(31 nodes) Proteasome accessory complex network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG09111	Protein CBG09111. (197 aa)
	CBG23920	Protein CBG23920; Belongs to the AAA ATPase family. (268 aa)
	rpn-11	Protein CBR-RPN-11. (312 aa)
	rpn-2	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (970 aa)
	rpn-9	Protein CBR-RPN-9. (382 aa)
	rpn-12	Protein CBR-RPN-12. (250 aa)
	rpn-5	Protein CBR-RPN-5. (491 aa)
	CBG04772	Protein CBG04772; Belongs to the AAA ATPase family. (426 aa)
	rpn-1	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (992 aa)
	rpn-6.2	Probable 26S proteasome regulatory subunit rpn-6.2; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn-6.2 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family. (411 aa)
	CBG06852	Protein CBG06852. (116 aa)
	rpt-4	Protein CBR-RPT-4; Belongs to the AAA ATPase family. (398 aa)
	rpt-3	Protein CBR-RPT-3; Belongs to the AAA ATPase family. (417 aa)
	rpt-2	Protein CBR-RPT-2; Belongs to the AAA ATPase family. (443 aa)
	CBG11069	Protein CBG11069; Belongs to the AAA ATPase family. (438 aa)
	rpt-6	Protein CBR-RPT-6; Belongs to the AAA ATPase family. (417 aa)
	rpn-10	Protein CBR-RPN-10. (347 aa)
	rpt-5	Protein CBR-RPT-5; Belongs to the AAA ATPase family. (430 aa)
	CBG13260	Protein CBG13260. (251 aa)
	dss-1	Probable 26S proteasome complex subunit dss-1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Has an essential role in oogenesis and larval growth. Required for intestinal function and default lifespan (By similarity). (76 aa)
	CBG15320	Protein CBG15320. (429 aa)
	rpn-6.1	Protein CBR-RPN-6.1. (404 aa)
	CBG16572	Protein CBG16572. (324 aa)
	CBG16582	Protein CBG16582. (228 aa)
	CBG18037	Protein CBG18037. (490 aa)
	rpn-3	Protein CBR-RPN-3. (506 aa)
	rpn-13	Protein CBG19693. (375 aa)
	CBG19694	Protein CBG19694. (143 aa)
	rpn-7	Protein CBR-RPN-7. (409 aa)
	rpt-1	Protein CBR-RPT-1; Belongs to the AAA ATPase family. (435 aa)
	CBG20339	Protein CBG20339; Belongs to the AAA ATPase family. (415 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG04772	CBG06852	A8WYF6	A8X380	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG06852.	0.819
CBG04772	CBG09111	A8WYF6	A8X7S1	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG09111.	0.742
CBG04772	CBG11069	A8WYF6	A8XCC1	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG11069; Belongs to the AAA ATPase family.	0.975
CBG04772	CBG13260	A8WYF6	A8XHF2	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG13260.	0.725
CBG04772	CBG15320	A8WYF6	A8XLX6	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG15320.	0.952
CBG04772	CBG16572	A8WYF6	A8XPI1	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG16572.	0.957
CBG04772	CBG16582	A8WYF6	A8XPI7	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG16582.	0.957
CBG04772	CBG18037	A8WYF6	A8XSW1	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG18037.	0.914
CBG04772	CBG19694	A8WYF6	A8XW79	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG19694.	0.975
CBG04772	CBG20339	A8WYF6	G2J711	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG20339; Belongs to the AAA ATPase family.	0.959
CBG04772	CBG23920	A8WYF6	A8WJL1	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG23920; Belongs to the AAA ATPase family.	0.958
CBG04772	dss-1	A8WYF6	A8XLU5	Protein CBG04772; Belongs to the AAA ATPase family.	Probable 26S proteasome complex subunit dss-1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis. Has an essential role in oogenesis and larval growth. Required for intestinal function and default lifespan (By similarity).	0.931
CBG04772	rpn-1	A8WYF6	A8X1T6	Protein CBG04772; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.989
CBG04772	rpn-10	A8WYF6	A8XFP3	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBR-RPN-10.	0.996
CBG04772	rpn-11	A8WYF6	A8WJN2	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBR-RPN-11.	0.995
CBG04772	rpn-12	A8WYF6	A8WTE5	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBR-RPN-12.	0.995
CBG04772	rpn-13	A8WYF6	A8XW78	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBG19693.	0.975
CBG04772	rpn-2	A8WYF6	A8WKC2	Protein CBG04772; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.983
CBG04772	rpn-3	A8WYF6	A8XT32	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBR-RPN-3.	0.992
CBG04772	rpn-5	A8WYF6	A8WX64	Protein CBG04772; Belongs to the AAA ATPase family.	Protein CBR-RPN-5.	0.992