STRINGSTRING
CBG14733 CBG14733 unc-40 unc-40 pgrn-1 pgrn-1 crn-7 crn-7 pxn-2 pxn-2 atf-7 atf-7 spe-49 spe-49 fsn-1 fsn-1 CBG19258 CBG19258 smp-1 smp-1 zip-3 zip-3 CBG22010 CBG22010 CBG23464 CBG23464 CBG13515 CBG13515 slt-1 slt-1 nol-6 nol-6 jnk-1 jnk-1 vhp-1 vhp-1 CBG02117 CBG02117 goa-1 goa-1 mab-20 mab-20 tsp-9 tsp-9 CBG08400 CBG08400 smp-2 smp-2 efa-6 efa-6 octr-1 octr-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBG14733Protein CBG14733. (509 aa)
unc-40Protein CBR-UNC-40. (1407 aa)
pgrn-1Protein CBR-PGRN-1. (291 aa)
crn-7Protein CBR-CRN-7. (367 aa)
pxn-2Protein CBR-PXN-2. (1366 aa)
atf-7Protein CBR-ATF-7. (519 aa)
spe-49Protein CBG18903. (783 aa)
fsn-1F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf-2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM and [...] (332 aa)
CBG19258Protein CBG19258. (513 aa)
smp-1Protein CBR-SMP-1; Belongs to the semaphorin family. (714 aa)
zip-3Protein CBR-ZIP-3. (286 aa)
CBG22010Sulfhydryl oxidase. (162 aa)
CBG23464Protein CBG23464. (800 aa)
CBG13515Protein CBG13515. (589 aa)
slt-1Protein CBR-SLT-1. (1376 aa)
nol-6Nucleolar protein 6. (1037 aa)
jnk-1Mitogen-activated protein kinase. (464 aa)
vhp-1Protein CBR-VHP-1. (672 aa)
CBG02117Protein CBG02117. (515 aa)
goa-1Protein CBR-GOA-1. (323 aa)
mab-20Semaphorin-2A; Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. Involved in axon guidance. Probably by binding receptor plx-2, regulates fln-1-mediated remodeling of the actin cytoskeleton and thus [...] (656 aa)
tsp-9Tetraspanin. (233 aa)
CBG08400Protein CBG08400. (668 aa)
smp-2Protein CBR-SMP-2; Belongs to the semaphorin family. (689 aa)
efa-6Protein CBR-EFA-6. (836 aa)
octr-1Protein CBR-OCTR-1; Belongs to the G-protein coupled receptor 1 family. (406 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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