(33 nodes) Cortical cytoskeleton network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CBG00040	Protein CBG00040. (1622 aa)
	CBG01565	Protein CBG01565. (188 aa)
	wsp-1	Protein CBR-WSP-1. (785 aa)
	ani-2	Protein CBR-ANI-2. (1038 aa)
	pkc-3	Protein kinase C-like 3; Required for the normal progression of embryogenesis and viability of the organism. Plays an indispensable role in establishing embryonic polarity and in recruiting and maintaining par-6 to the periphery, through interaction with par-3. Required for epithelial cell polarity in the distal spermatheca. Phosphorylates serine residues of num-1. Required for the expression of antimicrobial peptide nlp-29 in response in response to fungal infection or physical injury. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
	unc-94	Protein CBR-UNC-94. (406 aa)
	CBG05921	Protein CBG05921. (299 aa)
	CBG06864	Protein CBG06864. (237 aa)
	lgl-1	Protein CBR-LGL-1. (969 aa)
	unc-10	Protein CBR-UNC-10. (1636 aa)
	ani-1	Protein CBR-ANI-1. (1199 aa)
	nab-1	Protein CBR-NAB-1. (742 aa)
	spd-5	Protein CBR-SPD-5. (1238 aa)
	spc-1	Protein CBR-SPC-1. (2467 aa)
	unc-78	Protein CBR-UNC-78. (611 aa)
	CBG16321	Protein CBG16321. (2870 aa)
	cyk-1	Protein CBR-CYK-1. (1477 aa)
	CBG16900	Protein CBG16900. (944 aa)
	CBG17418	Protein CBG17418. (2818 aa)
	act-5	Protein CBR-ACT-5. (375 aa)
	dbn-1	Protein CBG18266. (672 aa)
	unc-70	Spectrin beta chain; Belongs to the spectrin family. (2370 aa)
	CBG20816	Protein CBG20816. (169 aa)
	CBG20818	Protein CBG20818. (136 aa)
	CBG20825	Protein CBG20825. (561 aa)
	elks-1	Protein CBR-ELKS-1. (743 aa)
	CBG21068	Protein CBG21068. (462 aa)
	CBG21067	Protein CBG21067. (183 aa)
	aipl-1	Protein CBR-TAG-216. (599 aa)
	CBG22703	Protein CBG22703. (914 aa)
	atn-1	Protein CBR-ATN-1. (894 aa)
	CBG27262	Protein CBG27262. (332 aa)
	CBG16668	Protein CBG16668. (2334 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG00040	cyk-1	A8WM69	A8XPD1	Protein CBG00040.	Protein CBR-CYK-1.	0.665
CBG01565	act-5	A8WRD1	A8XS95	Protein CBG01565.	Protein CBR-ACT-5.	0.609
CBG01565	cyk-1	A8WRD1	A8XPD1	Protein CBG01565.	Protein CBR-CYK-1.	0.480
CBG01565	dbn-1	A8WRD1	A8XSA4	Protein CBG01565.	Protein CBG18266.	0.541
CBG01565	wsp-1	A8WRD1	A8WRD2	Protein CBG01565.	Protein CBR-WSP-1.	0.900
CBG05921	CBG21067	A8X1C0	A8XZ99	Protein CBG05921.	Protein CBG21067.	0.431
CBG05921	CBG21068	A8X1C0	A8XZ98	Protein CBG05921.	Protein CBG21068.	0.431
CBG05921	elks-1	A8X1C0	A8XZ97	Protein CBG05921.	Protein CBR-ELKS-1.	0.431
CBG16668	unc-70	E3CU57	A8XUM5	Protein CBG16668.	Spectrin beta chain; Belongs to the spectrin family.	0.898
CBG17418	CBG21067	A8XR05	A8XZ99	Protein CBG17418.	Protein CBG21067.	0.784
CBG17418	CBG21068	A8XR05	A8XZ98	Protein CBG17418.	Protein CBG21068.	0.784
CBG17418	elks-1	A8XR05	A8XZ97	Protein CBG17418.	Protein CBR-ELKS-1.	0.784
CBG17418	unc-10	A8XR05	A8XC13	Protein CBG17418.	Protein CBR-UNC-10.	0.452
CBG20816	CBG20825	A8XYP4	A8XYQ2	Protein CBG20816.	Protein CBG20825.	0.418
CBG20825	CBG20816	A8XYQ2	A8XYP4	Protein CBG20825.	Protein CBG20816.	0.418
CBG21067	CBG05921	A8XZ99	A8X1C0	Protein CBG21067.	Protein CBG05921.	0.431
CBG21067	CBG17418	A8XZ99	A8XR05	Protein CBG21067.	Protein CBG17418.	0.784
CBG21067	unc-10	A8XZ99	A8XC13	Protein CBG21067.	Protein CBR-UNC-10.	0.921
CBG21068	CBG05921	A8XZ98	A8X1C0	Protein CBG21068.	Protein CBG05921.	0.431
CBG21068	CBG17418	A8XZ98	A8XR05	Protein CBG21068.	Protein CBG17418.	0.784