STRINGSTRING
sfxn-1.5 sfxn-1.5 CBG23568 CBG23568 CBG23705 CBG23705 CBG23729 CBG23729 CBG23752 CBG23752 CBG23809 CBG23809 CBG23912 CBG23912 lpd-5 lpd-5 psd-1 psd-1 CBG24154 CBG24154 CBG24187 CBG24187 moma-1 moma-1 immt-2 immt-2 CBG24704 CBG24704 CBG24883 CBG24883 CBG00125 CBG00125 haf-1 haf-1 sfxn-5 sfxn-5 hsp-75 hsp-75 bcs-1 bcs-1 CBG01005 CBG01005 Cbr-sdhb-1 Cbr-sdhb-1 sdhb-1 sdhb-1 sfxn-1.2 sfxn-1.2 cox-11 cox-11 micu-1 micu-1 timm-17b.1 timm-17b.1 gfrp-1 gfrp-1 cox-6c cox-6c isp-1 isp-1 CBG01548 CBG01548 immt-1 immt-1 CBG02223 CBG02223 CBG03221 CBG03221 sdhd-1 sdhd-1 nuo-1 nuo-1 cox-15 cox-15 cchl-1 cchl-1 CBG02935 CBG02935 samp-1 samp-1 sfxn-1.4 sfxn-1.4 romo-1 romo-1 CBG02643 CBG02643 CBG02642 CBG02642 phb-2 phb-2 CBG02478 CBG02478 CBG03436 CBG03436 sco-1 sco-1 abtm-1 abtm-1 cps-6 cps-6 dhod-1 dhod-1 nduf-5 nduf-5 Cbr-tag-316 Cbr-tag-316 CBG03753 CBG03753 cox-5b cox-5b cox-7c cox-7c CBG04402 CBG04402 CBG04403 CBG04403 CBG04468 CBG04468 dhs-22 dhs-22 hpo-12 hpo-12 acl-3 acl-3 CBG06101 CBG06101 nuaf-3 nuaf-3 CBG06020 CBG06020 cec-5 cec-5 cec-4 cec-4 dif-1 dif-1 nuo-5 nuo-5 CBG06677 CBG06677 CBG06846 CBG06846 pde-2 pde-2 CBG07090 CBG07090 misc-1 misc-1 gas-1 gas-1 emre-1 emre-1 ucr-2.2 ucr-2.2 unc-84 unc-84 sel-12 sel-12 cyc-1 cyc-1 CBG08332 CBG08332 CBG08349 CBG08349 cox-18 cox-18 atp-1 atp-1 mcu-1 mcu-1 CBG09342 CBG09342 CBG09795 CBG09795 CBG09820 CBG09820 CBG09850 CBG09850 nuo-6 nuo-6 asg-2 asg-2 ddl-3 ddl-3 CBG11107 CBG11107 CBG11518 CBG11518 letm-1 letm-1 CBG11327 CBG11327 sfxn-1.3 sfxn-1.3 CBG11706 CBG11706 hsp-60 hsp-60 mpc-2 mpc-2 hop-1 hop-1 CBG11960 CBG11960 CBG12180 CBG12180 coq-5 coq-5 tin-13 tin-13 lmn-1 lmn-1 nduf-7 nduf-7 atp-3 atp-3 coq-1 coq-1 asg-1 asg-1 sdha-2 sdha-2 CBG12806 CBG12806 tin-44 tin-44 CBG12599 CBG12599 CBG12637 CBG12637 nuo-2 nuo-2 sod-2 sod-2 CBG12981 CBG12981 immp-1 immp-1 CBG13312 CBG13312 coa-3 coa-3 chch-3 chch-3 cec-8 cec-8 rbm-39 rbm-39 CBG13913 CBG13913 CBG13879 CBG13879 asb-2 asb-2 CBG14786 CBG14786 spg-7 spg-7 rom-5 rom-5 hlh-33 hlh-33 nemp-1 nemp-1 CBG15187 CBG15187 crls-1 crls-1 timm-23 timm-23 CBG15682 CBG15682 cox-5a cox-5a ucr-2.1 ucr-2.1 CBG16473 CBG16473 coq-2 coq-2 nuo-4 nuo-4 CBG16820 CBG16820 sfxn-2 sfxn-2 CBG16942 CBG16942 CBG17053 CBG17053 CBG17210 CBG17210 CBG17734 CBG17734 CBG17732 CBG17732 sun-1 sun-1 hpl-2 hpl-2 acdh-11 acdh-11 ymel-1 ymel-1 coq-8 coq-8 mel-28 mel-28 asb-1 asb-1 mpc-1 mpc-1 CBG18137 CBG18137 ucr-2.3 ucr-2.3 atad-3 atad-3 CBG18827 CBG18827 atp-4 atp-4 coq-6 coq-6 let-721 let-721 nduf-2.2 nduf-2.2 CBG19690 CBG19690 cox-4 cox-4 glf-1 glf-1 CBG20020 CBG20020 CBG20119 CBG20119 CBG20158 CBG20158 eat-3 eat-3 nduf-9 nduf-9 oxa-1 oxa-1 ant-1.2 ant-1.2 nduf-6 nduf-6 CBG20679 CBG20679 mrpl-37 mrpl-37 CBG20772 CBG20772 CBG20773 CBG20773 CBG20908 CBG20908 atp-2 atp-2 ant-1.1 ant-1.1 CBG21200 CBG21200 clk-1 clk-1 CBG21259 CBG21259 nuo-3 nuo-3 coq-3 coq-3 slc-25a26 slc-25a26 hpo-18 hpo-18 phb-1 phb-1 emr-1 emr-1 sft-1 sft-1 CBG22669 CBG22669 sdha-1 sdha-1 cox-6a cox-6a dpy-19 dpy-19 CBG23535 CBG23535 CBG23452 CBG23452 CBG23451 CBG23451 CBG23414 CBG23414 bus-18 bus-18 CBG23256 CBG23256 atp-5 atp-5 CBG26013 CBG26013 CBG28046 CBG28046 CBG28141 CBG28141 CBG25951 CBG25951 CBG27170 CBG27170 coq-4.1 coq-4.1 CBG29109 CBG29109 spe-4 spe-4 CBG29118 CBG29118 Cbr-exos-4.1 Cbr-exos-4.1 mev-1 mev-1 sir-2.1 sir-2.1 CBG21207 CBG21207 CBG20693 CBG20693 ddp-1 ddp-1 dnj-21 dnj-21 tin-10 tin-10 scpl-4 scpl-4 tin-9.1 tin-9.1 CBG04116 CBG04116 CBG03233 CBG03233 mfn-1 mfn-1 CBG00135 CBG00135 nd2 nd2 ctb-1 ctb-1 cox-2 cox-2 nd1 nd1 atp6 atp6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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sfxn-1.5Sidoreflexin. (324 aa)
CBG23568Protein CBG23568. (130 aa)
CBG23705COA8 family protein CBG23705, mitochondrial; May be required for cytochrome c complex (COX) assembly and function, COX being the terminal component of the mitochondrial respiratory chain; Belongs to the COA8 family. (142 aa)
CBG23729Protein CBG23729. (287 aa)
CBG23752Protein CBG23752. (330 aa)
CBG23809Protein CBG23809. (60 aa)
CBG23912Protein CBG23912. (219 aa)
lpd-5Protein CBR-LPD-5. (176 aa)
psd-1Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (348 aa)
CBG24154Protein CBG24154. (212 aa)
CBG24187Protein CBG24187; Belongs to the mitochondrial carrier (TC 2.A.29) family. (690 aa)
moma-1MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (202 aa)
immt-2MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (642 aa)
CBG24704Protein CBG24704. (286 aa)
CBG24883Protein CBG24883. (334 aa)
CBG00125Protein CBG00125; Belongs to the peroxisomal membrane protein PXMP2/4 family. (127 aa)
haf-1Protein CBR-HAF-1. (699 aa)
sfxn-5Protein CBR-SFXN-5. (593 aa)
hsp-75Protein CBG00585. (672 aa)
bcs-1Protein CBG00560; Belongs to the AAA ATPase family. (441 aa)
CBG01005Protein CBG01005. (153 aa)
Cbr-sdhb-1Protein CBG00873. (442 aa)
sdhb-1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (282 aa)
sfxn-1.2Sidoreflexin. (329 aa)
cox-11Protein CBG01804. (426 aa)
micu-1Calcium uptake protein 1 homolog, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU). Belongs to the MICU1 family. MICU1 subfamily. (533 aa)
timm-17b.1Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (181 aa)
gfrp-1Protein CBR-GFRP-1. (169 aa)
cox-6cProtein CBG01648. (90 aa)
isp-1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa)
CBG01548Protein CBG01548. (177 aa)
immt-1MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (754 aa)
CBG02223Protein CBG02223. (260 aa)
CBG03221Protein CBG03221. (103 aa)
sdhd-1Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (145 aa)
nuo-1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (479 aa)
cox-15Protein CBG02945. (395 aa)
cchl-1Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (281 aa)
CBG02935Protein CBG02935. (214 aa)
samp-1Protein CBG02931. (552 aa)
sfxn-1.4Sidoreflexin. (326 aa)
romo-1Protein CBR-RMO-1. (83 aa)
CBG02643Protein CBG02643. (161 aa)
CBG02642Protein CBG02642. (102 aa)
phb-2Prohibitin. (294 aa)
CBG02478Protein CBG02478. (186 aa)
CBG03436Protein CBG03436; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
sco-1Protein CBR-SCO-1. (318 aa)
abtm-1Protein CBR-ABTM-1. (878 aa)
cps-6Endonuclease. (310 aa)
dhod-1Protein CBR-DHOD-1. (426 aa)
nduf-5Protein CBR-NDUF-5. (121 aa)
Cbr-tag-316Protein CBR-TAG-316; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
CBG03753Protein CBG03753; Belongs to the mitochondrial carrier (TC 2.A.29) family. (400 aa)
cox-5bProtein CBR-CCO-1. (132 aa)
cox-7cProtein CBG03801. (84 aa)
CBG04402Protein CBG04402. (103 aa)
CBG04403Protein CBG04403. (189 aa)
CBG04468Protein CBG04468. (276 aa)
dhs-22Protein CBR-DHS-22; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (333 aa)
hpo-12Protein CBR-HPO-12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (648 aa)
acl-3Tafazzin family protein; Belongs to the taffazin family. (248 aa)
CBG06101Protein CBG06101. (210 aa)
nuaf-3Protein CBR-NUAF-3. (208 aa)
CBG06020Protein CBG06020; Belongs to the mitochondrial carrier (TC 2.A.29) family. (340 aa)
cec-5Protein CBR-CEC-5. (398 aa)
cec-4Protein CBR-CEC-4. (311 aa)
dif-1Protein CBR-DIF-1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
nuo-5Protein CBR-NUO-5; Belongs to the complex I 75 kDa subunit family. (725 aa)
CBG06677Protein CBG06677. (456 aa)
CBG06846Protein CBG06846. (190 aa)
pde-2Phosphodiesterase. (959 aa)
CBG07090Protein CBG07090. (228 aa)
misc-1Protein CBG07018; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
gas-1Protein CBR-GAS-1; Belongs to the complex I 49 kDa subunit family. (482 aa)
emre-1Protein CBR-TAG-299. (91 aa)
ucr-2.2Protein CBR-UCR-2.2. (483 aa)
unc-84Protein CBR-UNC-84. (1115 aa)
sel-12Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (450 aa)
cyc-1Protein CBR-CYC-1. (285 aa)
CBG08332Protein CBG08332. (374 aa)
CBG08349Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (116 aa)
cox-18Protein CBG08423. (311 aa)
atp-1ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (579 aa)
mcu-1Protein CBR-MCU-1. (333 aa)
CBG09342Protein CBG09342; Belongs to the mitochondrial carrier (TC 2.A.29) family. (284 aa)
CBG09795GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (237 aa)
CBG09820Protein CBG09820. (139 aa)
CBG09850NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (183 aa)
nuo-6Protein CBR-NUO-6. (172 aa)
asg-2Protein CBR-ASG-2. (131 aa)
ddl-3Protein CBR-DDL-3. (403 aa)
CBG11107Protein CBG11107. (896 aa)
CBG11518Protein CBG11518. (239 aa)
letm-1Protein CBR-LETM-1. (777 aa)
CBG11327Protein CBG11327. (548 aa)
sfxn-1.3Sidoreflexin. (329 aa)
CBG11706ATP synthase lipid-binding protein, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (116 aa)
hsp-60Protein CBR-HSP-60; Belongs to the chaperonin (HSP60) family. (567 aa)
mpc-2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (132 aa)
hop-1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (358 aa)
CBG11960Protein CBG11960. (123 aa)
CBG12180Protein CBG12180. (170 aa)
coq-52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (270 aa)
tin-13Protein CBR-TIN-13; Belongs to the small Tim family. (108 aa)
lmn-1Protein CBR-LMN-1; Belongs to the intermediate filament family. (565 aa)
nduf-7Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (199 aa)
atp-3Protein CBR-ATP-3. (207 aa)
coq-1Protein CBR-COQ-1; Belongs to the FPP/GGPP synthase family. (392 aa)
asg-1Protein CBR-ASG-1. (131 aa)
sdha-2Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa)
CBG12806Protein CBG12806. (171 aa)
tin-44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (425 aa)
CBG12599Protein CBG12599. (259 aa)
CBG12637Protein CBG12637. (571 aa)
nuo-2Protein CBR-NUO-2; Belongs to the complex I 30 kDa subunit family. (399 aa)
sod-2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
CBG12981Protein CBG12981. (268 aa)
immp-1Protein CBR-IMMP-1. (156 aa)
CBG13312Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (133 aa)
coa-3Protein CBG13442. (137 aa)
chch-3Protein CBR-CHCH-3. (157 aa)
cec-8Protein CBR-CEC-8. (631 aa)
rbm-39Protein CBG13969. (586 aa)
CBG13913NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (146 aa)
CBG13879Protein CBG13879. (72 aa)
asb-2Protein CBR-ASB-2. (305 aa)
CBG14786Protein CBG14786. (83 aa)
spg-7Protein CBR-SPG-7. (814 aa)
rom-5Protein CBR-ROM-5. (336 aa)
hlh-33Protein CBR-HLH-33. (339 aa)
nemp-1Protein CBG15202. (562 aa)
CBG15187Protein CBG15187. (45 aa)
crls-1Protein CBR-CRLS-1. (221 aa)
timm-23Protein CBG15355. (243 aa)
CBG15682Protein CBG15682. (462 aa)
cox-5aProtein CBR-CCO-2. (174 aa)
ucr-2.1Protein CBR-UCR-2.1. (410 aa)
CBG16473Protein CBG16473. (299 aa)
coq-24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (405 aa)
nuo-4NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (436 aa)
CBG16820Protein CBG16820. (749 aa)
sfxn-2Sidoreflexin. (319 aa)
CBG16942Protein CBG16942. (193 aa)
CBG17053MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (95 aa)
CBG17210Protein CBG17210; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)
CBG17734Protein CBG17734. (528 aa)
CBG17732Protein CBG17732. (415 aa)
sun-1Protein CBR-SUN-1. (482 aa)
hpl-2Protein CBR-HPL-2. (305 aa)
acdh-11Protein CBG18356. (616 aa)
ymel-1Protein CBR-YMEL-1; Belongs to the AAA ATPase family. (670 aa)
coq-8Protein CBR-COQ-8. (756 aa)
mel-28Protein CBR-MEL-28. (1559 aa)
asb-1Protein CBR-ASB-1. (301 aa)
mpc-1Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (154 aa)
CBG18137Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily. (645 aa)
ucr-2.3Protein CBR-UCR-2.3. (433 aa)
atad-3Protein CBR-ATAD-3. (596 aa)
CBG18827Protein CBG18827. (92 aa)
atp-4Protein CBR-ATP-4. (129 aa)
coq-6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (451 aa)
let-721Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (597 aa)
nduf-2.2Protein CBR-NDUF-2.2; Belongs to the complex I 49 kDa subunit family. (474 aa)
CBG19690Protein CBG19690; Belongs to the complex I LYR family. (163 aa)
cox-4Protein CBG19770. (175 aa)
glf-1Protein CBR-GLF-1. (476 aa)
CBG20020Protein CBG20020. (150 aa)
CBG20119Protein CBG20119. (87 aa)
CBG20158Protein CBG20158; Belongs to the mitochondrial carrier (TC 2.A.29) family. (365 aa)
eat-3Protein CBR-EAT-3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (969 aa)
nduf-9Protein CBG20301. (428 aa)
oxa-1Protein CBG20396. (301 aa)
ant-1.2Protein CBG20451; Belongs to the mitochondrial carrier (TC 2.A.29) family. (216 aa)
nduf-6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (140 aa)
CBG20679Protein CBG20679. (199 aa)
mrpl-37Protein CBR-MRPL-37. (424 aa)
CBG20772Protein CBG20772. (164 aa)
CBG20773Protein CBG20773. (90 aa)
CBG20908Protein CBG20908. (88 aa)
atp-2ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (537 aa)
ant-1.1Protein CBR-TAG-61; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa)
CBG21200Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (75 aa)
clk-15-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa)
CBG21259Protein CBG21259; Belongs to the BI1 family. (292 aa)
nuo-3Protein CBR-NUO-3. (131 aa)
coq-3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (262 aa)
slc-25a26Protein CBG21724; Belongs to the mitochondrial carrier (TC 2.A.29) family. (271 aa)
hpo-18Protein CBR-HPO-18. (54 aa)
phb-1Prohibitin. (275 aa)
emr-1Protein CBR-EMR-1. (190 aa)
sft-1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (317 aa)
CBG22669MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (102 aa)
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (645 aa)
cox-6aCytochrome c oxidase subunit 6A, mitochondrial. (129 aa)
dpy-19C-mannosyltransferase dpy-19; C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins such as unc-5 and mig-21. Mediates the attachment of alpha-mannose in C-C linkage to the C2 of the indole ring of tryptophan. C-mannosylation takes place in the endoplasmic reticulum and frequently found in thrombospondin (TSP) type-1 repeats and in the WSXWS motif of type I cytokine receptors. Required to orient neuroblasts QL and QR correctly on the anterior/posterior (A/P) axis: QL and QR are born in the same A/P position, but polarize and migrate left/right as [...] (687 aa)
CBG23535Protein CBG23535; Belongs to the mitochondrial carrier (TC 2.A.29) family. (340 aa)
CBG23452Protein CBG23452. (107 aa)
CBG23451Protein CBG23451. (184 aa)
CBG23414Protein CBG23414. (1631 aa)
bus-18Protein CBR-BUS-18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (834 aa)
CBG23256Protein CBG23256. (514 aa)
atp-5Protein CBR-ATP-5. (191 aa)
CBG26013Protein CBG26013. (430 aa)
CBG28046Protein CBG28046. (156 aa)
CBG28141Mitochondrial fission process protein 1; Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity). Belongs to the MTFP1 family. (162 aa)
CBG25951Protein CBG25951. (73 aa)
CBG27170Protein CBG27170. (200 aa)
coq-4.1Ubiquinone biosynthesis protein coq-4.1, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. (227 aa)
CBG29109Protein CBG29109. (407 aa)
spe-4Protein CBR-SPE-4. (483 aa)
CBG29118Protein CBG29118. (160 aa)
Cbr-exos-4.1Protein CBR-EXOS-4.1, isoform b. (114 aa)
mev-1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Mediates resistance to enteropathogenic E.coli infection (By similarity); Belongs to the cytochrome b560 family. (184 aa)
sir-2.1NAD-dependent protein deacetylase sir-2.1; NAD-dependent deacetylase. Required for a reduction of the 'Lys-16' acetylation of histone H4 (H4K16ac) on dosage-compensated X chromosomes in hermaphrodites. Functions upstream of daf-16 in the insulin-like signaling pathway, promoting daf-16 mediated transcriptional activation and increased life-span. May also regulate life-span independently of daf-16 by modulating the transcription of genes involved in the stress response of the endoplasmic reticulum (ER). Acts upstream of the nicotinic acid metabolism pathway, which may be linked to the r [...] (602 aa)
CBG21207Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. (138 aa)
CBG20693Mpv17-like protein; Involved in mitochondria homeostasis; Belongs to the peroxisomal membrane protein PXMP2/4 family. (181 aa)
ddp-1Mitochondrial import inner membrane translocase subunit Tim8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The ddp- 1/tim-8-tim-13 complex mediates the import of some [...] (83 aa)
dnj-21Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). (111 aa)
tin-10Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (86 aa)
scpl-4Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (456 aa)
tin-9.1Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. (78 aa)
CBG04116Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (321 aa)
CBG03233Probable NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (160 aa)
mfn-1Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
CBG00135Probable calcium-binding mitochondrial carrier CBG00135; Calcium-dependent mitochondrial solute carrier. Belongs to the mitochondrial carrier (TC 2.A.29) family. (532 aa)
nd2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (282 aa)
ctb-1Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (370 aa)
cox-2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (231 aa)
nd1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (291 aa)
atp6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (199 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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