STRINGSTRING
CBG23947 CBG23947 mbk-2 mbk-2 unc-51 unc-51 CBG24636 CBG24636 CBG24758 CBG24758 CBG24789 CBG24789 CBG24901 CBG24901 CBG25012 CBG25012 CBG25088 CBG25088 nekl-3 nekl-3 CBG00206 CBG00206 CBG00227 CBG00227 CBG00573 CBG00573 CBG01655 CBG01655 tpa-1 tpa-1 pmk-1 pmk-1 CBG02002 CBG02002 CBG02005 CBG02005 CBG02007 CBG02007 CBG02066 CBG02066 CBG02188 CBG02188 mak-1 mak-1 mnk-1 mnk-1 CBG03054 CBG03054 CBG02852 CBG02852 mps-1 mps-1 vrk-1 vrk-1 CBG02430 CBG02430 pink-1 pink-1 pkc-3 pkc-3 CBG03462 CBG03462 CBG03463 CBG03463 CBG04011 CBG04011 cdc-7 cdc-7 CBG04032 CBG04032 CBG03830 CBG03830 CBG04327 CBG04327 CBG04389 CBG04389 CBG05024 CBG05024 CBG05224 CBG05224 CBG05229 CBG05229 gck-3 gck-3 unc-22 unc-22 kin-4 kin-4 CBG06004 CBG06004 CBG06575 CBG06575 ikke-1 ikke-1 CBG06934 CBG06934 kin-20 kin-20 mbk-1 mbk-1 CBG07548 CBG07548 sad-1 sad-1 CBG07290 CBG07290 CBG07288 CBG07288 CBG07267 CBG07267 CBG07264 CBG07264 pdk-1 pdk-1 CBG08151 CBG08151 rskn-2 rskn-2 CBG08225 CBG08225 CBG08226 CBG08226 ttbk-5 ttbk-5 CBG08881 CBG08881 CBG08942 CBG08942 CBG09052 CBG09052 CBG09038 CBG09038 CBG08984 CBG08984 CBG09188 CBG09188 akt-1 akt-1 ttbk-7 ttbk-7 CBG09309 CBG09309 tlk-1 tlk-1 CBG10201 CBG10201 CBG10487 CBG10487 CBG10613 CBG10613 CBG10617 CBG10617 CBG10779 CBG10779 CBG10975 CBG10975 CBG11137 CBG11137 CBG11140 CBG11140 CBG11150 CBG11150 CBG11420 CBG11420 CBG11274 CBG11274 CBG11811 CBG11811 CBG11832 CBG11832 ttbk-2 ttbk-2 csnk-1 csnk-1 CBG12201 CBG12201 kin-3 kin-3 osr-1 osr-1 CBG12889 CBG12889 CBG12477 CBG12477 rskn-1 rskn-1 CBG12561 CBG12561 CBG12760 CBG12760 CBG12789 CBG12789 CBG12956 CBG12956 CBG13180 CBG13180 rsks-1 rsks-1 CBG13263 CBG13263 spe-6 spe-6 CBG13435 CBG13435 CBG13774 CBG13774 CBG13775 CBG13775 mak-2 mak-2 CBG14034 CBG14034 CBG14210 CBG14210 CBG14211 CBG14211 sax-1 sax-1 CBG14305 CBG14305 hpk-1 hpk-1 CBG14423 CBG14423 CBG14431 CBG14431 CBG14564 CBG14564 CBG14903 CBG14903 CBG14958 CBG14958 CBG15339 CBG15339 CBG15618 CBG15618 CBG15660 CBG15660 CBG16092 CBG16092 CBG16040 CBG16040 sgk-1 sgk-1 CBG16302 CBG16302 aak-2 aak-2 CBG16239 CBG16239 CBG16237 CBG16237 CBG16151 CBG16151 pkc-2 pkc-2 CBG16501 CBG16501 ttbk-4 ttbk-4 sek-1 sek-1 pkn-1 pkn-1 CBG17114 CBG17114 pek-1 pek-1 CBG18289 CBG18289 CBG18309 CBG18309 CBG18341 CBG18341 CBG18395 CBG18395 CBG17973 CBG17973 CBG17985 CBG17985 CBG18064 CBG18064 CBG18079 CBG18079 prde-1 prde-1 CBG18695 CBG18695 CBG19430 CBG19430 CBG19692 CBG19692 CBG19698 CBG19698 CBG19815 CBG19815 CBG19731 CBG19731 CBG19720 CBG19720 CBG20023 CBG20023 CBG20086 CBG20086 kin-19 kin-19 CBG20869 CBG20869 CBG20930 CBG20930 CBG20999 CBG20999 CBG21094 CBG21094 CBG21090 CBG21090 mpk-1 mpk-1 wts-1 wts-1 CBG21812 CBG21812 CBG23007 CBG23007 pkc-1 pkc-1 CBG25344 CBG25344 CBG26420 CBG26420 air-1 air-1 CBG24470 CBG24470 CBG24569 CBG24569 air-2 air-2 cdk-4 cdk-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG23947Protein CBG23947. (183 aa)
mbk-2Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2; Required for oocyte-to-zygote transition in which it phosphorylates oocyte proteins, including mei-1, oma-1, oma-2, mex-5, and mex-6, modifying their activity and/or stability following meiosis. Functions in both spindle positioning and in the posterior localization of cytoplasmic determinants, including pie-1, pos-1, and pgl-1, in early embryos. Involved in the asymmetric distribution of plk-1 at the 2-cell embryonic stage. (815 aa)
unc-51Protein CBR-UNC-51. (875 aa)
CBG24636Protein CBG24636. (770 aa)
CBG24758Protein CBG24758. (337 aa)
CBG24789Protein CBG24789. (740 aa)
CBG24901Protein CBG24901. (1154 aa)
CBG25012Protein CBG25012. (156 aa)
CBG25088Protein CBG25088. (245 aa)
nekl-3Protein CBR-NEKL-3. (224 aa)
CBG00206Protein CBG00206; Belongs to the protein kinase superfamily. (350 aa)
CBG00227Protein CBG00227. (318 aa)
CBG00573Protein CBG00573. (327 aa)
CBG01655Protein CBG01655. (295 aa)
tpa-1Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (705 aa)
pmk-1Mitogen-activated protein kinase. (377 aa)
CBG02002Protein CBG02002. (293 aa)
CBG02005Protein CBG02005. (258 aa)
CBG02007Protein CBG02007. (303 aa)
CBG02066Protein CBG02066. (194 aa)
CBG02188Protein CBG02188. (298 aa)
mak-1Protein CBG03152. (529 aa)
mnk-1Protein CBR-MNK-1. (784 aa)
CBG03054Protein CBG03054. (536 aa)
CBG02852Protein CBG02852. (515 aa)
mps-1Protein CBR-MPS-1. (308 aa)
vrk-1Serine/threonine-protein kinase VRK1; Serine/threonine kinase that phosphorylates baf-1, thus regulating the association of baf-1 with chromatin and nuclear membrane proteins during nuclear envelope formation. May act through the egl-17 signaling pathway. Essential in hermaphrodites for formation of the vulva, uterus, and uterine seam cells and for development and maintenance of the somatic gonad and thus the germ line. Acts to prevent cep-1 from triggering an inappropriate cell cycle arrest, thereby promoting germ cell proliferation. Regulates anchor cell polarity and the timing of an [...] (559 aa)
CBG02430Protein CBG02430. (324 aa)
pink-1Protein CBR-PINK-1. (1237 aa)
pkc-3Protein kinase C-like 3; Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
CBG03462Protein CBG03462. (259 aa)
CBG03463Protein CBG03463. (235 aa)
CBG04011Protein CBG04011. (320 aa)
cdc-7Protein CBR-CDC-7; Belongs to the protein kinase superfamily. (409 aa)
CBG04032Protein CBG04032. (381 aa)
CBG03830Protein CBG03830. (415 aa)
CBG04327Protein CBG04327; Belongs to the protein kinase superfamily. (354 aa)
CBG04389Protein CBG04389. (262 aa)
CBG05024Protein CBG05024. (90 aa)
CBG05224Protein CBG05224. (594 aa)
CBG05229Protein CBG05229. (649 aa)
gck-3Protein CBR-GCK-3. (596 aa)
unc-22Protein CBR-UNC-22. (7455 aa)
kin-4Protein CBR-KIN-4. (1883 aa)
CBG06004Protein CBG06004. (357 aa)
CBG06575Protein CBG06575. (330 aa)
ikke-1Protein CBR-IKKE-1. (828 aa)
CBG06934Protein CBG06934; Belongs to the protein kinase superfamily. (428 aa)
kin-20Protein CBR-KIN-20; Belongs to the protein kinase superfamily. (490 aa)
mbk-1Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1; Possible role in the function of olfactory neurons. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. (904 aa)
CBG07548Protein CBG07548. (304 aa)
sad-1Protein CBR-SAD-1. (931 aa)
CBG07290Protein CBG07290. (348 aa)
CBG07288Protein CBG07288. (379 aa)
CBG07267Protein CBG07267. (315 aa)
CBG07264Protein CBG07264. (300 aa)
pdk-1Protein CBR-PDK-1. (644 aa)
CBG08151Protein CBG08151; Belongs to the protein kinase superfamily. (401 aa)
rskn-2Ribosomal protein S6 kinase. (772 aa)
CBG08225Protein CBG08225. (795 aa)
CBG08226Protein CBG08226. (865 aa)
ttbk-5Protein CBG08492. (376 aa)
CBG08881Protein CBG08881. (199 aa)
CBG08942Protein CBG08942. (300 aa)
CBG09052Protein CBG09052; Belongs to the protein kinase superfamily. (365 aa)
CBG09038Protein CBG09038. (394 aa)
CBG08984Protein CBG08984; Belongs to the protein kinase superfamily. (359 aa)
CBG09188Protein CBG09188. (398 aa)
akt-1Non-specific serine/threonine protein kinase. (605 aa)
ttbk-7Protein CBG09510. (796 aa)
CBG09309Protein CBG09309. (311 aa)
tlk-1Protein CBR-TLK-1. (981 aa)
CBG10201Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (370 aa)
CBG10487Protein CBG10487. (284 aa)
CBG10613Protein CBG10613. (292 aa)
CBG10617Protein CBG10617. (293 aa)
CBG10779Protein CBG10779. (492 aa)
CBG10975Protein CBG10975. (437 aa)
CBG11137Protein CBG11137. (262 aa)
CBG11140Protein CBG11140. (977 aa)
CBG11150Protein CBG11150; Belongs to the protein kinase superfamily. (339 aa)
CBG11420Protein CBG11420. (1136 aa)
CBG11274Protein CBG11274. (326 aa)
CBG11811Protein CBG11811. (295 aa)
CBG11832Protein CBG11832. (271 aa)
ttbk-2Protein CBR-TTBK-2. (311 aa)
csnk-1Protein CBR-CSNK-1; Belongs to the protein kinase superfamily. (460 aa)
CBG12201Protein CBG12201. (244 aa)
kin-3Protein CBR-KIN-3; Belongs to the protein kinase superfamily. (360 aa)
osr-1Protein CBR-OSR-1. (630 aa)
CBG12889Protein CBG12889. (377 aa)
CBG12477Protein CBG12477. (397 aa)
rskn-1Ribosomal protein S6 kinase. (803 aa)
CBG12561Protein CBG12561; Belongs to the protein kinase superfamily. (202 aa)
CBG12760Protein CBG12760. (423 aa)
CBG12789Protein CBG12789. (365 aa)
CBG12956Protein CBG12956; Belongs to the protein kinase superfamily. (364 aa)
CBG13180Protein CBG13180. (583 aa)
rsks-1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (540 aa)
CBG13263Protein CBG13263. (310 aa)
spe-6Protein CBR-SPE-6. (796 aa)
CBG13435Protein CBG13435. (791 aa)
CBG13774Protein CBG13774; Belongs to the protein kinase superfamily. (366 aa)
CBG13775Protein CBG13775. (143 aa)
mak-2Protein CBR-MAK-2; Belongs to the protein kinase superfamily. (366 aa)
CBG14034Protein CBG14034. (399 aa)
CBG14210Protein CBG14210. (289 aa)
CBG14211Protein CBG14211. (335 aa)
sax-1Serine/threonine-protein kinase sax-1; Acts with sax-2 to restrict the growth of both primary and secondary neurites. Regulates mechanosensory tiling by controlling the termination point of sensory dendrites (By similarity). (472 aa)
CBG14305cAMP-dependent protein kinase, catalytic subunit-like. (385 aa)
hpk-1Protein CBR-HPK-1. (854 aa)
CBG14423Protein CBG14423. (291 aa)
CBG14431Protein CBG14431. (222 aa)
CBG14564Protein CBG14564; Belongs to the protein kinase superfamily. (342 aa)
CBG14903Protein CBG14903. (435 aa)
CBG14958Protein CBG14958. (460 aa)
CBG15339Protein CBG15339. (331 aa)
CBG15618Protein CBG15618. (460 aa)
CBG15660Protein CBG15660; Belongs to the protein kinase superfamily. (299 aa)
CBG16092Protein CBG16092. (472 aa)
CBG16040Protein CBG16040. (748 aa)
sgk-1Serine/threonine-protein kinase sgk-1; Acts downstream of PI3 kinase age-1 and kinase pdk-1 in the daf-2/insulin receptor-like transduction pathway. Essential role in regulating development, stress response, and longevity. Phosphorylates Forkhead-related daf-16 and the longevity-promoting skn-1 transcription factors, which inhibits their entry into the nucleus and antagonizes their function. Acts downstream of rict-1 to regulate fat storage, size, and development. Downstream of age-1 and together with akt-1/2, promotes cell survival during embryonic development. Does not appear to play [...] (464 aa)
CBG16302Non-specific serine/threonine protein kinase. (564 aa)
aak-2Non-specific serine/threonine protein kinase. (641 aa)
CBG16239Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
CBG16237Protein CBG16237. (295 aa)
CBG16151Protein CBG16151. (85 aa)
pkc-2Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (941 aa)
CBG16501Protein CBG16501. (509 aa)
ttbk-4Protein CBG16599. (367 aa)
sek-1Protein CBR-SEK-1; Belongs to the protein kinase superfamily. (352 aa)
pkn-1Protein CBR-PKN-1. (1149 aa)
CBG17114Protein CBG17114. (292 aa)
pek-1Protein CBR-PEK-1. (1115 aa)
CBG18289Protein CBG18289. (316 aa)
CBG18309Protein CBG18309. (438 aa)
CBG18341Protein CBG18341. (389 aa)
CBG18395Protein CBG18395; Belongs to the protein kinase superfamily. (380 aa)
CBG17973Protein CBG17973. (543 aa)
CBG17985Protein CBG17985. (431 aa)
CBG18064Protein CBG18064. (987 aa)
CBG18079Protein CBG18079. (406 aa)
prde-1Protein CBG18603. (553 aa)
CBG18695Protein CBG18695. (379 aa)
CBG19430Protein CBG19430. (317 aa)
CBG19692Protein CBG19692. (554 aa)
CBG19698Protein CBG19698. (742 aa)
CBG19815Protein CBG19815. (290 aa)
CBG19731Protein CBG19731. (368 aa)
CBG19720Protein CBG19720. (362 aa)
CBG20023Protein CBG20023. (195 aa)
CBG20086Protein CBG20086. (361 aa)
kin-19Protein CBR-KIN-19; Belongs to the protein kinase superfamily. (342 aa)
CBG20869Protein CBG20869. (885 aa)
CBG20930Protein CBG20930. (372 aa)
CBG20999Protein CBG20999. (364 aa)
CBG21094Protein CBG21094. (344 aa)
CBG21090Protein CBG21090. (340 aa)
mpk-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa)
wts-1Protein CBR-WTS-1. (898 aa)
CBG21812Protein CBG21812. (1010 aa)
CBG23007Protein CBG23007. (411 aa)
pkc-1Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
CBG25344Protein CBG25344. (78 aa)
CBG26420Protein CBG26420. (123 aa)
air-1Protein CBR-AIR-1.1; Belongs to the protein kinase superfamily. (327 aa)
CBG24470Protein CBG24470. (1179 aa)
CBG24569Protein CBG24569. (182 aa)
air-2Aurora/IPL1-related protein kinase 2; Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation. Required for histone H3 'Ser-10' phosphorylation. Phosphorylates tlk-1 and zen-4 (By similarity). (302 aa)
cdk-4Cyclin-dependent kinase CDK-4/6; Belongs to the protein kinase superfamily. (345 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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