Your Input: | |
| | itr-1 | Protein CBR-ITR-1, isoform a. (2921 aa) |
| | CBG27040 | Protein CBG27040. (268 aa) |
| | ccf-1 | Protein CBG13315. (315 aa) |
| | spe-4 | Protein CBR-SPE-4. (483 aa) |
| | emo-1 | Protein CBR-EMO-1. (68 aa) |
| | hars-1 | Protein CBR-HARS-1. (556 aa) |
| | CBG26279 | Protein CBG26279. (303 aa) |
| | CBG25215 | Protein CBG25215. (112 aa) |
| | CBG27110 | Protein CBG27110. (104 aa) |
| | CBG27374 | Protein CBG27374. (172 aa) |
| | CBG26743 | Protein CBG26743. (197 aa) |
| | aph-1 | Protein CBR-APH-1. (330 aa) |
| | CBG00587 | Protein CBG00587. (444 aa) |
| | pptr-2 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (556 aa) |
| | CBG23216 | Protein CBG23216. (313 aa) |
| | skp-1 | Protein CBR-SKP-1. (534 aa) |
| | rnp-1 | Protein CBR-RNP-1. (286 aa) |
| | pptr-1 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (531 aa) |
| | CBG22507 | Protein CBG22507. (151 aa) |
| | CBG22502 | Protein CBG22502. (675 aa) |
| | puf-6.4 | Protein CBG22348. (395 aa) |
| | CBG22294 | Protein CBG22294. (260 aa) |
| | CBG22257 | Protein CBG22257. (370 aa) |
| | rtcb-1 | RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family. (457 aa) |
| | ppfr-1 | Protein CBR-PPFR-1. (1472 aa) |
| | csn-2 | Protein CBR-CSN-2. (368 aa) |
| | gsa-1 | Protein CBR-GSA-1. (326 aa) |
| | phb-1 | Prohibitin. (275 aa) |
| | lin-41 | Protein CBR-LIN-41. (934 aa) |
| | oma-2 | Protein CBR-OMA-2. (379 aa) |
| | eri-3 | Protein CBR-ERI-3. (577 aa) |
| | CBG21613 | Protein CBG21613. (303 aa) |
| | CBG21443 | Protein CBG21443. (462 aa) |
| | CBG21334 | Protein CBG21334. (102 aa) |
| | lis-1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (390 aa) |
| | mpk-1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (374 aa) |
| | nos-1 | Protein CBR-NOS-1; Belongs to the nanos family. (246 aa) |
| | CBG20875 | Protein CBG20875. (177 aa) |
| | Cbr-gsp-4 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (242 aa) |
| | mog-4 | Protein CBR-MOG-4. (1007 aa) |
| | rab-7 | Protein CBR-RAB-7. (209 aa) |
| | csc-1 | Protein CBR-CSC-1. (204 aa) |
| | egg-3 | Protein CBR-EGG-3. (419 aa) |
| | ekl-1 | Protein CBR-EKL-1. (644 aa) |
| | cdk-9 | Protein CBR-CDK-9; Belongs to the protein kinase superfamily. (464 aa) |
| | CBG20325 | Protein CBG20325. (303 aa) |
| | cyp-42a1 | Protein CBR-CYP-42A1; Belongs to the cytochrome P450 family. (512 aa) |
| | CBG20238 | Protein CBG20238. (157 aa) |
| | elt-1 | Protein CBR-ELT-1. (428 aa) |
| | csn-5 | Protein CBR-CSN-5. (367 aa) |
| | bec-1 | Protein CBR-BEC-1. (375 aa) |
| | CBG19457 | Protein CBG19457. (152 aa) |
| | gna-2 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (349 aa) |
| | try-5 | Protein CBR-TRY-5; Belongs to the peptidase S1 family. (305 aa) |
| | gck-1 | Protein CBR-GCK-1. (898 aa) |
| | CBG19039 | Protein CBG19039. (304 aa) |
| | spe-39 | Protein CBR-SPE-39. (523 aa) |
| | mag-1 | Protein CBR-MAG-1. (153 aa) |
| | unc-116 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (843 aa) |
| | CBG18143 | Protein CBG18143. (208 aa) |
| | trp-1 | Protein CBR-TRP-1; Belongs to the transient receptor (TC 1.A.4) family. (1055 aa) |
| | pan-1 | Protein CBR-PAN-1. (598 aa) |
| | atx-2 | Protein CBR-ATX-2. (1051 aa) |
| | CBG18333 | Protein CBG18333. (497 aa) |
| | ran-1 | GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa) |
| | CBG18295 | Protein CBG18295. (477 aa) |
| | cul-2 | Protein CBR-CUL-2; Belongs to the cullin family. (850 aa) |
| | cyk-4 | Protein CBR-CYK-4. (676 aa) |
| | CBG17851 | Protein CBG17851. (203 aa) |
| | cyb-1 | Protein CBR-CYB-1; Belongs to the cyclin family. (353 aa) |
| | csr-1 | Protein CBR-CSR-1. (1003 aa) |
| | arf-3 | Protein CBR-ARF-3; Belongs to the small GTPase superfamily. Arf family. (180 aa) |
| | CBG17113 | Protein CBG17113. (296 aa) |
| | eri-5 | Protein CBR-ERI-5. (564 aa) |
| | mek-1 | Protein CBR-MEK-1. (463 aa) |
| | ten-1 | Protein CBR-TEN-1. (2909 aa) |
| | larp-1 | Protein CBR-LARP-1. (1159 aa) |
| | cyk-1 | Protein CBR-CYK-1. (1477 aa) |
| | cil-1 | Protein CBR-CIL-1. (398 aa) |
| | let-711 | Protein CBR-LET-711. (2627 aa) |
| | mrg-1 | Protein CBR-MRG-1. (354 aa) |
| | stim-1 | Protein CBR-STIM-1. (550 aa) |
| | CBG15591 | Protein CBG15591. (344 aa) |
| | spe-9 | Protein CBR-SPE-9. (658 aa) |
| | dss-1 | Probable 26S proteasome complex subunit dss-1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Has an essential role in oogenesis and larval growth. Required for intestinal function and default lifespan (By similarity). (76 aa) |
| | fer-1 | Protein CBR-FER-1. (2126 aa) |
| | ipp-5 | Protein CBR-IPP-5. (408 aa) |
| | ceh-18 | POU domain protein. (545 aa) |
| | ubxn-2 | Protein CBR-UBXN-2. (702 aa) |
| | gtsf-1 | Protein CBG13683. (181 aa) |
| | CBG13640 | Protein CBG13640. (1232 aa) |
| | eri-1 | Protein CBR-ERI-1. (578 aa) |
| | vab-1 | Protein CBR-VAB-1. (1118 aa) |
| | Cbr-kel-10 | Protein CBR-KEL-10. (524 aa) |
| | spe-6 | Protein CBR-SPE-6. (796 aa) |
| | pen-2 | Protein CBR-PEN-2. (101 aa) |
| | puf-6.1 | Protein CBG13175. (394 aa) |
| | puf-8 | Protein CBR-PUF-8. (535 aa) |
| | gld-3 | Protein CBR-GLD-3. (956 aa) |
| | moa-2 | Protein CBG13037. (219 aa) |
| | cdk-11.1 | Protein CBG12984. (711 aa) |
| | spe-19 | Protein CBR-SPE-19. (323 aa) |
| | CBG12665 | Protein CBG12665. (236 aa) |
| | glh-1 | Protein CBR-GLH-1. (817 aa) |
| | dnj-4 | Protein CBR-DNJ-4. (274 aa) |
| | rpn-10 | Protein CBR-RPN-10. (347 aa) |
| | spe-11 | Protein CBR-SPE-11. (289 aa) |
| | fcp-1 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (653 aa) |
| | lmn-1 | Protein CBR-LMN-1; Belongs to the intermediate filament family. (565 aa) |
| | Cbr-tag-250 | Protein CBR-TAG-250. (620 aa) |
| | CBG12189 | Protein CBG12189. (215 aa) |
| | anc-1 | Protein CBR-ANC-1. (3414 aa) |
| | inx-21 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (468 aa) |
| | inx-22 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (454 aa) |
| | prg-1 | Protein CBR-PRG-1; Belongs to the argonaute family. (826 aa) |
| | Cbr-unc-13 | Protein CBG11945. (394 aa) |
| | unc-13 | Protein CBR-UNC-13. (2250 aa) |
| | inx-14 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (563 aa) |
| | egg-4 | Protein CBR-EGG-4. (752 aa) |
| | glh-4 | Protein CBR-GLH-4. (1192 aa) |
| | chs-1 | Protein CBR-CHS-1. (1319 aa) |
| | puf-6.2 | Protein CBG11800. (437 aa) |
| | ani-1 | Protein CBR-ANI-1. (1199 aa) |
| | CBG11554 | Protein CBG11554. (266 aa) |
| | CBG11256 | Protein CBG11256. (254 aa) |
| | rde-12 | Protein CBG11510. (1248 aa) |
| | bir-2 | Protein CBR-BIR-2. (306 aa) |
| | mes-2 | Protein CBR-MES-2. (930 aa) |
| | mat-1 | Protein CBR-MAT-1. (746 aa) |
| | elpc-1 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1214 aa) |
| | Cbr-tag-300 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (501 aa) |
| | iff-1 | Eukaryotic translation initiation factor 5A. (162 aa) |
| | vha-1 | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (166 aa) |
| | Cbr-tag-76 | Protein CBR-TAG-76. (1076 aa) |
| | CBG09901 | Protein CBG09901. (2006 aa) |
| | laf-1 | Protein CBR-LAF-1; Belongs to the DEAD box helicase family. (653 aa) |
| | spe-41 | Protein CBR-SPE-41. (807 aa) |
| | CBG09790 | Protein CBG09790. (516 aa) |
| | mut-14 | Protein CBR-MUT-14; Belongs to the DEAD box helicase family. (527 aa) |
| | acy-4 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1000 aa) |
| | klc-2 | Protein CBR-KLC-2. (522 aa) |
| | CBG09367 | Protein CBG09367. (471 aa) |
| | noca-1 | Protein CBR-NOCA-1. (861 aa) |
| | CBG09430 | Protein CBG09430. (223 aa) |
| | klc-1 | Protein CBG09436. (530 aa) |
| | spe-10 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (365 aa) |
| | CBG09703 | Protein CBG09703. (277 aa) |
| | plk-1 | Serine/threonine-protein kinase PLK. (661 aa) |
| | cgh-1 | Protein CBR-CGH-1; Belongs to the DEAD box helicase family. (429 aa) |
| | par-3 | Protein CBR-PAR-3. (1332 aa) |
| | npp-10 | Protein CBR-NPP-10. (1684 aa) |
| | dnc-2 | Protein CBR-DNC-2. (331 aa) |
| | ddx-23 | Protein CBG09074; Belongs to the DEAD box helicase family. (747 aa) |
| | syx-4 | Protein CBR-SYX-4; Belongs to the syntaxin family. (293 aa) |
| | par-6 | Protein CBR-PAR-6. (305 aa) |
| | egg-1 | LDL receptor repeat-containing protein egg-1; Probable receptor which is required for the oocyte-to-zygote transition although its exact function is controversial (By similarity). Seems to be required for fertilization probably by promoting the interaction or fusion between sperm and oocyte. Conversely, shown to be dispensable for fertilization but required for the formation of a continuous and cohesive eggshell chitin layer by maintaining a homogenous distribution of chitin synthase chs-1 at the unfertilized oocyte cell membrane (By similarity). Appears to recruit or maintain together [...] (636 aa) |
| | csn-4 | Protein CBR-CSN-4. (412 aa) |
| | drh-3 | Protein CBR-DRH-3. (846 aa) |
| | aex-3 | Protein CBR-AEX-3. (1500 aa) |
| | stau-1 | Protein CBG08071. (693 aa) |
| | tsp-9 | Tetraspanin. (233 aa) |
| | CBG08010 | Protein CBG08010. (155 aa) |
| | gsk-3 | Glycogen synthase kinase-3; Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation. Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense. Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres. Thought to be a branch point in these processes as proteins downstream are not required. Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting [...] (359 aa) |
| | pab-2 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (685 aa) |
| | CBG07471 | Protein CBG07471. (1113 aa) |
| | CBG07472 | Protein CBG07472. (459 aa) |
| | CBG07476 | Protein CBG07476. (346 aa) |
| | CBG07477 | Protein CBG07477. (580 aa) |
| | CBG07478 | Protein CBG07478. (207 aa) |
| | CBG07024 | Protein CBG07024. (934 aa) |
| | ubxn-3 | Protein CBR-UBXN-3. (592 aa) |
| | snap-29 | Protein CBR-SNAP-29. (277 aa) |
| | CBG06875 | Protein CBG06875. (310 aa) |
| | rab-6.1 | Protein CBR-RAB-6.1. (205 aa) |
| | glp-1 | Protein CBR-GLP-1. (1326 aa) |
| | puf-6.3 | Protein CBG06390. (340 aa) |
| | lip-1 | Protein CBR-LIP-1. (376 aa) |
| | pam-1 | Aminopeptidase. (899 aa) |
| | ima-3 | Importin subunit alpha; Belongs to the importin alpha family. (513 aa) |
| | CBG05915 | Protein CBG05915. (546 aa) |
| | dnc-1 | Protein CBR-DNC-1. (1325 aa) |
| | lin-3 | Protein CBR-LIN-3. (450 aa) |
| | let-60 | Protein CBR-LET-60. (184 aa) |
| | inx-8 | Innexin; Structural component of the gap junctions. Belongs to the pannexin family. (390 aa) |
| | let-92 | Serine/threonine-protein phosphatase. (318 aa) |
| | spe-17 | Protein CBR-SPE-17. (126 aa) |
| | csn-1 | Protein CBR-CSN-1. (580 aa) |
| | gck-3 | Protein CBR-GCK-3. (596 aa) |
| | cyb-3 | Protein CBR-CYB-3; Belongs to the cyclin family. (386 aa) |
| | lag-1 | Protein CBR-LAG-1. (681 aa) |
| | zen-4 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (779 aa) |
| | CBG05455 | Protein CBG05455. (705 aa) |
| | spe-8 | Spermatocyte protein spe-8; Probable non-receptor tyrosine-protein kinase which plays a role in spermatid activation (spermiogenesis) in hermaphrodites. (479 aa) |
| | uaf-1 | Splicing factor U2AF 65 kDa subunit; Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity). (488 aa) |
| | tra-2 | Sex-determining transformer protein 2; Plays a major role in controlling sexual cell fates. Promotes female development in XX animals where it sequesters one or more of the FEM proteins to the membrane thereby freeing the tra-1 protein (a putative transcription factor) to enter the nucleus and promote female development (By similarity). In XO animals it acts as a receptor for her-1 which prevents it from binding to FEM proteins thereby repressing the activity of tra-1 (By similarity). Negatively regulates male development when bound to fem-3 and is required together with tra-1 for prom [...] (1489 aa) |
| | sos-1 | Protein CBR-SOS-1. (339 aa) |
| | tra-1 | Sex-determining transformer protein 1; Plays a major role in controlling sexual phenotype. Terminal global regulator in a well-characterized cascade of sex-determining genes (By similarity). Promotes female development (By similarity). Interacts with tra-2 to promote spermatogenesis. Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development. Association with chromatin and at the fog-3 promoter requires wdr-5.1, and may also require wdr-5.2 (By similarity). With trr-1, activates the fog-3 gene to determ [...] (1165 aa) |
| | sqv-8 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (356 aa) |
| | elpc-3 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5- carbamoylmethyl uridine) (By similarity). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at po [...] (548 aa) |
| | vha-11 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Has roles in embryogenesis and ovulation (By similarity). (385 aa) |
| | arf-1.2 | ADP-ribosylation factor 1-like 2; GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Involved in endoplasmic reticulum dynamics during embryogenesis. Also required for adult germline function (By similarity); Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | mup-2 | Protein CBR-MUP-2. (421 aa) |
| | abl-1 | Tyrosine-protein kinase. (1211 aa) |
| | vps-33.2 | Protein CBR-VPS-33.2; Belongs to the STXBP/unc-18/SEC1 family. (670 aa) |
| | tac-1 | Protein CBR-TAC-1. (262 aa) |
| | icp-1 | Protein CBR-ICP-1. (516 aa) |
| | rme-2 | Protein CBR-RME-2. (929 aa) |
| | riok-1 | Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (515 aa) |
| | mek-2 | Protein CBR-MEK-2; Belongs to the protein kinase superfamily. (387 aa) |
| | vbh-1 | Protein CBR-VBH-1; Belongs to the DEAD box helicase family. (692 aa) |
| | mei-1 | Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. This activity may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. (484 aa) |
| | rsd-6 | Protein CBR-RSD-6. (813 aa) |
| | uri-1 | Protein CBR-URI-1. (447 aa) |
| | ubxn-1 | Protein CBR-UBXN-1. (305 aa) |
| | let-502 | Rho-associated protein kinase let-502; Negatively regulates mel-11 to relieve the inhibition of mlc- 4, allowing contraction of the circumferentially oriented microfilaments in epidermal cells and thereby regulating myosin II contractility during spermathecal contraction, cleavage furrow contraction in early embryos, and embryonic elongation and morphogenesis. Required for P-cell migration. May also play a role in oocyte cellularization (By similarity). (1194 aa) |
| | CBG03928 | Protein CBG03928. (325 aa) |
| | CBG03927 | Protein CBG03927. (280 aa) |
| | sir-2.4 | Protein CBR-SIR-2.4. (324 aa) |
| | Cbr-hpo-40 | Protein CBR-HPO-40. (608 aa) |
| | CBG03621 | Protein CBG03621. (549 aa) |
| | emb-8 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (661 aa) |
| | npp-1 | Protein CBR-NPP-1. (621 aa) |
| | uba-1 | Protein CBR-UBA-1; Belongs to the ubiquitin-activating E1 family. (1114 aa) |
| | CBG03418 | Protein CBG03418. (276 aa) |
| | rack-1 | Protein CBR-RACK-1. (325 aa) |
| | kca-1 | Protein CBR-KCA-1. (423 aa) |
| | atz-1 | Protein CBG03320. (369 aa) |
| | pkc-3 | Protein kinase C-like 3; Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa) |
| | mog-5 | Protein CBR-MOG-5. (1220 aa) |
| | daz-1 | Protein CBR-DAZ-1. (224 aa) |
| | fzy-1 | Protein CBR-FZY-1. (521 aa) |
| | cdc-14.1 | Protein CBG02450. (698 aa) |
| | cdc-14.2 | Protein CBR-CDC-14. (1044 aa) |
| | ify-1 | Protein CBR-IFY-1. (281 aa) |
| | ptp-2 | Protein CBR-PTP-2. (692 aa) |
| | rbbp-5 | Protein CBG02573. (451 aa) |
| | mep-1 | MOG interacting and ectopic P-granules protein 1; Has a broad role in development, specifically in the genetic pathway SynMuvB that negatively regulates specification of the vulval cell fate. Required for fem-3 3'-UTR-mediated repression in the regulation of the sperm/oocyte switch. Acts by regulating the translation of fem-3 mRNA, by binding to its 3'-UTR (By similarity). (880 aa) |
| | phb-2 | Prohibitin. (294 aa) |
| | ani-2 | Protein CBR-ANI-2. (1038 aa) |
| | atg-16.2 | Protein CBR-ATG-16.2. (552 aa) |
| | trr-1 | Transcription-associated protein 1; Influences germ cell fate in hermaphrodites. Acts downstream of tra-2 and tra-3 and through the Tip60 histone acetyltransferase complex to regulate germ cell fate decisions. Required for spermatogenesis and embryonic development. Acts with tra-2 to promote expression of fog-3 and control male tail development. Involved in the negative regulation of vulval development (By similarity). (4115 aa) |
| | rsp-1 | Protein CBR-RSP-1. (304 aa) |
| | rsp-2 | Protein CBR-RSP-2. (256 aa) |
| | CBG02973 | Protein CBG02973. (89 aa) |
| | pro-1 | Pre-rRNA-processing protein pro-1; Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation (By similarity). Required in the soma to promote normal proliferation and prevent germline tumor formation (By similarity). (532 aa) |
| | Cbr-rha-1 | Protein CBR-RHA-1. (1402 aa) |
| | ddx-19 | Protein CBG03203. (1095 aa) |
| | lat-1 | Protein CBR-LAT-1; Belongs to the G-protein coupled receptor 2 family. (1069 aa) |
| | CBG03266 | Protein CBG03266. (318 aa) |
| | pab-1 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (666 aa) |
| | mus-101 | Protein CBR-MUS-101. (1175 aa) |
| | CBG02150 | Protein CBG02150. (727 aa) |
| | CBG02127 | Protein CBG02127. (439 aa) |
| | CBG02011 | Protein CBG02011. (556 aa) |
| | tut-1 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (372 aa) |
| | Cbr-csn-3 | Protein CBR-CSN-3. (750 aa) |
| | CBG01667 | Protein CBG01667. (823 aa) |
| | cif-1 | COP9/Signalosome and eIF3 complex-shared subunit 1; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulat [...] (390 aa) |
| | hoe-1 | Protein CBR-HOE-1. (832 aa) |
| | gcl-1 | Protein CBR-GCL-1. (490 aa) |
| | CBG01772 | Protein CBG01772. (315 aa) |
| | cyp-31a2 | Protein CBR-CYP-31A3; Belongs to the cytochrome P450 family. (495 aa) |
| | csn-6 | Protein CBR-CSN-6. (448 aa) |
| | CBG01467 | Protein CBG01467. (383 aa) |
| | atg-18 | Protein CBR-ATG-18. (406 aa) |
| | fbxa-137 | Protein CBR-FBXA-137. (321 aa) |
| | irld-30 | Protein CBG01133. (405 aa) |
| | let-23 | Receptor protein-tyrosine kinase. (1379 aa) |
| | iff-2 | Eukaryotic translation initiation factor 5A. (162 aa) |
| | puf-5 | Protein CBR-PUF-5. (453 aa) |
| | nst-1 | Protein CBR-NST-1. (567 aa) |
| | rrf-3 | Protein CBR-RRF-3. (1766 aa) |
| | emb-27 | Protein CBR-EMB-27. (669 aa) |
| | zipt-7.1 | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels (By similarity). Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function (By similarity). Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm (By similarity). The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable [...] (392 aa) |
| | CBG00341 | Protein CBG00341. (291 aa) |
| | ego-1 | Protein CBR-EGO-1. (1631 aa) |
| | gld-1 | Protein CBR-GLD-1. (467 aa) |
| | CBG00165 | Protein CBG00165. (652 aa) |
| | nos-2 | Protein CBR-NOS-2; Belongs to the nanos family. (262 aa) |
| | lin-45 | Raf homolog serine/threonine-protein kinase; Protein kinase that participates in the induction of vulva and has a role in fertility and viability. Acts downstream of the Ras protein let-60. Required for progression of developing oocytes through the pachytene stage. Positively regulates lifespan upstream of mek-2 and mpk-1. (811 aa) |
| | drsh-1 | Ribonuclease 3; Executes the initial step of microRNA (miRNA) processing in the nucleus, that is the cleavage of pri-miRNA to release pre-miRNA. Involved in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in fertility. Required for the function or synthesis of the let-7 miRNA (By similarity). Belongs to the ribonuclease III family. (1061 aa) |
| | wee-1.3 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase wee-1.3; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase during oocyte maturation. Required for embryonic development, germline proliferation and initiation of meiosis during spermatogenesis. Required for chromosome structure during mitosis and negative regulation of nuclear envelope breakdown (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. (656 aa) |
| | cpb-1 | Cytoplasmic polyadenylation element-binding protein 1; Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs. Essential for progression through meiosis. Involved in spermatogenesis (By similarity). (585 aa) |
| | fog-1 | Protein CBR-FOG-1. (647 aa) |
| | fem-3 | Sex-determination protein fem-3; Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite animals), it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2. (409 aa) |
| | cye-1 | G1/S-specific cyclin-E; Essential for the control of the cell cycle at the G1/S (start) transition. In association with cdk-2, regulates proliferation, quiescent state and cell fate during the development of several cell lineages. In the embryo, initiates the establishment of cell polarity through the recruitment of the centrosomal proteins spd-2 and spd-5 during prophase. During the development of the vulva, controls the onset of vulval cell terminal differentiation by controlling the duration of G1 phase. During hypoderm development at early larval stages, controls syncytial fate of [...] (518 aa) |
| | fog-3 | Protein CBR-FOG-3. (261 aa) |
| | smn-1 | Protein CBR-SMN-1. (194 aa) |
| | spe-38 | Protein CBG24396. (125 aa) |
| | nud-1 | Protein CBR-NUD-1. (311 aa) |
| | CBG23593 | Protein CBG23593. (439 aa) |
| | Cbr-spe-42 | Protein CBR-SPE-42. (774 aa) |
| | CBG23936 | Protein CBG23936. (1003 aa) |
