 CBG25194 CBG27447 CBG27447 CBG27462 CBG27462 pck-2 pck-2 CBG10371 CBG10371 fecl-1 fecl-1 CBG23831 CBG23831 CBG16084 CBG16084 gcy-11 gcy-11 cah-3 cah-3 gcy-19 gcy-19 aco-1 aco-1 gcy-9 gcy-9 haly-1 haly-1 gcy-8 gcy-8 CBG17652 CBG17652 CBG17874 CBG17874 rnst-2 rnst-2 CBG17907 CBG17907 hdl-2 hdl-2 acy-1 acy-1 mlcd-1 mlcd-1 sqv-1 sqv-1 eppl-1 eppl-1 smd-1 smd-1 hpo-8 hpo-8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
odc-1Protein CBR-ODC-1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (423 aa)
spl-2Protein CBR-TAG-38. (543 aa)
CBG19472Protein CBG19472. (216 aa)
CBG19453Protein CBG19453. (621 aa)
gcy-21Guanylate cyclase. (1193 aa)
gcy-35Protein CBR-GCY-35. (451 aa)
CBG20392Protein CBG20392; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (273 aa)
pgal-1Protein CBR-PGAL-1. (360 aa)
CBG20661Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (372 aa)
CBG20808Protein CBG20808. (467 aa)
gcy-29Guanylate cyclase. (1072 aa)
CBG20870Protein CBG20870. (388 aa)
bca-1Beta carbonic anhydrase 1; Reversible hydration of carbon dioxide. (270 aa)
CBG14840Protein CBG14840. (242 aa)
CBG14085Protein CBG14085. (342 aa)
CBG14065Protein CBG14065. (610 aa)
gcy-37Protein CBR-GCY-37; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (993 aa)
CBG13912Protein CBG13912. (271 aa)
spl-3Protein CBG13938. (362 aa)
CBG13950Protein CBG13950. (137 aa)
tsen-34Protein CBG13974. (220 aa)
CBG13739Protein CBG13739. (305 aa)
CBG13687Protein CBG13687. (670 aa)
maoc-1Protein CBR-MAOC-1. (298 aa)
cah-2Protein CBR-CAH-2; Belongs to the alpha-carbonic anhydrase family. (337 aa)
ech-1.2Protein CBG12562. (755 aa)
CBG12517Protein CBG12517. (325 aa)
nth-1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (289 aa)
CBG12088Protein CBG12088. (226 aa)
CBG12007Protein CBG12007; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa)
cah-6Protein CBR-CAH-6; Belongs to the alpha-carbonic anhydrase family. (319 aa)
acsd-12-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (355 aa)
gcy-7Guanylate cyclase. (1124 aa)
CBG11175Protein CBG11175. (184 aa)
spl-1Protein CBR-SPL-1. (552 aa)
CBG10474Guanylate cyclase. (782 aa)
CBG10472Protein CBG10472. (597 aa)
ech-6Protein CBR-ECH-6; Belongs to the enoyl-CoA hydratase/isomerase family. (288 aa)
CBG09979Protein CBG09979; Belongs to the enoyl-CoA hydratase/isomerase family. (286 aa)
acy-2Protein CBR-ACY-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1132 aa)
CBG09341Protein CBG09341. (129 aa)
acy-4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1000 aa)
Cbr-gcy-6Guanylate cyclase. (1104 aa)
acy-3Protein CBR-ACY-3. (1243 aa)
fum-1Protein CBR-FUM-1. (491 aa)
bas-1Protein CBR-BAS-1. (514 aa)
aldo-2Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (366 aa)
ech-7Protein CBR-ECH-7; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
CBG08368Protein CBG08368. (253 aa)
CBG07423Protein CBG07423. (511 aa)
CBG07424Protein CBG07424. (395 aa)
odr-1Protein CBR-ODR-1. (609 aa)
cah-4Protein CBR-CAH-4; Belongs to the alpha-carbonic anhydrase family. (279 aa)
mocs-1Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (707 aa)
gcy-36Protein CBR-GCY-36; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (759 aa)
CBG06975Protein CBG06975. (423 aa)
djr-1.2Protein CBR-DJR-1.2. (192 aa)
djr-1.1Protein CBR-DJR-1.1. (187 aa)
CBG07184Protein CBG07184. (194 aa)
CBG07192Protein CBG07192. (187 aa)
CBG06820ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (307 aa)
gcy-34Protein CBR-GCY-34; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (686 aa)
adsl-1Adenylosuccinate lyase; Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (478 aa)
CBG26633Protein CBG26633. (35 aa)
CBG14864Protein CBG14864. (305 aa)
gcy-28Guanylate cyclase. (1264 aa)
pamn-1Protein CBR-PAMN-1. (727 aa)
CBG15091Protein CBG15091. (267 aa)
CBG15092Protein CBG15092. (226 aa)
aldo-1Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (365 aa)
unc-25Protein CBR-UNC-25. (510 aa)
pck-3Protein CBG06707. (584 aa)
CBG06697Protein CBG06697. (241 aa)
CBG06637Protein CBG06637. (568 aa)
CBG06559Guanylate cyclase. (1291 aa)
icl-1Malate synthase; Belongs to the malate synthase family. (975 aa)
hdl-1Protein CBR-HDL-1. (933 aa)
ech-2Protein CBR-ECH-2. (283 aa)
CBG06215Protein CBG06215. (458 aa)
gcy-22Guanylate cyclase. (1076 aa)
gcy-32Protein CBG04937; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (683 aa)
CBG04553Protein CBG04553. (1075 aa)
gcy-14Guanylate cyclase. (1125 aa)
CBG04453Protein CBG04453. (452 aa)
endu-1Protein CBG03808. (345 aa)
pcbd-1Protein CBR-PCBD-1. (145 aa)
gcy-17Guanylate cyclase. (1095 aa)
pacs-1Protein CBG03675. (422 aa)
CBG03656Protein CBG03656. (631 aa)
nit-1Protein CBR-NIT-1. (282 aa)
CBG03380Protein CBG03380; Belongs to the TPP enzyme family. (642 aa)
gcy-12Guanylate cyclase. (1690 aa)
CBG02379Protein CBG02379. (303 aa)
cchl-1Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (281 aa)
enol-1Protein CBR-ENOL-1. (434 aa)
gcy-31Protein CBR-GCY-31; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (713 aa)
CBG01970Protein CBG01970. (116 aa)
CBG01968Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (169 aa)
cbs-1Protein CBR-CBS-2. (701 aa)
gcy-23Guanylate cyclase. (1047 aa)
gcy-5Guanylate cyclase. (1242 aa)
gcy-4Receptor-type guanylate cyclase gcy-4; Guanylate cyclase involved in the production of the second messenger cGMP. Regulates chemotaxis responses toward salt ions in ASE sensory neurons (By similarity). (1135 aa)
Cbr-gcy-1Guanylate cyclase. (957 aa)
cysl-2Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (337 aa)
CBG00666Protein CBG00666. (502 aa)
tdc-1Protein CBR-TDC-1. (707 aa)
bca-2Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (259 aa)
gcy-25Guanylate cyclase. (1066 aa)
pck-1Protein CBG00466. (648 aa)
CBG24871Protein CBG24871. (125 aa)
cth-2Protein CBG24746. (392 aa)
umps-1Protein CBR-UMPS-1. (498 aa)
CBG24506Protein CBG24506. (202 aa)
gcy-18Guanylate cyclase. (1145 aa)
psd-1Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (348 aa)
ech-5Protein CBR-ECH-5; Belongs to the enoyl-CoA hydratase/isomerase family. (613 aa)
CBG23859Protein CBG23859. (653 aa)
CBG23757Protein CBG23757. (226 aa)
tpi-1Triosephosphate isomerase. (247 aa)
CBG21104Protein CBG21104. (144 aa)
CBG21102Protein CBG21102. (117 aa)
CBG21737GDP-mannose 4,6 dehydratase 1; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-2, bre-3 and bre-4. Has a role in determining brood size (By similarity); Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. (377 aa)
cbl-1Protein CBG22025. (414 aa)
CBG22170Protein CBG22170. (318 aa)
ptps-1Protein CBR-PTPS-1. (132 aa)
cah-1Protein CBR-CAH-1; Belongs to the alpha-carbonic anhydrase family. (310 aa)
aco-2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
gcy-13Guanylate cyclase. (1066 aa)
gcy-33Protein CBR-GCY-33; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (948 aa)
daf-11Guanylate cyclase. (1277 aa)
cah-5Protein CBR-CAH-5; Belongs to the alpha-carbonic anhydrase family. (311 aa)
CBG25458Guanylate cyclase. (1148 aa)
CBG27484Protein CBG27484. (64 aa)
CBG25194Protein CBG25194. (125 aa)
CBG27447Protein CBG27447. (111 aa)
CBG27462Protein CBG27462. (92 aa)
pck-2Protein CBG08279. (653 aa)
CBG10371Protein CBG10371; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (594 aa)
fecl-1Protein CBG20458; Belongs to the ferrochelatase family. (322 aa)
CBG23831Protein CBG23831. (223 aa)
CBG16084Protein CBG16084. (568 aa)
gcy-11Guanylate cyclase. (1097 aa)
cah-3Protein CBR-CAH-3; Belongs to the alpha-carbonic anhydrase family. (246 aa)
gcy-19Receptor-type guanylate cyclase gcy-19; Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). (1214 aa)
aco-1Protein CBR-ACO-1; Belongs to the aconitase/IPM isomerase family. (909 aa)
gcy-9Guanylate cyclase. (1156 aa)
haly-1Histidine ammonia-lyase; Belongs to the PAL/histidase family. (747 aa)
gcy-8Guanylate cyclase. (1188 aa)
CBG17652Protein CBG17652. (427 aa)
CBG17874Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (230 aa)
rnst-2Protein CBG17875; Belongs to the RNase T2 family. (243 aa)
CBG17907Protein CBG17907. (223 aa)
hdl-2Protein CBR-TAG-19. (575 aa)
acy-1Protein CBR-ACY-1. (1287 aa)
mlcd-1Protein CBG18041. (442 aa)
sqv-1Protein CBR-SQV-1. (456 aa)
eppl-1Protein CBG18478; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa)
smd-1S-adenosylmethionine decarboxylase proenzyme. (371 aa)
hpo-8Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (218 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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